Farmacia Journal 4/2017
Volume 65 | Number 4 | Year 2017
Download this issue’s covers and announcements.
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LC-MS/MS ESI METHODS FOR THE DETERMINATION OF OESTROGENS AND ANDROGENS IN BIOLOGICAL MATRIX – A MINIREVIEW
IBOLYA FÜLÖP, CAMIL-EUGEN VARI*, AMALIA MIKLOS, SILVIA IMRE
Faculty of Pharmacy, University of Medicine and Pharmacy Tîrgu Mureş, 38 Gheorghe Marinescu Street, 540139, Târgu Mureş, Romania
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SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW N-(2-DIMETHYLAMINOETHYL)-N-((UN)SUBSTITUTED PHENYL-2-(4-METHYL/METHOXY-PHENOXYMETHYL)BENZAMIDES
HOREA GURGU 1, DIANA CAMELIA NUŢĂ 1*, MIRON TEODOR CĂPROIU 2, CONSTANTIN DRĂGHICI 2, MARIANA CARMEN CHIFIRIUC 3, ALEXANDRU VASILE MISSIR 1, CARMEN LIMBAN 1
1.Pharmaceutical Chemistry Department, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
2 .“Costin D. Nenițescu” The Organic Chemistry Centre of Romanian Academy, 202B Splaiul Independenței Street, 77208, Bucharest, Romania
3 .Department of Botanic- Microbiology, Faculty of Biology, University of Bucharest, Research Institute of University of Bucharest - ICUB, 91-95 Splaiul Independenței Street, Bucharest, Romania -
SYNTHESIS AND ANTIMICROBIAL ACTIVITY EVALUATION OF SOME NEW 2-(3-PYRIDIL)-THIAZOLYL-1,3,4-OXADIAZOLINES
SMARANDA DAFINA ONIGA 1, CĂTĂLIN ARANICIU 1*, CRISTINA IOANA STOICA 1, MARIANA DOINA PALAGE 1, LAURIAN VLASE 2, ADRIAN PIRNAU 3, LUMINIȚA MARUȚESCU 4,5, MARIANA CARMEN CHIFIRIUC 4,5, OVIDIU ONIGA 6
1.“Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Therapeutic Chemistry, 12 Ion Creangă Street, 400010, Cluj-Napoca, Romania
2 .“Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, 41 Victor Babeș Street, 400012, Cluj-Napoca, Romania
3 .National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donat Street, 400293, Cluj-Napoca, Romania
4 .University of Bucharest, Faculty of Biology, Department of Microbiology, 1-3 Portocalelor Street, 60101, Bucharest, Romania
5 .Research Institute of the University of Bucharest - ICUB, 91-95 Independenței Street, Bucharest, Romania
6 .“Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 41 Victor Babeș Street, 400012, Cluj-Napoca, Romania -
BIOLOGICAL EVALUATION OF CHITOSAN-ANTIDIABETIC DRUG FORMULATIONS FOR THE TREATMENT OF DIABETES MELLITUS
FLORENTINA GIANINA LUPAŞCU 1, IUSTINA AVRAM 1, LUMINIŢA CONFEDERAT 1, SANDRA MĂDĂLINA CONSTANTIN 1, CRISTINEL IONEL STAN 2*, ELENA CĂTĂLINA LUPUŞORU 3, ALEXANDRU SAVA 1, LENUŢA PROFIRE 1
1.Department of Pharmaceutical Chemistry, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universităţii Street, 700115, Iaşi, Romania
2 .Department of Morphofunctional Science I, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universităţii Street, 700115, Iaşi, Romania
3 .Department of Morphofunctional Science II, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universităţii Street, 700115, Iaşi, Romania -
Fe3O4/SALICYLIC ACID MAGNETIC NANOPARTICLES DELIVERY ROUTE. A SIMPLE METHOD FOR TISSUE TARGETING
ADELA-LUIZA CHIRILĂ 1, ION MÎNDRILĂ 1*, DAN EDUARD MIHAIESCU 2, BOGDAN MÎNDRILĂ 1, CRISTINA PREDOI 1, OVIDIU MARCEL MĂRGINEAN 1, IONICA PIRICI 1, GABRIELA RĂU 3, ALICE SANDRA BUTEICĂ 3
1.Morphological Sciences Department, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Craiova, Romania
2 .“Costin Nenițescu” Department of Organic Chemistry, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, Bucharest, Romania
