Romanian Society of Pharmaceutical Sciences

Current Issue

Volume 70 | Number 2 Year 2022

Download this issue’s covers, and announcements.

  1. REVIEW DIETARY AND PHARMACO-THERAPY IN SKIN DISEASES

    1Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș,
    Romania
    2Department of Community Nutrition and Food Hygiene, Faculty of Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Romania
    3Richter Pharmacy no 7, Cluj-Napoca, Romania
    4Department of Analytical Chemistry and Drug Analysis, Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Romania

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  2. LATE-ONSET EPILEPSY IN THE ELDERLY: DIFFICULTIES OF DIAGNOSIS AND PERSONALIZED PHARMACOLOGICAL MANAGEMENT, WITH PARTICULARITIES TO COVID-19 PANDEMIC – SYSTEMATIC REVIEW OF LITERATURE

    1Neurorehabilitation Department, Teaching Emergency Hospital “Bagdasar-Arseni”, Bucharest, Romania
    2“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    3Computer Science Department, Polytechnic University of Bucharest, Bucharest, Romania
    4Geriatrics Department, “Sf. Luca” Hospital, Bucharest, Romania 5Ilfov County Emergency Clinical Hospital, Bucharest, Romania
    6Psychiatric Hospital “Dr. C. Gorgos” Bucharest, Romania

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  3. BOTULINUM TOXIN, TREATMENT OPTION FOR NEUROGENIC DETRUSOR OVERACTIVITY

    1“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    2University Hospital of the Canary Islands, Santa Cruz de Tenerife, Spain

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  4. DEVELOPMENT AND CHARACTERIZATION OF LORATADINE LIPOSOMAL GEL USING QbD APPROACH

    1Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy
    “Iuliu Hațieganu”, 41 Victor Babeș Street, 400012, Cluj-Napoca, Romania
    2Department of Dermopharmacy and Cosmetics, Faculty of Pharmacy, University of Medicine and Pharmacy “Iuliu Hațieganu”, 12 Ion Creangă Street, 400010, Cluj-Napoca, Romania

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  5. PHENOLICS CONTENT, ANTIOXIDANT POTENTIAL, α-GLUCOSIDASE AND α-AMYLASE INHIBITORY ACTIVITIES OF FOUR FOLIAR EXTRACTS FROM PINUS SPECIES

    The current study focused on determining the contents of total phenolics (TP), flavonoids (FC), condensed tannins (CT), the flavonoid profiles, antioxidant potentials and α-glucosidase and α-amylase inhibitory capacities of the foliar extracts of Pinus engelmannii Carr., Pinus arizonica Engelm., Pinus durangensis Martínez and Pinus cembroides Zucc. Specific variations were found in TP, FC, CT, antioxidant potentials and α-glucosidase and α-amylase inhibitory activities. Pinus durangensis highlighted for its high level of FC (3.70 mg/g dry extract), high DPPH● scavenging activity, high ABTS●+ reducing potential, as well as its high inhibitory activity of α-glucosidase and α-amylase, whereas Pinus engelmannii for its high values of TP (340.15 mg/g dry extract) and CT (72.49 mg/g dry extract). Particularly, Pinus durangensis could support the development of hypoglycaemic treatments. The flavonoid profiles obtained by HPLC were species-specific, thus may be used for the development of chemical fingerprinting and quality control tools for the botanical authenticity of the bioactive extracts of these species of Pinus.

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  6. DENATONIUM BENZOATE ATTENUATES INFLAMMATION AND PAIN AND DECREASES PGE2 LEVELS IN RATS

    1Department of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University-Plovdiv, 15A Vassil Aprilov Boulevard, 4002 Plovdiv, Bulgaria
    2Department of Medical Biology, Medical Faculty, Medical University-Plovdiv, 15A Vassil Aprilov Boulevard, 4002 Plovdiv, Bulgaria
    3Research Institute at Medical University-Plovdiv, 15A Vassil Aprilov Boulevard, 4002 Plovdiv, Bulgaria
    4Department of Medical Physics and Biophysics, Faculty of Pharmacy, Medical University-Plovdiv, 15A Vassil Aprilov Boulevard, 4002 Plovdiv, Bulgaria

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  7. A QSAR STUDY ON THIOUREA DERIVATIVES – NEW APPROACHES IN DRUG DEVELOPMENT

    1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6
    Traian Vuia Street, 020956 Bucharest, Romania
    2National Institute of Chemical-Pharmaceutical Research & Development, 112 Vitan Avenue, 031299 Bucharest, Romania

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  8. PHYTOCHEMICAL COMPOSITION AND IN VITRO BIOLOGICAL PROPERTIES OF SEVERAL RUDBECKIA HIRTA AND TAGETES ERECTA FLOWER EXTRACTS

    1Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 16 University Street, 700115, Iași, Romania 2Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012, Cluj-Napoca,
    Romania 3Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 University Street, 700115, Iași, Romania 4National Institute of Chemical Pharmaceutical R&D (INCDCF), 112 Vitan Road, 031299, Bucharest, Romania 5Department of Pharmaceutical Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, 800010 Galați, Romania

