Romanian Society of Pharmaceutical Sciences

« Back to Farmacia Journal 4/2022

RECENT ADVANCES IN THE STUDY OF DERIVATIVES OF (EZ)-N’- BENZYLIDENE-(2RS)-2-(6-CHLORO-9H-CARBAZOL-2-YL) PROPANOHYDRAZIDE

ALEXANDRA TEODORA (TELEHOIU) BORDEI 1, CARMEN LIMBAN 1*, DIANA CAMELIA
NUȚĂ 1, IRINA ZARAFU 2, ELEONORA DENES 3, LUMINIȚA MĂRUȚESCU 4,5, MARIANA CARMEN CHIFIRIUC 4,5,6, MARCELA POPA 4,5, CORINA ARAMĂ 1

1Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia, 020956, Bucharest, Romania 2Faculty of Chemistry, University of Bucharest, 4-12 Regina Elisabeta, 030018 Bucharest, Romania
3Supramolecular Organic and Organometallic Chemistry Centre, Department of Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, 11 Arany János, 400028 Cluj-Napoca, Romania
4Department of Microbiology and Immunology, Faculty of Biology, University of Bucharest, 91-96 Splaiul Independenței, Bucharest, Romania
5Research Institute of the University of Bucharest, University of Bucharest, 90 Panduri Road, Bucharest, Romania
6Academy of Romanian Scientist, 54 Splaiul Independetei, Bucharest, Romania