3 .Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, Romania -
HPLC STUDIES FOR ASSESSING THE STABILITY OF CARVEDILOL TABLETS
ANNE-MARIE CIOBANU 1#, ANCA LUCIA POP 1#*, SIMONA CRIŞAN 2#, MARIANA PALI 2#, GEORGE TRAIAN ALEXANDRU BURCEA-DRAGOMIROIU 1#, DANIELA ELENA POPA 1#, DUMITRU LUPULIASA 1#, MARIA BÂRCĂ 1#
1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, Bucharest, Romania
2 .“AC HELCOR” Pharmaceutical Company, R&D Centre, 6 Victor Babeş Street, Baia Mare, Romania -
IN VITRO EFFECTS OF FLUOXETINE AND NORFLUOXETINE ON BREAST CANCER PROLIFERATION
DIANA LUPU #, ANCA POP #, IONEL FIZEȘAN *, BELA KISS, FELICIA LOGHIN
“Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Toxicology, Cluj-Napoca, Romania
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IRBESARTAN DISSOLUTION ENHANCEMENT USING PEG-BASED SOLID DISPERSIONS: THE EFFECT OF PEG MOLECULAR WEIGHTS
NOUSHIN BOLOURCHIAN *, FATEMEH MIRZAYEH FASHAMI, SEYED MOHSEN FOROUTAN
Department of Pharmaceutics and Pharmaceutical Nanotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
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STUDIES ON THE INFLUENCE OF AMIODARONE COMPLEXATION WITH CYCLODEXTRIN DERIVATIVES ON THE IN VITRO RELEASE FROM MATRIX TABLETS
ANDREEA CREȚEANU 1, LĂCRĂMIOARA OCHIUZ 1*, CORNELIA VASILE 2, MĂDĂLINA VIERIU 1, GLADIOLA ŢÂNTARU 1
1.Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 15 Universității Street, 700115, Iași, Romania
2 .“Petru Poni” Institute of Macromolecular Chemistry, 41A Grigore Ghica Vodă Alley, 700487, Iași, Romania -
DIETARY OMEGA-3 FATTY ACIDS SUPPLIMENTATION FOR ATTENTION DEFICIT WITH HYPERACTIVITY DISORDER IN EPILEPTIC CHILDREN
OANA TARŢA-ARSENE 1#*, MĂDĂLINA LEANCA 1#, ALICE DICĂ 1#, EMA BRAN 1#, FLORINA RAD 1#, OLIVIA TIMNEA 2#, DANIELA PĂCURAR 3#, BRUNO ȘTEFAN VELESCU 4#, ALINA CRENGUȚA NICOLAE 5#, CRISTINA MANUELA DRĂGOI 5#
1.Department of Pediatric Neurology, “Al. Obregia” Clinical Hospital, 10 Berceni Street, 041914, Bucharest, Romania
2 .Physical and Sport Faculty, Ecological University of Bucharest, Romania
3 .“Grigore Alexandrescu” Clinic Paediatric Emergency Hospital, Bucharest, Romania
4 .Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, Bucharest, 020956, Romania
5 .Department of Biochemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, Bucharest, 020956, Romania -
THE INFLUENCE OF SERTRALINE ON THE PHARMACOKINETICS OF CARVEDILOL. A PRECLINICAL STUDY ON RATS
MARIA BIANCA ABRUDAN 1, DANA MARIA MUNTEAN 1*, MARIA ADRIANA NEAG 2, LAURIAN VLASE 1, ANA-MARIA GHELDIU 1
1.Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș Street, RO-400012, Cluj-Napoca, Romania
2 .Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș Street, RO-400012, Cluj-Napoca, Romania -
ISOBOLAR ANALYSIS OF THE BINARY FIXED-RATIO COMBINATION OF ACETYLSALICILIC ACID-ACETAMINOPHEN
VERONICA BILD 1,2,4, DANIELA CARMEN ABABEI 1*, MONICA NEAMȚU 1, ALEXANDRU VASINCU 1, WALTHER BILD 2,3, GABRIELA DUMITRIȚA STANCIU 4, BOGDAN IONEL TAMBA 4, GHEORGHE SOLCAN 5, SORIN BEȘCHEA CHIRIAC 5
1.“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy, Pharmacodynamics and Clinical Pharmacy Department, Iași, Romania
2 .Center of Biomedical Research of the Romanian Academy, Iași, Romania
3 .“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, Physiology Department, Iași, Romania
4 .“Grigore T. Popa” University of Medicine and Pharmacy, CEMEX Department, Iași, Romania