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  9. PHYTOCHEMICAL SCREENING AND BIOLOGICAL ACTIVITY OF ETHANOLIC EXTRACT OF ROSA X DAMASCENA MILL. CULTIVATED IN THE WESTERN REGION OF ROMANIA

    1Doctoral School of Biomedical Science, University of Oradea, 1 University Street, 410087, Oradea, Romania
    2Faculty of Medicine and Pharmacy, University of Oradea, 10 Piața 1 Decembrie Street, 410073, Oradea, Romania
    3Department of Pharmaceutical Biochemistry and Clinical Laboratory, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012, Cluj-Napoca, Romania
    4Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, 98 Nagyerdei körút Street, 4032, Debrecen, Hungary
    5Department of Inorganic Chemistry, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012, Cluj-Napoca, Romania
    6Paraclinic/Clinic Department, Faculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 3-5 Mănăștur Road, 400372, Cluj-Napoca, Romania 7Department of Pharmaceutical Botany, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012, Cluj-Napoca, Romania
    8Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, “Iuliu Hațieganu” University of
    Medicine and Pharmacy, 8 Victor Babeș Street, 400012, Cluj-Napoca, Romania

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  10. CYTOTOXIC EVALUATION OF ORIGINAL PYRAZOLO[3,4d]THIAZOLES AND PYRAZOLO[3,4-c]PYRAZOLES

    1Institut de Chimie Organique et Analytique (ICOA), Université d’Orleans UMR CNRS 7311, BP 6759, 45067 Orléans
    Cedex 2, France
    2Center of Applied Chemistry and Process Engineering (CAIP), University Vasile Alecsandri of Bacău, 157 Calea Mărăşeşti Street, Bacău, 600115, Romania

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  11. CLASS II PHOSPHATIDYLINOSITOL 3-KINASE 2ß IS A NOVEL TARGET FOR THE POTENTIAL DEVELOPMENT OF ANTIVIRAL DRUGS AGAINST THE HEPATITIS B VIRUS

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  12. POLYPHENOLIC PROFILE AND ANTI-INFLAMMATORY, ANALGESIC AND ANTIOXIDANT EFFECTS OF ETHANOLIC AND HYDRO-ETHANOLIC EXTRACTS OF HEINSIA CRINITA AFZ.G. TAYLOR AND TETRACERA ALNIFOLIA WILLD

    1Laboratory of Chemistry of Organic Biomolecules and Pharmacodynamics, Department of Pharmacopoeia and Traditional
    Medicine, National Institute for Research in Health Sciences (IRSSA), Cité Scientifique, Brazzaville, Congo
    2Department of Pharmacology, Physiology and Physiopathology, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012, Cluj-Napoca, Romania
    3Animal Physiology and Physiopathology Laboratory, Faculty of Science and Technology, Marien Ngouabi University, Brazzaville, BP 69, Congo
    4Department of Pharmacognosy, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012, Cluj-Napoca, Romania
    5Department of Pharmaceutical Botany, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, 8 Victor Babeș Street, 400012, Cluj-Napoca, Romania
    6Laboratory of Biochemistry and Pharmacology, Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, B.P. 69, Congo

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  13. REDUCED BONE MINERAL DENSITY IN YOUNG, NON-CIRRHOTIC PATIENTS WITH CHRONIC VIRAL HEPATITIS

    1“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    2“Prof. Dr. Matei Balș” National Institute for Infectious Diseases, Bucharest, Romania 3“Dr. I. Cantacuzino” Clinical Hospital, Bucharest, Romania

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  14. LC–ESI-MS/MS-BASED PHYTOCHEMICAL PROFILE, ANTIOXIDANT AND ENZYME INHIBITION ACTIVITIES OF EXTRACTS FROM COUSINIA AINTABESIS BOISS. & HAUSSKN

    1Department of Pharmacognosy, Faculty of Pharmacy, Erciyes University, Kayseri 38030, Turkey
    2Department of Pharmaceutical Botany, Faculty of Pharmacy, Selçuk University, Konya 42250, Turkey

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  15. DETECTION OF ESCHERICHIA COLI FROM NON-STERILE HERBAL PHARMACEUTICAL PRODUCTS FROM THE ROMANIAN MARKET

    “George Emil Palade” University of Medicine, Pharmacy, Sciences, and Technology of Târgu Mureș, Faculty of Pharmacy,
    Cell Biology and Microbiology Department, 38 Gh. Marinescu Street, 540139, Târgu Mureș, Romania

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  16. CYTOMEGALOVIRUS INFECTION AND CARDIOVASCULAR RISK IN A MONOCENTRIC ROMANIAN ADULT PATIENT GROUP

