Current Issue
Volume 69 | Number 1 Year 2021
Download this issue’s covers and announcements.
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THE IMPACT OF COVID-19 LOCKDOWN ON THE LIFESTYLE AND DIETARY PATTERNS AMONG ROMANIAN POPULATION
MAGDALENA MITITELU 1#, TIBERIUS IUSTINIAN STANCIU 2#, DENISA IOANA UDEANU 1*, DANIELA ELENA POPA 1, DOINA DRĂGĂNESCU 1, CĂLIN COBELSCHI 3, NICOLETA DIANA GRIGORE 1, ANCA LUCIA POP 1#, MANUELA GHICA 1
1.“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2.“Ovidius” University of Constanța, Constanța, Romania
3.Faculty of Medicine, Transilvania University, Brașov, Romania -
CYTOTOXIC EFFECT OF CHLOROFORM EXTRACTS FROM TANACETUM VULGARE, T. MACROPHYLLUM AND T. CORYMBOSUM ON HELA, A375 AND V79 CELL LINES
BIANCA IVĂNESCU 1#, CARMEN ELENA POP 2*, LAURIAN VLASE 3#, ANDREIA CORCIOVĂ 4, DANIELA GHERGHEL 5, GABRIELA VOCHITA 5, CRISTINA TUCHILUȘ 6, CONSTANTIN MARDARI 7, COSMIN MIHAI TEODOR 8
1.Department of Pharmaceutical Botany, “Gr. T. Popa” University of Medicine and Pharmacy, 16 Universității Street, Iași, Romania
2.Department of Drug Industry and Pharmaceutical Biotechnologies, “Iuliu Hațieganu” University of Medicine and Pharmacy, 12 Ion Creangă Street, Cluj-Napoca, Romania
3.Department of Pharmaceutical Technology and Biopharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 12 Ion Creangă Street, Cluj-Napoca, Romania
4.Department of Drugs Analysis, “Gr. T. Popa” University of Medicine and Pharmacy, 16 Universității Street, Iași, Romania
5.Institute of Biological Research, 47 Lascăr Catargi Street, 700107, Iași, Romania
6.Department of Microbiology, “Gr. T. Popa” University of Medicine and Pharmacy, 16 Universității Street, Iași, Romania
7.“Anastasie Fătu” Botanical Garden, “Alexandru Ioan Cuza” University of Iași, 7-9 Dumbrava Roșie Street, Iași, Romania
8.Advanced Centre for Research and Development in Experimental Medicine, “Gr. T. Popa” University of Medicine and Pharmacy, 9 Kogălniceanu Street, Iași, Romania -
A PROCESS ANALYTICAL TECHNOLOGY (PAT) APPROACH TO EVALUATE GABAPENTIN DISTRIBUTION IN LAMINAR EXTRUDATES
JOANNA RONOWICZ 1*, JOÃO F. PINTO 2
1.Department of Inorganic and Analytical Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, ul. Jurasza 2, 85-089 Bydgoszcz, Poland
2.Department of Galenic Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Lisbon, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal -
THE EFFECTS OF HISTAMINE ON THE CONTROL OF CORNEAL NEOVASCULAR MOTILITY IN RATS
DANIELA BIANCA DAMIAN 1, ISABEL GHIȚĂ 1*, RAZVAN DANIEL IONESCU 2, ION FULGA 1
1.Departament of Pharmacology and Pharmacotherapy, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2.Ophtalmic Emergency Clinical Hospital, Bucharest, Romania -
ASSESSMENT OF OLIVE LEAVES EXTRACT – CYTOTOXICITY IN VITRO AND ANGIOGENESIS IN OVO
MĂDĂLINA BORUGĂ 1#, VIRGIL ENĂTESCU 1#, IULIA PÎNZARU 2*, CAMELIA SZUHANEK 3, DALIANA MINDA 2, IASMINA MARCOVICI 2, DANIELA RADU 1, DANIELA MARȚI 4, BRIGITHA VLAICU 1, OANA SUCIU 1
1.“Victor Babeş” University of Medicine and Pharmacy Timișoara, Faculty of Medcine, 2 Eftimie Murgu Square, 300041, Timişoara, Romania