5 .“Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine, Faculty of Veterinary Medicine, Iași, Romania -
EFFECT OF FUCOIDAN, HABERLEA RHODOPENSIS AND PROPOLIS ON MOBILIZATION OF THE CD34+ STEM CELLS IN RATS
ELISAVETA G. APOSTOLOVA 1*, VESELA KOKOVA 1, ZHIVKO PEYCHEV 2, STELA PEYCHEVA 3, APOSTOL APOSTOLOV 4
1.Department of Pharmacology and Drug Toxicology, Faculty of Pharmacy, Medical University, Plovdiv, Bulgaria
2 .Department of Medical Informatics, Biostatistics and Interactive Education, Faculty of Public Health, Medical University, Plovdiv, Bulgaria
3 .Department of Paediatric Dentistry, Faculty of Dental Medicine, Medical University, Plovdiv, Bulgaria
4 .Department of Anaesthesiology and Intensive Care, “St. George” University Hospital, Plovdiv, Bulgaria -
POLYGONUM BISTORTA L. HERBA ET FLORES. POLYPHENOLS PROFILE, ANTIOXIDANT PROPERTIES AND CYTOTOXIC EFFECT ON MURINE FIBROBLAST CELL LINE NIH3T3
LUCIA PÎRVU 1, FAWZIA SHA’AT 2,3*, LUMINIȚA CLAUDIA MICLEA 2, TUDOR SAVOPOL 2, GEORGETA NEAGU 1, DENISA IOANA UDEANU 4, MIHAELA GEORGETA MOISESCU 2
1.National Institute for Chemical - Pharmaceutical Research and Development (INCDCF), 112 Vitan Road, 031299, Bucharest, Romania
2 .“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, Biophysics and Cellular Biotechnology Department, 8 Eroii Sanitari Boulevard, 050474, Bucharest, Romania
3 .Politehnica University of Bucharest, Faculty of Applied Chemistry and Material Science, Analytical Chemistry and Environmental Engineering Department, 1-7 Gheorghe Polizu Street, 011061, Bucharest, Romania
4 .“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Clinical Laboratory and Food Safety, 6 Traian Vuia Street, 020956, Bucharest, Romania -
DRY ROSE PETAL EXTRACTS AND COMPRESSED LOZENGES: FORMULATION AND NIR – CHEMOMETRIC QUANTIFICATION OF ACTIVE PRINCIPLES
ALEXANDRU GAVAN 1*, ANCA MARIA TOIU 2, MIRCEA TAMAȘ 3 IOAN TOMUȚĂ 1
“Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Cluj-Napoca, Romania
1 .Department of Pharmaceutical Technology and Biopharmaceutics,
2 .Department of Pharmacognosy,
3 .Department of Pharmaceutical Botany -
EVALUATION OF POLYQUATERNIUM-1 EFFECTS ON HUMAN CORNEAL EPITHELIAL CELLS
RUI WANG 1, YUJIA ZHAO 2, YANG JIAO 3, XIAOHUA LI 1*
1.Department of Ophthalmology, Hong Qi Hospital of Mu Dan Jiang Medical University, Mu Dan Jiang City, 157011, China
2 .College of Pharmacy, Mu Dan Jiang Medical University, Mu Dan Jiang City, 157011, China
3 .Department of Neurology 1, Hong Qi Hospital of Mu Dan Jiang Medical University, Mu Dan Jiang City, 157011, China -
CHEMICAL COMPOSITION OF THE VOLATILE OILS FROM THE FRUITS AND SEEDS OF THE MEDICINAL PLANT PYCNOCYCLA AUCHERANA DECNE. EX BOISS. FROM IRAN
FARZANEH ALIMIRZALOO 1, JINOUS ASGARPANAH 2*
1.Department of Phytochemistry and Essential Oil Technology, Faculty of Pharmaceutical Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran
2 .Department of Pharmacognosy, Faculty of Pharmacy, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran -
THE INFLUENCE OF A NEW RUTIN DERIVATIVE IN AN EXPERIMENTAL MODEL OF INDUCED HYPERHOMOCYSTEINEMIA IN RATS
CRISTIANA FILIP 1, ELENA ALBU 2*, DAN LUPAȘCU 3, NINA FILIP 1
“Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania
1 .Department of Biochemistry,
2 .Department of Pharmacology,
3 .Department of Pharmaceutical Chemistry -
EFFICACY OF TIGECYCLINE TREATMENT IN SEVERE AND COMPLICATED CLOSTRIDIUM DIFFICILE INFECTION
