Current Issue
Volume 71 | Number 2 Year 2023
Download this issue’s covers, and announcements.
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CANDIDA AURIS: THE UNWELCOME SUPERFUNGUS
MARINA IONELA ILIE 1, BEATRICE MAHLER 1,2*, GINA CIOLAN 1,2, ALEXANDRU STOICHIȚĂ 1,2, OANA POPESCU 2, MĂDĂLINA PREDA 1,2, DENISA IOANA UDEANU 1,2, ANDREEA LETIȚIA ARSENE 1,2, ANCA FÂCĂ 2, DOINA DRĂGĂNESCU 1, VIOREL JINGA 1, BRUNO ȘTEFAN VELESCU 1
1“Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021, Bucharest, Romania
2“Marius Nasta” Pneumophthisiology Institute, 90 Viilor Road, 050159, Bucharest, Romania
*corresponding author: beatrice.mahler@umfcd.ro -
ADHERENCE TO TREATMENT – REVIEWING METHODS OF ASSESSMENT AND IMPROVEMENT
RĂZVAN-NICOLAE RUSU 1, DANIELA CARMEN ABABEI 1, GABRIELA DUMITRIȚA STANCIU 2, MONICA NEAMȚU 1, IOANA MACADAN 1*, CRISTINA IULIANA ANGHEL LAZĂR 3, VERONICA BILD 1
1Pharmacodynamics and Clinical Pharmacy Department, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania
2Center for Experimental Medicine “Prof. Ostin C. Mungiu”, Iași, Romania
3Physiology Department, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania -
THE ROLE OF TEMPERATURE AND pH IN THE SYNTHESIS OF SILVER NANOPARTICLES USING ARECA CATECHU L. SEED EXTRACT AS BIOREDUCTOR
MARDIYANTO MARDIYANTO, ELSA FITRIA APRIANI *, FITO PRATAMA HEYLKEN
Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Sriwijaya University, South Sumatra, Indonesia
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SYNTHESIS AND IN SILICO APPROACHES OF NEW SYMMETRIC BIS-THIAZOLIDINE-2,4-DIONES AS Ras AND Raf ONCOPROTEINS INHIBITORS
OVIDIU CRIȘAN 1, GABRIEL MARC 2*, CRISTINA NASTASĂ 2, SMARANDA ONIGA 3, LAURIAN VLASE 4, ADRIAN PÎRNĂU 5, OVIDIU ONIGA 2
1Department of Organic chemistry, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012, Cluj-Napoca, Romania
2Department of Pharmaceutical chemistry, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș Street, 4x00012, Cluj-Napoca, Romania
3Department of Therapeutical chemistry, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 12 Ion Creangă Street, 400010, Cluj-Napoca, Romania
4Department of Biopharmacy, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012, Cluj-Napoca, Romania
5National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, 400293 Cluj-Napoca, Romania -
FRUCTOSE INDUCED CHANGES IN RAT SERUM LIPIDS AND ADIPOSE TISSUE GENE EXPRESSION AND PREVENTIVE EFFECTS OF AGRIMONIA EUPATORIA AQUEOUS INFUSION INTAKE
Y. D. KISELOVA-KANEVA 1*, G. BEKYAROVA 2, N. F. NAZIFOVA 1, D. G. VANKOVA 1, D. G. IVANOVA 1, K. J. BRATOEVA 2
1Department of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University Varna, 84B Tzar Osvoboditel Street, Varna, 9000, Bulgaria
2Department of Physiology and Pathophysiology, Medical University Varna, 55 Marin Drinov Street, Varna, 9000, Bulgaria -
EXPLORING OF THE AMELIORATIVE EFFECTS OF ETHANOLIC EXTRACT OF THE WHEATGRASS (TRITICUM AESTIVUM L.) ON SURGICALLY INDUCED ENDOMETRIOSIS RAT MODEL
ABDULLAH ADIYAMAN 1, ABDULHAMİT BATTAL 2*, MERT İLHAN 3
1Department of Basic Pharmaceutical Sciences, Institute of Health Sciences, Van Yüzüncü Yıl University, 65080, Tusba, Van, Turkey
2Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Van Yüzüncü Yıl University, 65080, Tusba, Van, Turkey
3Department of Pharmacognosy, Faculty of Pharmacy, Düzce University, 81620, Düzce, Turkey -
SERUM ANTI – MULLERIAN HORMONE IN AZOOSPERMIA APPROACH
JIAO SHU 1, ZHIYONG LU 1, JIE XIA 1, MI XIANG 2*
1Department of Reproductive Medicine, Puren Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, 430081, Hubei, China