    1Romanian Academy, 125 Calea Victoriei, 010071, Bucharest, Romania
    2“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, 020956, Bucharest,
    Romania
    3“Ștefan S. Nicolau” Institute of Virology, 285 Mihai Bravu Road, 030304, Bucharest, Romania
    4Colțea Clinical Hospital, 1 Ion C. Brătianu Boulevard, 030171, Bucharest, Romania
    5National Reference Centre for Herpesviruses, University of Limoges, INSERM Laboratory, UMR 1092, 2 Rue du Pr Descottes, 87000 Limoges, France
    6“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, 8 Eroii Sanitari Street, 050474, Bucharest, Romania

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  17. IMPROVING STRUCTURE BASED MODELS FOR PREDICTING CHEMICAL FUNCTIONS AND WEIGHT FRACTIONS IN COSMETIC PRODUCTS USING ENSEMBLE SUPPORT VECTOR MACHINE

    1University of Montenegro, Faculty of Medicine, Pharmacy study program, Krusevac bb, 81 000 Podgorica, Montenegro 2University of Montenegro, Faculty of Economics, 37 Bulevar Jovana Tomasevica, 81000 Podgorica, Montenegro

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  18. 5-HYDROXITRYPTOPHAN DIETARY SUPPLEMENTATION IN POST-TRAUMATIC STRESS SYNDROME

    1“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania 2Clinical Emergency Hospital, Bucharest, Romania
    3“Dr. Victor Gomoiu” Clinical Children Hospital, Bucharest, Romania

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  19. THE EFFECT OF PROPOFOL ON THE PROLIFERATION OF NEPHROBLASTOMA CELLS AND THE UNDERLYING MECHANISM

    1First Clinical Medical College, Mudanjiang Medical University, Mudanjiang, 157011, China
    2Department of Anesthesiology, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang, 157011, China
    3Department of Anesthesiology, Hengqin Branch of Zhuhai People's Hospital, Zhuhai, 519000, China

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  20. INFLUENCE OF DISSOLUTION CONDITIONS ON THE DISSOLUTION RATE AND RELEASE MECHANISM OF KETOPROFEN FROM EXTENDED RELEASE HYDROPHILIC MATRIX SYSTEMS

    1Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012, Cluj-Napoca, Romania
    2Department of Medical Devices, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400349, Cluj-Napoca, Romania

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  21. DESIGN, SYNTHESIS, BIOLOGICAL EVALUATION AND MOLECULAR DOCKING OF PYRROLE-BASED COMPOUNDS AS ANTIOXIDANT AND MAO-B INHIBITORY AGENTS

    1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University – Sofia, Bulgaria
    2Department of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University – Sofia, Bulgaria 3Department of Chemistry, Faculty of Pharmacy, Medical University – Sofia, Bulgaria

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  22. THERAPIES AND BONE IMPAIRMENT IN INFLAMMATORY BOWEL DISEASE YOUNG ADULTS

    1“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    2Department of Endocrinology, Diabetes and Metabolic Diseases, Elias University and Emergency Hospital, Bucharest, Romania
    3Department of Gastroenterology, Fundeni Clinical Institute, Bucharest, Romania
    4Department of Gastroenterology, Colentina Hospital, Bucharest, Romania
    5Department of Gastroenterology, Elias University and Emergency Hospital, Bucharest, Romania

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  23. ANTINOCICEPTIVE EFFECT OF 4-ALLYL-2-METHOXYPHENOL AND DICLOFENAC CO-ADMINISTRATION IN THE FORMALIN TEST IN RATS

    1Region Altiplano Academic Coordination, Autonomous University of San Luis Potosí. San Luis Potosí, México
    2Pharmacy Department, Division of Natural and Exact Sciences, University of Guanajuato, México
    3Faculty of Dentistry Autonomous University of San Luis Potosí. San Luis Potosí, México
    4Food and Nutrition Center, Faculty of Medicine and Nutrition, Juarez University of the State of Durango, México
    5Faculty of Chemical Sciences, Juarez University of the State of Durango, México

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  24. ROLE OF THE PHARMACIST IN IMPROVING INHALER TECHNIQUE IN PATIENTS’ OPINION IN POZNAN (POLAND)

    1Pharmacy Practice Division, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznan, Poland
    2Student’s Pharmaceutical Care Group, Department of Pharmaceutical Technology, Pharmacy Practice Division, Poznan
    University of Medical Sciences, 6 Grunwaldzka Street, 60-780 Poznan, Poland
    3Polish Pharmaceutical Chamber, 77 lok. 6 Żeromskiego Street, 01-882 Warsaw, Poland
    4Department of Infectious Diseases and Allergology, Military Institute of Medicine, Szaserów Street 128, 04-141 Warsaw, Poland 5Chair and Department of Computer Science and Statistics, Poznan University of Medical Sciences, 7 Rokietnicka Street, 60806 Poznan, Poland
    6Department of Organic Chemistry, Medical University of Warsaw, 1 Banacha Street, 02-097 Warsaw, Poland

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  25. KNOWLEDGE AND ATTITUDE OF PHARMACY STUDENTS TOWARDS COVID-19 PANDEMIC AND ITS IMPACT ON THEIR EDUCATION AND LEARNING

    1Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
    2College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia

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