2.“Victor Babeş” University of Medicine and Pharmacy Timișoara, Faculty of Phamacy, 2 Eftimie Murgu Square, 300041, Timişoara, Romania
3.“Victor Babeş” University of Medicine and Pharmacy Timișoara, Faculty of Dental Medicine, 2 Eftimie Murgu Square, 300041, Timişoara, Romania
4.Western University Vasile Goldiș, Faculty of Medicine, 94 Revoluției Boulevard, 310025, Arad, Romania -
ASSESSMENT OF THE GRANULATION PROCESS EFFECT ON MORPHO-ANATOMICAL FEATURES AND BIOLOGICALLY ACTIVE SUBSTANCES COMPOSITION OF SENNA LEAVES
OLGA TRIFONOVA 1,2, OLGA EVDOKIMOVA 3, VERA PROKOFIEVA 4, HELGI SCHIÖTH 5,6, ALEXEY MATYUSHIN 7,8*
1.Department of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russian Federation
2.JSC “Krasnogorsklersredstva”, Krasnogorsk, Russian Federation
3.Federal State Budgetary Institution Scientific Centre for Expert Evaluation of Medicinal Products of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
4.A.P. Arzamastsev Department of Pharmaceutical and Toxicological Chemistry, Sechenov First Moscow State Medical University, Moscow, Russian Federation
5.Department of Neuroscience, Uppsala University, Uppsala, Sweden
6.Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, Moscow, Russian Federation
7.Department of Analytical and Forensic Toxicology, Sechenov First Moscow State Medical University, Moscow, Russian Federation
8.Institute of Linguistics and Intercultural Communication, Sechenov First Moscow State Medical University, Moscow, Russian Federation -
PHYTOCHEMICAL EVALUATION AND CYTOTOXICITY ASSAY OF LYTHRI HERBA EXTRACTS
IRINA MIHAELA IANCU 1, LAURA ADRIANA BUCUR 2*, VERGINICA SCHRODER 2, HORAȚIU MIREȘAN 2, MIHAI SEBASTIAN 2, VALERIU IANCU 2, VICTORIA BADEA 1
1.“Ovidius” University of Constanța, Faculty of Dental Medicine, Department of Microbiology, 7 Ilarie Voronca Street, Constanța, Romania
2.“Ovidius” University of Constanța, Faculty of Pharmacy, 6 Căpitan Al. Șerbănescu Street, Constanța, Romania -
VITIS VINIFERA L. AND SAMBUCUS NIGRA L. EXTRACTS ATTENUATE OXIDATIVE STRESS AND INFLAMMATION IN FEMORAL ISCHEMIA
CRISTINA BIDIAN 1, DANIELA-RODICA MITREA 1*, CORINA TATOMIR 2, MARIA PERDE-SCHREPLER 2, CAMELIA LAZĂR 3, IOANA CHEȚAN 1, POMPEI BOLFA 4,5, LUMINIȚA DAVID 6, SIMONA CLICHICI 1, GABRIELA ADRIANA FILIP 1, MARIANA MUREȘAN 7, OTILIA MICLE 7
1.Department of Physiology, “Iuliu Haţieganu” University of Medicine and Pharmacy, 1-3 Clinicilor Street, 400006, Cluj-Napoca, Romania
2.Department of Radiobiology and Tumour Biology, “Ion Chiricuță” Oncology Institute, 34-36 Republicii Street, 400015, Cluj-Napoca, Romania
3.Department of Morphopathology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400006 Cluj-Napoca, Romania
4.University of Agricultural Sciences and Veterinary Medicine, Department of Pathology, Cluj-Napoca, Romania
5.Ross University School of Veterinary Medicine, Department of Biomedical Sciences, Basseterre, St. Kitts, West Indies
6.Faculty of Chemistry and Chemical Engineering “Babeş-Bolyai” University, 11 Arany Janos Street, 400028, Cluj-Napoca, Romania
7.Department of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 10 Piața 1 Decembrie Street, 410073 Oradea, Romania -