2Department of Obstetrics, Puren Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, 430081, Hubei, China -
EUGENOL: IN VITRO CHARACTERIZATION OF THE CYTOTOXIC PROFILE AT THE LEVEL OF COLORECTAL CARCINOMA CELLS
ROBERT COSMIN RACEA 1,2#, PETRU EUGEN MERGHES 3#, DANIELA GURGUS 4*, IOANA MACASOI 5,6, LAURA CRISTINA RUSU 1,2, DOINA CHIORAN 1, STEFANIA DINU 1,7, DANIEL BREBAN-SCHWARZKOPF 4, CAMELIA SZUHANEK 1, MIRCEA RIVIS 1
1Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 9 Revolutiei 1989 Avenue, 300070, Timișoara, Romania
2Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041 Timișoara, Romania
3Department of Physical Education and Sport, "King Mihai I" University of Life Sciences from Timișoara, 119 Aradului road, 300645 Timișoara, Romania
4Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
5Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
6Research Centre for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
7Paediatric Dentistry Research Centre, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 9 Eftimie Murgu Square, 300041, Timișoara, Romania -
BRAIN ANTIOXIDANT PROPERTIES OF PIPER CUBEBA L. EXTRACTS AND ESSENTIAL OIL
LUSI PUTRI DWITA 1,2, MARIA IMMACULATA IWO 1*, ELFAHMI 1, RACHMAT MAULUDIN 1
1School of Pharmacy, Institut Teknologi Bandung, Jl. Ganesha, 10, Bandung, 40132, Jawa Barat, Indonesia
2Faculty of Pharmacy and Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jakarta, Indonesia -
PROTECTIVE AND ANTIOXIDANT CAPACITY OF DATE PALM SEEDS (PHOENIX DACTYLIFERA L.) ON HEPATOTOXICITY IN RATS
AHMED GHANIA 1,2*, ALI BOUTLELIS DJAHRA 1,2
1El Oued University, Faculty of Life and Natural Sciences, Department of Molecular and Cellular Biology, Algeria
2Laboratory Biology, Environment, and Health (LBEH), Echahid Hamma Lakhdar University 39000, El-Oued, Algeria -
ANTIOXIDANT AND ANTICANCER EFFECT OF SOME PELARGONIUM SPECIES EXTRACTS
CRISTINA IANCU 1#, NINA FILIP 2, MĂDĂLINA MOCANU 2, CRISTINA ADRIANA DEHELEAN 3, CORINA DANCIU 3, OANA CIOANCĂ 1#, MONICA HĂNCIANU 1*, ANDREIA CORCIOVĂ 1, FLAVIA BURLEC 1, CORNELIA MIRCEA 1#, SILVIA ROBU 4
1Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115, Iași, Romania
2Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115, Iași, Romania
3Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041 Timișoara, Romania
4Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, 35 Al. I. Cuza Street, 800216, Galați, Romania -
SUBCHRONIC TOXICITY OF HOLOTHURIA ATRA ETHANOL EXTRACT FOR 90 DAYS IN HISTOPATHOLOGY OF THE LIVER AND KIDNEY OF RATS
MUHAMMAD NURSID 1*, ARIYANTI S. DEWI 1, GINTUNG PATANTIS 1, ENDAR MARRASKURANTO 1, USAMAH HABIBULLAH 2, MUHAMMAD R. SUBAGJA 2, SRI ESTUNINGSIH 2
1Research Center for Marine and Inland Water Bioindustry-National Research and Innovation Agency, Mataram, Indonesia
2Faculty of Veterinary Medicine, IPB University, Kampus IPB, Darmaga Bogor, Indonesia -
THE BENEFICIAL EFFECT OF DEXMEDETOMIDINE COMBINED WITH EPIDURAL-CONTROLLED ANALGESIA ON THE REDUCTION OF FEVER AND INFLAMMATION DURING LABOUR IN TERM-PREGNANT WOMEN
CAIFENG LI, LE YANG, JIANXIN GAO, LISHENG YI, DAN PENG, LAN DAI *
Department of Anaesthesiology, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, 410007, Hunan, China
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ROLE OF NITRIC OXIDE, IL-6, TNF-α AND PROSTAGLANDINS IN HEPATOPROTECTIVE EFFECT OF ILLICIUM VERUM ESSENTIAL OIL
MEHREEN NASIR 1, ALI SHARIF 1,2, IRFAN ANJUM 1*, ZAKA UR REHMAN 1
1Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan
2Institute of Pharmacy, Faculty of Pharmaceutical and Allied Health Sciences, Lahore College for Women University, Lahore, Pakistan -
DESIGN OF AZITHROMYCIN LOADED EUDRAGIT RL 100 NANOPARTICLES WITH EXTENDED ANTIBACTERIAL EFFECT
IRFAN AKARTAS 1*, AYSEGUL ATES 2
1Faculty of Pharmacy, European University of Lefke, Lefke, Turkish Republic of Northern Cyprus, (via Mersin 10, Turkey), Cyprus
2Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Ege University, Izmir, Turkey -
EXPERIMENTAL AND THEORETICAL INVESTIGATION OF ANTIOXIDANT ACTIVITY OF SOME DERIVATIVES WITH COUMARIN SCAFFOLD
GABRIELA TĂTĂRÎNGĂ 1*, BURAK TÜZÜN 2, ANA-MARIA ZBANCIOC 1
1“Grigore T. Popa” University of Medicine and Pharmacy Iași, Romania
2Technical Sciences Vocational School of Sivas, Sivas Cumhuriyet University, Sivas, Turkey -
OPTIMIZATION OF A FLOW CYTOMETRY PROTOCOL FOR PD-1/CTLA-4 IMMUNE CHECKPOINTS RECEPTORS DETECTION IN COLORECTAL CANCER TUMOUR MICROENVIRONMENT
MARIUS ZAMFIR 1,2, ARIANA HUDIȚĂ 3, MARA MARDARE 1,2, IRINA BONDOC 2, ANDREI VĂCĂRAȘU 2, BOGDAN COSMIN TĂNASE 2, GEORGE TRAIAN ALEXANDRU BURCEA-DRAGOMIROIU 4, MIRCEA LIȚESCU 5, THEODOR VOIOSU 6, BIANCA GĂLĂȚEANU 3*, CLAUDE LAMBERT 7, OCTAV GINGHINĂ 2,8
1Doctoral School of Medicine, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
2Department of Surgery 3, “Prof. Dr. Al. Trestioreanu” Institute of Oncology Bucharest, Romania
3Department of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, Romania
4Department of Drug Control, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
5Department of Surgery, “Sf. Ioan” Clinical Emergency Hospital, Bucharest, Romania
6Department of Gastroenterology, Colentina Clinical Hospital, Bucharest, Romania
7Immunology lab, Central University Hospital, Saint-Etienne, France
8Department II, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania -
C24H20N2O7, A NOVEL ISONICOTINAMIDE DERIVATIVE, REGULATES THE PROLIFERATION AND APOPTOSIS OF HepG2 CELLS THROUGH REGULATION OF AUTOPHAGY, ROS PRODUCTION AND THE ER
LING DUAN 1,2, ZHANGPING ZHOU 2, HONGDA LIU 3, ZHUOXUAN LIANG 2, SONG TENG 2, XIAOQIONG HE 2*, QIAN YAO 4
1Department of clinical Nutrition, The First People’s Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, Kunming, 650032, China
2School of Public Health, Kunming Medical University, Kunming, 650500, China
3School of Nursing, Kunming Medical University, Kunming, 650500, China
4Department of Yunnan Cancer Center, The Third Affiliated Hospital to Kunming Medical University, Kunming, 650100, China -
PENTOXIFYLLINE AND INFLAMMATION MARKERS IN PATIENTS WITH ACUTE CORONARY SYNDROME
DANIEL MIRON BRIE 1, CRISTIAN MORNOS 1,2, DIDUTA ALINA BRIE 3*, TUDOR LUCA CONSTANTIN 1,2, LUCIAN PETRESCU 1,2, MADALINA BORUGA 4
1Department of Interventional Cardiology, Cardiovascular Disease Institute Timișoara, 13A Gheorghe Adam Street, 300310, Timișoara, Romania
2Department of Cardiology, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
3Department of Cellular Biology, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
4Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania -
THE EFFECT OF EXTRACTION METHOD OF VERNONIA AMYGDALINA DELILE. LEAVES ON CARDIOTONIC EFFECT
DENNY SATRIA 1*, URIP HARAHAP 2, AMINAH DALIMUNTHE 2, TRIANA HERTIANI 3, RONY ABDI SYAHPUTRA 2, MAHATIR MUHAMMAD 1, NASRI NASRI 1,4
1Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Sumatera Utara, Jl. Tri Dharma No. 5 Kampus USU, Medan, Sumatera Utara, Indonesia
2Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Jl. Tri Dharma No. 5, Kampus USU, Medan, Sumatera Utara, Indonesia
3Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara, Yogyakarta,
4Department of Pharmacy, Sekolah Tinggi Ilmu Kesehatan (STIKes) Senior Medan, Jl. Jamin Ginting KM.8,5 No.13, Mangga, Medan Tuntungan, Sumatera Utara, Indonesia -
PHYSICO-CHEMICAL PARAMETERS USED FOR SOIL CHARACTERIZATION AND POLLUTION EVALUATION IN RACOS VOLCANO AREA, BRAȘOV, ROMANIA
LILIANA AVASILCAI 1#, OANA CIOANCA 1*, BRANCO-ADRIAN MORARIU 1, IONUT IULIAN LUNGU 1, MADALINA VIERIU 1#, CORNELIU TANASE 2, SILVIA ROBU 3#, MONICA HANCIANU 1, IONELA-DANIELA MORARIU 1
1Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy Iași, Romania
2Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Romania
3Faculty of Medicine and Pharmacy, “Dunărea de Jos” University of Galați, Romania -
INPATIENT PHARMACIST INTERVENTIONS IN REDUCING PRESCRIPTION-RELATED MEDICATION ERRORS IN INTENSIVE-CARE UNIT (ICU) IN RIYADH, SAUDI ARABIA
ABDULAZIZ ALHOSSAN 1, 2*, WAAD ALHUQBANI 1, AHMED ABOGOSH 1, OMER ALKHEZI 3, MOHAMMED ALESSA 1, AJAZ AHMAD 1
1Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
2Corporate of Pharmacy Services, King Saud University Medical City, Riyadh, Saudi Arabia
3Department of Pharmacy Practice, Unaizah College of Pharmacy, Qassim University, Qassim, Saudi Arabia -
BULGARIAN PHARMACISTS’ ATTITUDES AND BARRIERS TOWARDS PHARMACEUTICAL CARE PROVISION FOR INCREASING IMMUNITY IN CHILDREN
ANNA MIHAYLOVA ¹*, BOZHIDARKA HADZHIEVA ², DANIEL ARGILASHKI ², PETYA KASNAKOVA ¹, ELINA GUEORGUIEVA ³, STANISLAV GUEORGUIEV ⁴, MARIA SEMERDJIEVA ¹, DESISLAVA BAKOVA ¹
¹Department of Health Care Management, Faculty of Public Health, Medical University of Plovdiv, Plovdiv, Bulgaria, 15A Vasil Aprilov Street, 4002 Plovdiv, Bulgaria
²Medical College, Medical University of Plovdiv, Plovdiv, Bulgaria, 15A Vasil Aprilov Street, 4002 Plovdiv, Bulgaria
³Department of Health Policy and Management, Faculty of Public Health, Medical University of Sofia, 15 Akademik Ivan Evstratiev Geshov Boulevard, 1431 Sofia, Bulgaria
⁴Department of Pharmaceutical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria, 15A Vasil Aprilov Street, 4002 Plovdiv, Bulgaria -
EXPLORING THE OPINION ABOUT JOB SATISFACTION, LIFELONG LEARNING OPPORTUNITIES AND INSTITUTIONAL SUPPORT AMONG ROMANIAN PHARMACISTS
IOAN ANTOFIE 1, MAGDALENA IORGA 2,3*, LAVINIA-MARIA POP 3, MOHAMMAD JARADAT-HADI 1
1Faculty of Economics, “Valahia” University of Târgoviște, 13 Sinaia Street, 130004, Târgoviște, Romania
2Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy of Iași, 16Universității Street, 700115, Iași,
Romania
3Faculty of Psychology and Educational Sciences, “Alexandru Ioan Cuza” University of Iași, Carol Boulevard, 700506, Iași, Romania -
PERCEPTIONS OF FRONTLINE HEALTHCARE PROFESSIONALS ON COVID-19 VACCINATION
RALUCA ELISABETA LUPAȘCU (MOISI) 1, PAVEL CĂLIN COBELSCHI 2*, MARIA DORINA CRĂCIUN 3, DANIELA PIȚIGOI 3,4, VICTORIA ARAMĂ 4,5, CĂTĂLIN GABRIEL APOSTOLESCU 4,5, MARINA IONELA ILIE 1, ANDREEA LETIȚIA ARSENE 1
1Department of General and Pharmaceutical Microbiology, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 020956, Bucharest, Romania
2Faculty of Medicine, Transilvania University, 500036, Brașov, Romania
3Department of Epidemiology 1, “Carol Davila” University of Medicine and Pharmacy, 020021, Bucharest, Romania
4“Prof. Dr. Matei Balș” National Institute for Infectious Diseases, 021105, Bucharest, Romania
5Department of Infectious Diseases 1, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania