Romanian Society of Pharmaceutical Sciences

Farmacia Journal 4/2022

Volume 70 | Number 4 | Year 2022

Download this issue’s covers, and announcements.

  1. MINI-REVIEW ON THE IMPLICATIONS OF GENE POLYMORPHISM IN THE METABOLISM OF XENOBIOTICS

    1“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, 700115, Iași, Romania
    2“Alexandru Ioan Cuza” University of Iasi, Department of Research, Faculty of Biology, 700505, Iași, Romania
    3“Alexandru Ioan Cuza” University of Iasi, Department of Biology, Faculty of Biology, 700505, Iași, Romania
    4“C.I. Parhon” National Institute of Endocrinology, 011863, Bucharest, Romania
    5Center of Biomedical Research of the Romanian Academy, 700481, Iași Romania

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  2. ANALGESIC ED50 DICLOFENAC-EUGENOL COMBINATION EFFECT ON PROINFLAMMATORY CYTOKINES – IL-1β, IL-6, TNFα AND MAPKs – IN RAT MUSCLE

    1Region Altiplano Academic Coordination (UASLP), Autonomous University of San Luis Potosí, 78700, San Luis Potosí, Mexico
    2Basic Science Laboratory, Faculty of Dentistry Autonomous University of San Luis Potosí, 78890, San Luis Potosí, Mexico
    3Faculty of Chemical Sciences, Juarez University of the State of Durango, 34120, Durango, Mexico
    4Interdisciplinary Research Centre for Integral Regional Development, Durango Unit - National Polytechnic Institute (CIIDIR-IPN), 34220, Durango, Mexico

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  3. RECENT ADVANCES IN THE STUDY OF DERIVATIVES OF (EZ)-N’- BENZYLIDENE-(2RS)-2-(6-CHLORO-9H-CARBAZOL-2-YL) PROPANOHYDRAZIDE

    1Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia, 020956, Bucharest, Romania 2Faculty of Chemistry, University of Bucharest, 4-12 Regina Elisabeta, 030018 Bucharest, Romania
    3Supramolecular Organic and Organometallic Chemistry Centre, Department of Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany János, 400028 Cluj-Napoca, Romania
    4Department of Microbiology and Immunology, Faculty of Biology, University of Bucharest, 91-96 Splaiul Independenței, Bucharest, Romania
    5Research Institute of the University of Bucharest, University of Bucharest, 90 Panduri Road, Bucharest, Romania
    6Academy of Romanian Scientist, 54 Splaiul Independetei, Bucharest, Romania

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  4. QUALITY BY DESIGN APPROACH FOR THE DEVELOPMENT OF SALINOMYCIN AND GEMCITABINE COMBINATION THERAPY LIPOSOMES FOR COLORECTAL CANCER

    Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 V. Babeș Street, 400012, Cluj-Napoca, Romania

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  5. TWO BIOACTIVE COMPOUNDS, ROSMARINIC ACID AND SINAPIC ACID, DO NOT AFFECT THE DEPLETED GLUTATHIONE LEVEL IN THE LENSES OF TYPE 2 DIABETIC FEMALE RATS

    1Department of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Jagiellońska 4, 41-200 Sosnowiec, Poland
    2Society of Silesian Veterinary Polyclinics, Katowice, Poland

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  6. HYDROPHOBICALLY MODIFIED DEXTRAN ESTERS AS POTENTIAL EXTERNAL BIOCIDES

    1“Grigore T. Popa” University of Medicine and Pharmacy, Department of Microbiology, Faculty of Medicine, 16 University Street, 700115, Iaşi, Romania
    2“Al. I. Cuza” University of Iaşi, Faculty of Chemistry, Department of Organic Chemistry, 11 Carol I Avenue, 700506, Iaşi,
    Romania
    3“Petru Poni” Institute of Macromolecular Chemistry, Centre of Advanced Research in Bionanoconjugates and
    Biopolymers, 41A Grigore Ghica Voda Alley, Iaşi, 700487, Romania
    4“Petru Poni” Institute of Macromolecular Chemistry, Department of Natural Polymers, Bioactive and Biocompatible Materials, 41 A Grigore Ghica Voda Alley, 700487, Iaşi, Romania