PHENOLIC CONTENT, ANTIOXIDANT AND IN VITRO ANTIDIABETIC EFFECTS OF THIRTEEN MARINE ORGANISMS FROM MEDITERRANEAN SEA
DIDEM DELIORMAN ORHAN 1*, NILUFER ORHAN 1, OZGE DEMIR 2, BELMA KONUKLUGIL 2
1.Gazi University, Faculty of Pharmacy, Department of Pharmacognosy, 06330, Etiler Ankara, Turkey
2.Ankara University, Faculty of Pharmacy, Department of Pharmacognosy, 06100, Tandoğan Ankara, Turkey -
HEPARIN PROVIDES LONG TIME SURVIVAL FOR CIRCUITS IN THE NEONATAL AND INFANT CONTINUOUS RENAL REPLACEMENT THERAPY
MIHAELA BIZUBAC 1, CĂTĂLIN CIRSTOVEANU 1,4*, DOINA-ANCA PLEȘCA 4,5, CRISTINA MUSTEA 1, ANA-MARIA DAVIȚOIU 4,5, CRISTINA FILIP 3, ALIN NICOLESCU 3, RADU SPĂTARU 2,4
1.“M. S. Curie” Children’s Hospital, Neonatal Intensive Care Unit, Bucharest, Romania
2.“M. S. Curie” Children’s Hospital, Paediatric Surgery, Bucharest, Romania
3.“M. S. Curie” Children’s Hospital, Paediatric Cardiology, Bucharest, Romania
4.“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
5.“Victor Gomoiu” Children’s Hospital, Paediatrics, Bucharest, Romania -
NEUROHORMONAL AND PHARMACOLOGICAL REGULATION OF OESTROGEN, PROGESTERONE, LUTEINIZING HORMONE AND FOLLICLE STIMULATING HORMONE OVER THE MENSTRUAL CYCLE – THE POSSIBLE RELEVANCE OF ANGIONTENSIN II
ROXANA MIHAELA BARBU 1, ALIN CIOBÎCĂ 2,3,4, BOGDAN AURELIAN STANA 1, IONUȚ RĂDUCU POPESCU 1*, WALTHER BILD 1,2
1.“Gr. T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, Physiology Department, Iași, Romania
2.Center of Biomedical Research of the Romanian Academy, Iași, Romania
3.Department of Research, Faculty of Biology, ”Alexandru Ioan Cuza” University of Iași, 20A Carol I Avenue, Iași, Romania
4.Academy of Romanian Scientists, 54 Splaiul Independenței, sector 5, 050094, București, România -
BIOGENIC SYNTHESIS OF NANOSILVER PARTICLES FROM ROOT EXTRACT OF MORUS ALBA L. AND THEIR BIOLOGICAL ACTIVITIES
GHAZALA FARID MINHAS 1, BUSHRA HAFEEZ KIANI 2*, UZMA GHANI 1, KHAWAJA SHAFIQUE AHMAD 3, AALIA SHAH 1
1.Department of Biotechnology, Women University of Azad Kashmir, Bagh, AJK, Pakistan
2.Department of Biological Sciences, International Islamic University, Islamabad (44000), Pakistan
3.Department of Botany, Department of Botany, University of Poonch Rawalakot (AJ&K), Pakistan -
DISSOLUTION KINETIC OF MELOXICAM FROM HYDROPHILIC MATRIX-TYPE FILMS FOR TRANSDERMAL THERAPY
PAULA ANTONOAEA 1, EMŐKE MARGIT RÉDAI 1*, MAGDALENA BÎRSAN 2, ANAMARIA TĂTARU 1, NICOLETA TODORAN 1, ROBERT ALEXANDRU VLAD 1, DANIELA-LUCIA MUNTEAN 3, ADRIANA CIURBA 1
1.“George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, 38 Gheorghe Marinescu Street, 540142, Târgu Mureș, Romania
2.“Grigore T. Popa” University of Medicine and Pharmacy of Iași, Faculty of Pharmacy, Department of Pharmaceutical Technology, 16 Universității Street, 700115, Iași, Romania
3.“George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Faculty of Pharmacy, Department of Analytical Chemistry and Drug Analysis, 38 Gheorghe Marinescu Street, 540142, Târgu Mureș, Romania -
PROTECTIVE EFFECT AND MECHANISM OF SCHISANDRA CHINENSIS EXTRACT ON RETINAL PHOTORECEPTOR CELL INJURY
CAIHAN YU 1#, XINGGUANG HE 1#, XUDONG LV 1, LANLAN GONG 1, XINCHAO CHENG 1, JIE YANG 1, MENGNAN ZHU 1, ZHINONG WU 2*
1.Department of Ophthalmology, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of science and technology, Xianning, 437100, Hubei, China
2.Department of Clinical Laboratory, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of science and technology, Xianning, 437100, Hubei, China -
SILK FIBROIN NANOPARTICLES REVEAL EFFICIENT DELIVERY OF 5-FU IN A HT-29 COLORECTAL ADENOCARCINOMA MODEL IN VITRO
IONUȚ CRISTIAN RADU 1, ARIANA HUDIȚĂ 2, CĂTĂLIN ZAHARIA 1, CAROLINA NEGREI 3, GEORGE TRAIAN ALEXANDRU BURCEA DRAGOMIROIU 4, DANIELA ELENA POPA 4, MARIETA COSTACHE 2, HORIA IOVU 1, MARA GEORGESCU 7*, OCTAV GINGHINĂ 5,6, BIANCA GĂLĂȚEANU 2
1.Advanced Polymer Materials Group, Politehnica University of Bucharest, Bucharest, Romania
2.Department of Biochemistry and Molecular Biology, University of Bucharest, Romania
3.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Toxicology, Bucharest, Romania
4.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Drug Control, Bucharest, Romania
5.Department of Surgery, “Sf. Ioan” Clinical Emergency Hospital, Bucharest, Romania
6.“Carol Davila” University of Medicine and Pharmacy, Faculty of Dental Medicine, Department II, Bucharest, Romania
7.University of Agronomic Sciences and Veterinary Medicine of Bucharest, Faculty of Veterinary Medicine, 59 Mărăşti Boulevard, Bucharest, 011464, Romania -
CLINICAL STUDY REGARDING THE REHABILITATION TREATMENT OF OSTEOPOROTIC PATIENTS
FLORIN-MIHAI MARCU 1, LIVIU LAZĂR 1, FELICIA CIOARĂ 1, SEBASTIAN NEMETH 2*, SIMONA BUNGĂU 2, FLORIN BĂNICĂ 2
1.Department of Psycho-neurosciences and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410087, Oradea, Romania
2.Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028, Oradea, Romania -
COSMETIC PRODUCTS CONTAINING NATURAL BASED EMOLLIENTS FOR RESTORING IMPAIRED SKIN BARRIER: FORMULATION AND IN VIVO EVALUATION
MIRELA LILIANA MOLDOVAN *, IULIA IONUȚ, CĂTĂLINA BOGDAN
Department of Dermopharmacy and Cosmetics, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 12 I. Creangă Street, 400010, Cluj-Napoca, Romania
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PRETREATMENT WITH GLABRIDIN PREVENTS CARRAGEENAN-INDUCED INFLAMMATION: THE ROLES FOR CYTOKINES AND OXIDATIVE STRESS PRODUCTION
ALI PARLAR 1*, EBRU ANNAÇ 2, SEYFULLAH OKTAY ARSLAN 3, SALIHA AYŞENUR ÇAM 3
1.Department of Pharmacology, Faculty of Medicine, University of Adiyaman, Adiyaman, Turkey
2.Department of Histology and Embryology, Faculty of Medicine, University of Adiyaman, Adiyaman, Turkey
3.Department of Pharmacology, Faculty of Medicine, University of Ankara Yildirim Beyazit, Ankara, Turkey -
CYTO-HISTOPATHOLOGICAL AND PCR CORRELATION OF CATTLE PULMONARY HYDATID DISEASE
FLORICA BĂRBUCEANU 1,2*, GABRIEL PREDOI 2, CORINA-BEATRIS ANCUCEANU 1, STELIAN BĂRĂITĂREANU 2, ȘTEFANIA-FELICIA BĂRBUCEANU 3
1.Institute for Diagnosis and Animal Health, 63 Dr Staicovici D. Nicolae Street, 050557, Bucharest, Romania
2.University of Agricultural Science and Veterinary Medicine, Faculty of Veterinary Medicine, 105 Splaiul Independenței, 050097, Bucharest, Romania