Download Full Article PDF

1. Anu K, Suman B, Sunil K, Neha S, Vipin S, Schiff bases: a versatile pharmacophore. J Catal., 2013; 2013: 893512: 1-13. 2. Avram S, Udrea AM, Nuta DC, Limban C, Balea AC, Caproiu MT, Dumitrascu F, Buiu C, Bordei AT, Synthesis and bioinformatic characterization of new Schiff bases with possible applicability in brain disorders. Molecules, 2021; 26(14): 4160: 1-13. 3. Bordei (Telehoiu) AT, Nuță DC, Mușat DG, Missir AV, Căproiu MT, Dumitrașcu F, Zarafu I, Ioniță P, Bădiceanu CD, Limban C, Ozon EA, Microwave assisted synthesis and spectroscopic characterization of some novel Schiff bases of carprofen hydrazide. Farmacia, 2019; 67(6): 955-962. 4. Chakraborty A, Saha C, Podder G, Chowdhury BK, Bhattacharyya P, Carbazole alkaloid with antimicrobial activity from Clausena heptaphylla. Phytochemistry, 1995; 38: 787-789. 5. CLSI. Performance Standards for Antimicrobial Susceptibility Testing. 30th ed. CLSI supplement M100. Wayne, PA: Clinical and Laboratory Standard Institute; 2020. 6. Cuong NM, Wilhelm H, Porzel A, Arnold N, 1-OSubstituted derivatives of murrayafoline A and their antifungal properties. Prod Res., 2008; 22: 1428-1432. 7. Dziedzic A, Kubina R, Wojtyczka RD, Kabała-Dzik A, Tanasiewicz M, Morawiec T, The antibacterial effect of ethanol extract of polish propolis on mutans Streptococci and Lactobacilli isolated from saliva, Evid Based Complement Alternat Med., 2013; 2013: 681891: 1-12. 8. Encio I, Migliaccio M, Martinez V, Synthesis and cytotoxic activity of lipophilic sulphonamide derivatives of the benzo[b]thiophene 1,1-dioxide. Bioorg Med Chem., 2004; 12: 963-968. 9. Guma (Tanasiev) N, Bordei (Telehoiu) AT, Limban C, Sogor C, Manoliu L, Avram S, Bioinformatics and cheminformatics study of carbazole derivatives - p3c7, p3c7-a20 p3c7-s243, and de novo 2,5-disubstituted 1,3,4-oxadiazole derivatives. Farmacia, 2020; 68(4): 665-671. 10. Hagiwara H, Choshi T, Fujimoto H, Sugino E, Hibino S, A novel total synthesis of antibiotic carbazole alkaloid carbazomycin G. Tetrahedron, 2000; 56: 5807-5811. 11. Husain A, Parscha V, Khan SA, Varshney M, Ahmad A, Synthesis and biological evaluation of new hydrazideSchif bases. Bangladesh J Pharmacol., 2015; 10(1): 555-561. 12. Joshi S, Vagdevi H, Vaidya V, Gadaginamath G, Synthesis of new 4-pyrrol-l-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: a novel class of potential antibacterial and antitubercular agents. Eur J Med Chem., 2008; 43: 1989-1996. 13. Mathew B, Vakketh SS, Kumar SS, Synthesis, molecular properties and anthelmintic activity of some Schiff bases of 1,3,4 thiadiazole derivatives. Der Pharma Chem., 2010; 2(5): 337-343. 14. Montoia A, Rocha E, Silva LF, Torres ZE, Costa DS, Henrique MC, Lima ES, Vasconcellos MC, Souza RC, Costa MR, Grafov A, Grafova I, Eberlin MN, Tadei WP, Amorim RC, Pohlit AM, Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog. Bioorg Med Chem Lett., 2014; 24(12): 2631- 2634. 15. Murtaza S, Akhtar MS, Kanwal F, Abbas A, Ashiq S, Shamim S, Synthesis and biological evaluation of Schiff bases of 4-aminophenazone as an antiinflammatory, analgesic and antipyretic agent. J Saudi Chem Soc., 2017; 21(1): S359-S372. 16. Nayak GS, Poojary B, Synthesis of novel Schiff bases containing arylpyrimidines as promising antibacterial agents. Heliyon, 2019; 5(8): E02318 17. Pandey S, Lakshmi V, Pandey A, Biological activity of Mannich bases. Indian Pharm Sci., 2003; 65: 213-222. 18. Patel OPS, Mishra A, Maurya R, Saini D, Pandey J, Taneja I, Raju KSR, Kanojiya S, Shukla SK, Srivastava MN, Wahajuddin M, Tamrakar AK, Srivastava AK, Yadav PP, Naturally occurring carbazole alkaloids from Murraya koenigii as potential antidiabetic agents. J Nat Prod., 2016; 79(5): 1276-1284. 19. Patrinoiu G, Calderón-Moreno JM, Chifiriuc CM, Saviuc C, Birjega R, Carp O, Tunable ZnO spheres with high anti-biofilm and antibacterial activity via a simple green hydrothermal route. J Colloid Interface Sci., 2016; 462: 64-74. 20. Pollo LAE, Martin EF, Machado VR, Cantillon D, Wildner LM, Bazzo ML, Waddell SJ, Biavatti MW and Sandjo LP, Search for Antimicrobial Activity Among Fifty-Two Natural and Synthetic Compounds Identifies Anthraquinone and Polyacetylene Classes That Inhibit Mycobacterium tuberculosis. Front Microbiol., 2021; 11: 622629: 1-11. 21. Prodan AM, Iconaru SL, Chifiriuc CM, Bleotu C, Ciobanu CS, Motelica-Heino M, Sizaret S, Predoi D, Magnetic properties and biological activity evaluation of iron oxide nanoparticles. J Nanomater., 2013; 2013: 893970: 1-7. 22. Rajakumar P, Sekar K, Shanmugaiah V, Mathivanan N, Synthesis of novel carbazole based macrocyclicamides as potential antimicrobian agents. Eur J Med Chem., 2009; 44: 3040-3045. 23. Ruegg UT, Burgess GM, Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Trends Pharmacol Sci., 1989; 10: 218-220. 24. Sahoo A, Swain SS, Behera A, Sahoo G, Mahapatra PK, Panda SK, Antimicrobial peptides derived from insects offer a novel therapeutic option to combat biofilm: A review. Front Microbiol., 2021; 12: 661195: 1-29. 25. Shaheen MA, Feng S, Anthony M, Tahir MN, Hussan M, Seo SY, Ahmad S, Iqbal M, Saleem M, Lu C, Metal-based scaffolds of Schiff bases derived from naproxen: synthesis, antibacterial activities, and molecular dockinh studies. Molecules, 2019; 24(7): 1237: 1-12. 26. Sharma D, Kumar N, Pathak D, Synthesis, characterization and biological evaluation of some newer carbazole derivatives. J Serb Chem Soc., 2014; 79(2): 125-132. 27. The United States Pharmacopeial Convention, with Supliment, USP 30, Washington D.C., 2007. 28. Vandana J, Munira M, Laddha K, Murraya Koenigii: An updated review. J Ayu Her Med., 2012; 2(4): 607-627. 29. Venugopal K, Jayashree B, Microwave-induced synthesis of Schiff bases of aminothiazolylbromocoumarins as antibacterials. Indian J Pharm Sci., 2008; 70: 88-91. 30. XcaliburTM Software, Thermo Fisher Scientific, 168 3rd Avenue, Waltham, MA USA, www.thermofisher.com. 31. Zarafu I, Pătrașcu B, Măruțescu L, Bleotu C, Limban C, Tatibouët A, Chifiriuc MC, Nuță DC, Ioniță P, Bioevaluation of the antimicrobial and anti-proliferative potential of some derivatives of 3,5-dinitro-4methoxyamino-benzoic acid. Farmacia, 2020; 68(1): 8-14. 32. Zhang FF, Gan LL, Zhou CH, Synthesis, antibacterial and antifungal activities of some novel carbazole derivatives. Bioorg Med Chem., 2010; 20: 1881-1884.