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  7. RISK FACTORS, ORAL ANTICOAGULANTS-BASED THERAPEUTICAL APPROACHES AND COMORBIDITIES IN ATRIAL FIBRILLATION: 4216 PATIENTS FROM A ROMANIAN HOSPITAL

    1Department of Biomedical Sciences, Doctoral School of the University of Oradea, University of Oradea, Oradea, 410087, Romania
    2Pharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, 410087, Romania
    3Mathematics Department, Faculty of Mathematics and Computer Science, West University Timișoara, Timișoara, 30022, Romania
    4Medicine Program of Study, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, 410087, Romania
    5Department of Internal Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, 050474, Romania 6Clinical Emergency Hospital of Bucharest, Bucharest, 105402, Romania

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  8. MECHANISM OF RITUXIMAB IN THE TREATMENT OF NEUROMYELITIS OPTICA

    1Department of Neurology, Second Affiliated Hospital of Mudanjiang Medical University, Mudanjiang city, 157000, China
    2Ophthalmic Function Room, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang city, 157000, China
    3Department of Medical Function, Mudanjiang Medical University, Mudanjiang city, 157000, China
    4Department of Histology and Embryology, Mudanjiang Medical University, Mudanjiang city, 157000, China
    5Stem Cell Institute, Mudanjiang Medical University, Mudanjiang city, 157000, China

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  9. CHANGES IN BIOCHEMICAL PARAMETERS IN DIABETES AFTER SUCCESSFUL DIRECT-ACTING ANTIVIRAL TREATMENT OF HEPATITIS C VIRUS

    1Department of Medical Semiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
    2Department of Anatomy and Embryology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania 3Department of Cardiology, University and Emergency Hospital, 050098 Bucharest, Romania
    4Department of Hygiene and Medical Ecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest,
    Romania
    5Department of Surgery, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
    6Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
    7Department of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
    8Department of Medical and Surgical Specialties, Faculty of Medicine, Transylvania University of Brașov, 500019 Brașov, Romania

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  10. COMPARATIVE RESEARCH BETWEEN SOLIFENACINTAMSULOSIN VERSUS TAMSULOSIN ALONE IN EXPULSION OF JUXTAVESICAL URETERAL STONES

    1“Grigore T Popa” University of Medicine and Pharmacy, Faculty of Medicine, 16 Universității Street, Iași, Romania
    2“CI Parhon” Hospital, Department of Urology, 50 Carol I Boulevard, Iași, Romania
    3“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, 37 Dionisie Lupu Street, Bucharest, Romania
    4“Prof Dr Th Burghele” Clinical Hospital, 20 Panduri Street, Bucharest, Romania

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  11. EFFICACY OF NATURAL POLYPHENOLIC COMPOUNDS FROM BILBERRY AND BLUEBERRY ON THE METABOLIC ALTERATIONS INDUCED BY STREPTOZOTOCIN IN RATS

    1Department of Pharmacognosy and Phytotherapy, Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu-Mureș, 38 Gh. Marinescu Street, 540139, Târgu-Mureș, Romania
    2Emergency County Hospital Târgu Mureș, Department of Pathology, 50 Gh. Marinescu Street, 540136, Târgu Mureș, Romania 3Immunology Laboratory, Center for Advanced Medical and Pharmaceutical Research, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu-Mureș, 38 Gh. Marinescu Street, 540139, Târgu-Mureș, Romania
    4Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, “George Emil Palade” University of Medicine,
    Pharmacy, Science and Technology of Târgu-Mureș, 38 Gh. Marinescu Street, 540139, Târgu-Mureș, Romania
    5Department of Urology, Mureș County Clinical Hospital, 1 Gh. Marinescu Street, 540103, Târgu-Mureș, Romania
    6Department of Urology, Faculty of Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu-Mureș, 38 Gh. Marinescu Street, 540139, Târgu-Mureș, Romania

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  12. INFLUENCE OF SOLVENT TYPE ON THE PHENOLIC CONTENT AND ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES OF ECHIUM VULGARE L. EXTRACTS

    1University of East Sarajevo, Faculty of Agriculture, 71 123 East Sarajevo, Bosnia and Herzegovina 2University of Kragujevac, Faculty of Agronomy, 32 000 Čačak, Serbia

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  13. INFLUENCE OF TYPE 2 DIABETES ON THE ANTHROPOMETRIC INDICES, BODY COMPOSITION AND MICRONUTRIENT STATUS OF PATIENTS SUBMITTED TO LAPAROSCOPIC SLEEVE GASTRECTOMY

    1Department of Bromatology, Hygiene, Nutrition, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania
    2Department of Physiopathology, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012
    Cluj-Napoca, Romania 3“G. T. Popa” University of Medicine and Pharmacy, Iași, Romania
    4Department of Exact Sciences, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, 400372 ClujNapoca, Romania
    5Department of Pharmaceutical Botany, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania

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  14. ANTIOXIDANT AND IN VITRO CYTOTOXIC ACTIVITY OF COMMERCIAL LEMONGRASS, SEA BUCKTHORN AND BASIL ESSENTIAL OILS, AGAINST COLORECTAL CANCER CELL LINE HCT 116

    ALINA ANTON 1,2#, ELENA ALINA MOACĂ 1,2#, CRISTIAN ANDREI SARAU 3*, ȘTEFANIA
    DINU 4, ALEXANDRA DENISA SEMENESCU 1,2, IOANA GABRIELA MACAȘOI 1,2, CRISTINA ADRIANA DEHELEAN 1,2

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  15. TESTICULAR INJURIES DUE TO SUBACUTE COMBINED EXPOSURE TO CADMIUM AND LEAD IN RATS

    1Department Preclinics, Faculty of Veterinary Medicine, “Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine of Iaşi, 8 M. Sadoveanu, 700489 Iaşi, Romania
    2Department of Pharmaceutical Sciences I, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy of Iaşi, 16 Universităţii, 700115, Romania
    3Department of Exact Sciences, Faculty of Horticulture, “Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine of Iaşi, 3 M. Sadoveanu, 700490 Iaşi, Romania
    4Research Institute for Agriculture and Environment (ICAM), 14 M. Sadoveanu, 700489 Iaşi, Romania
    5Department Clinics, Faculty of Veterinary Medicine, “Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine of Iaşi, 8 Aleea M. Sadoveanu, 700489 Iaşi, Romania

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  16. EVALUATION OF ANTIPYRETICS USE AND HEAT SENSITIVITY IN PATIENTS WITH MULTIPLE SCLEROSIS AND IT IS IMPACT ON QOL

    1Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
    2Corporate of Pharmacy Services, King Saud University Medical City, Riyadh, Saudi Arabia

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  17. BREAST CANCER RESPONSE TO NEOADJUVANT CHEMOTHERAPY QUANTIFIED BY RESIDUAL CANCER BURDEN (RCB) SCORE

    1Department of General Surgery I, “Sf. Maria” Clinical Hospital, Bucharest, Romania
    2“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    3Department of Pathology, “Sf. Maria” Clinical Hospital, Bucharest, Romania 4Department of Oncology, “Sf. Maria” Clinical Hospital, Bucharest, Romania

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  18. SYNERGISTIC INTERACTION BETWEEN LAMIACEAE ESSENTIAL OILS AND ANTIFUNGAL DRUGS AGAINST CANDIDA ALBICANS ATCC 10231

    1Department of Microbiology and Virusology, Medical University of Varna, Bulgaria
    2Training Sector “Medical Laboratory Assistant”, Medical College-Varna, Medical University of Varna, Bulgaria
    3Training Sector “Assistant Pharmacist”, Medical College-Varna, Medical University of Varna, Bulgaria
    4Department of Pharmaceutical Chemistry, Pharmacy Faculty, Medical University of Varna, Bulgaria
    5Department of Social Medicine and Health Care Organization, Medical University of Varna, Bulgaria

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  19. EVALUATION OF TAPERING BIOLOGICAL THERAPY IN RHEUMATOID ARTHRITIS

    1Clinical County Emergency Hospital Oradea, 2 Corneliu Coposu Street, Oradea, Romania
    2University of Oradea, Doctoral School of Biomedical Sciences, Medicine Field, 1 Universității Street, Oradea, Romania 3Department of Drug Control, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy Bucharest, 6
    Traian Vuia Street, Bucharest, Romania
    4University of Oradea, Faculty of Medicine and Pharmacy, 29 Nicolae Jiga Street Oradea, Romania

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  20. SYSTEMIC AMPICILLIN DIMINISHES FORMALIN-INDUCED NOCICEPTION IN RATS

    1Pain Mechanisms Laboratory, Academic Division of Health Sciences, Autonomous Juarez University of Tabasco, Villahermosa, Tabasco, México
    2Cardiometabolism Laboratory, Academic Division of Health Sciences, Autonomous Juarez University of Tabasco,
    Villahermosa, Tabasco, México

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  21. ASCORBATE INHIBITS THE ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION MEDIATED RELAXATION IN RESISTANCE ARTERIES

    “Grigore T. Popa University” of Medicine and Pharmacy Iaşi, 16 Universităţii Street, 700115 Iași, România

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  22. ANTITUMOR EFFECTS OF ANLOTINIB HYDROCHLORIDE ON HUMAN PANCREATIC CANCER CELLS

    1Department of Oncology, Daqing Oilfield General Hospital, Daqing City, 163000, China
    2Department of Pharmacy, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang City, 157011, China

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  23. A NOVEL LC-MS/MS ANALYTICAL METHOD FOR SIMULTANEOUS DETECTION OF ARTICAINE, ARTICAINE ACID, LIDOCAINE AND MONOETHYLGLYCINEXYLIDIDE (MEGX) IN HUMAN PLASMA

    1Department of Oral surgery, Dental Faculty, Medical University of Plovdiv, Bulgaria
    2Department of Bioorganic chemistry, Faculty of Pharmacy Medical University of Plovdiv, Bulgaria

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  24. THE COVID-19 PANDEMIC′S IMPACT ON HEALTHCARE PROFESSIONALS′ MENTAL HEALTH

    1“Grigore T. Popa” University of Medicine and Pharmacy from Iaşi, Faculty of Medicine, III Medical Department, 16
    Universităţii Street, 700115, Iaşi, România
    2Socola Institute of Psychiatry, 36 Bucium Street,700282, Iași, Romania
    3“Grigore T. Popa” University of Medicine and Pharmacy from Iaşi, Faculty of Pharmacy, Department of Pharmaceutical
    Management and Marketing, 16 Universităţii Street, 700115, Iaşi, România
    4“Grigore T. Popa” University of Medicine and Pharmacy from Iaşi, Faculty of Medicine, Mother and Child Health Department, 16 Universităţii Street, 700115, Iaşi, Romania

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  25. THE ANALYSIS OF PRESCRIPTIONS AND DISTRIBUTION OF MEDICINES IN THE PREVENTION OF MEDICATION ERRORS IN COMMUNITY PHARMACIES

    1Vasile Procopisin Department of Social Pharmacy, “Nicolae Testemițanu” State University of Medicine and Pharmacy, Chișinău, Republic of Moldova
    2Nicolae Testemițanu Department of Social Medicine and Management, “Nicolae Testemițanu” State University of Medicine and Pharmacy, Chisinau, Republic of Moldova

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