3.Department of Organic Chemistry, “Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania -
INCREASING ENDURANCE IN PHYSICAL EFFORT BY ADMINISTRATION OF INOSINE
CĂTĂLIN PĂUNESCU 1#, GABRIEL PIŢIGOI 1#, GERMINA COSMA 2*, SILVIU MIREL PIȚURU 1, VASILICA GRIGORE 3, SILVIU PETRESCU 1#, MARIA LILIANA MIRCICĂ 1, MIHAELA RĂDULESCU 4, ALEXANDRU COSMA 2, RAMIN REZAEE 5, OANA CRISTINA PETRESCU 1
1.”Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, Bucharest, 020022, Romania
2.University of Craiova, Physical Education and Sport Faculty, 156 Brestei Street, Craiova, 200207, Romania
3.National University of Physical Education and Sport, 140 Constantin Noica Street, Bucharest, 060057, Romania
4.University of Economic Studies, 2-10 Căderea Bastiliei Street, Bucharest, 010615, Romania
5.Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran -
EFFECTS OF QUERCETIN ON CYTOKINES AND PULMONARY CAPILLARY CELLS IN PULMONARY ARTERIAL HYPERTENSION RATS
WEIQUN ZHANG 1, YAN LI 1, YONG LUO 1, DELI YE 2*
1.Department of Clinical Laboratory, The First People's Hospital of Lin'an District, Lin'an, Hangzhou 310000, Zhejiang, China
2.Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Hangzhou 310014, Zhejiang, China -
SYNTHESIS AND STRUCTURAL EXPLANATION OF MIXED LIGAND COMPLEXES OF SELENIUM(IV) WITH CAFFEINE AND SOME NITROGEN-BASED LIGANDS
FOZIAH A. AL-SAIF 1, JEHAN Y. AL-HUMAIDI 1, DALAL N. BINJAWHAR 1, SALHA E. ALOTAIBI 1, MOAMEN S. REFAT 2,3*
1.Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, KSA
2.Department of Chemistry, Faculty of Science, Taif University, Al-Haweiah, P.O. Box 888, Zip Code 21974, Taif, Saudi Arabia
3.Department of Chemistry, Faculty of Science, Port Said University, Port Said, Egypt -
DEVELOPMENT OF A DISSOLUTION TEST FOR MELATONIN SUBLINGUAL TABLETS USING A FACTORIAL EXPERIMENTAL DESIGN
LOURDES MAYET-CRUZ, JUAN MANUEL RODRÍGUEZ, HELGI JUNG-COOK *
Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México. C.P., 04510, Ciudad de México, México
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PREVALENCE OF TUBERCULOSIS IN SOUTH-WEST ROMANIA AND THE DIRECT COSTS BURDEN
ANDREEA-DANIELA MECA 1#, MIHAELA-SIMONA SUBȚIRELU 2#, ADINA TURCU-ȘTIOLICA 2*, FLOAREA MIMI NIȚU 3#, MARIA BOGDAN 1, MARIUS MATEI 4, RAMONA CIOBOATĂ 3, BOGDAN PETRE STĂNOIU 5, CĂTĂLINA-GABRIELA PISOSCHI 6
1.Department of Pharmacology, University of Medicine and Pharmacy, Craiova, Romania
2.Department of Pharmacoeconomics, University of Medicine and Pharmacy, Craiova, Romania
3.Department of Pneumology, University of Medicine and Pharmacy, Craiova, Romania
4.Department of Histology, University of Medicine and Pharmacy of Craiova, Romania
5.Department of Cell Biology, University of Medicine and Pharmacy, Craiova, Romania
6.Department of Biochemistry, University of Medicine and Pharmacy, Craiova, Romania -
REGULATIONS ON GREEN PHARMACY IN EUROPEAN COUNTRIES – A COMPARATIVE STUDY
ALEXANDRA TOMA *, OFELIA CRIŞAN
Department of Pharmaceutical Legislation and Management, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, 12 Ion Creangă Street, 400010, Cluj-Napoca, Romania