LILIANA MIREA 1,2#, CORNELIA NIȚIPIR 2,3#*, IOANA CRISTINA GRINȚESCU 1#, ALEXANDRU BĂETU 1#, RALUCA GÎNGU 4#, ANDREEA LETIȚIA ARSENE 5#, IOANA MARINA GRINȚESCU 1,2#
1.Intensive Care Clinic, Clinical Emergency Hospital of Bucharest, Romania
2 .“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
3 .Department of Oncology and Radiotherapy, Elias Emergency University Hospital, Bucharest, Romania
4 .Department of Microbiology, Clinical Emergency Hospital of Bucharest, Romania
5 .“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of General and Pharmaceutical Microbiology, Bucharest, Romania -
DETERMINATION OF ROSMARINIC ACID BY HPTLC-IMAGE ANALYSIS IN MEDICINAL TEAS AND THEIR BIOLOGICAL PROPERTIES
DANIELA BENEDEC #, ILIOARA ONIGA*, ANNAMARIA KOZMA-IMRE, DANIELA HANGANU, VIORICA ȚĂRMURE #, EDE BODOKI
“Iuliu Hațieganu” University of Medicine and Pharmacy, 8 V. Babeș Street, Cluj-Napoca, Romania
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PHARMACOKINETIC CHARACTERISTICS OF VANCOMYCIN IN THE TREATMENT OF CRITICALLY ILL PATIENTS WITH PULMONARY INFECTIONS
QINGXIA ZHENG 1, LIPING LIU 1, XIAOWEI MA 1, RUI YANG 1*
1.Critical Care Medicine, Hongqi Hospital of Mudanjiang Medical University, MuDanjiang City, 157011, China
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GAMMA-GLUTAMYL TRANSPEPTIDASE ALTERATION AS A BIOMARKER OF OXIDATIVE STRESS IN PATIENTS WITH HUMAN PAPILLOMAVIRUS LESIONS FOLLOWING TOPICAL TREATMENT WITH SINECATECHINS
ILINCA NICOLAE 1#, MIRCEA TAMPA 1,2#*, CRISTINA MITRAN 1#, CORINA DANIELA ENE 3#, MĂDĂLINA MITRAN 1#, CLARA MATEI 2#, ALINA MUŞETESCU 1#, SILVIU PIȚURU 2#, CORINA SILVIA POP 4#, SIMONA-ROXANA GEORGESCU 1,2#
1.“Victor Babeş” Clinical Hospital for Infectious Diseases, Bucharest, Romania
2 .“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
3 .“Carol Davila” Nephrology Hospital, Bucharest, Romania
4 .Emergency University Hospital, Bucharest, Romania -
INVESTIGATION OF ANTIOXIDANT AND ANTIMICROBIAL POTENTIAL OF SOME EXTRACTS FROM HEDERA HELIX L.
CARMEN ELENA POP 1#, MARCEL PÂRVU 2#, ANDREEA LETIȚIA ARSENE 3#*, ALINA ELENA PÂRVU 4#, DAN CRISTIAN VODNAR 5#, MONICA TARCEA 6#, ANCA MARIA TOIU 7#, LAURIAN VLASE 8#
1.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Drug Industry and Pharmaceutical Biotechnology, 8 Victor Babeș Street, Cluj-Napoca, Romania
2 .“Babeș - Bolyai” University, Faculty of Biology and Geology, Department of Biology, 42 Republicii Street, Cluj-Napoca, Romania
3 .“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of General and Pharmaceutical Microbiology, 6 Traian Vuia Street, District 2, Bucharest, Romania
4 .“Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Medicine, Department of Pathophysiology, 3 Victor Babeș Street, Cluj-Napoca, Romania
5 .University of Agricultural Sciences and Veterinary Medicine, Faculty of Food Science and Technology, Department of Food Science, 3-5 Mănăștur Street, Cluj-Napoca, Romania
6 .University of Medicine and Pharmacy, Faculty of Medicine, Department of Community Nutrition and Food Safety, 38 Gheorghe Marinescu Street, Târgu Mureș, Romania
7 .“Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacognosy, 8 Victor Babeș Street, Cluj-Napoca, Romania
8 .“Iuliu Hațieganu” University of Medicine and Pharmacy, Department of Pharmaceutical Technology and Biopharmaceutics, 8 Victor Babeș Street, Cluj-Napoca, Romania -
IN VITRO SPECTROPHOTOMETRIC EVALUATION OF ACRYLIC TEETH STAINING RELATED TO DIETARY AND ORAL ANTISEPTIC AGENTS
RALUCA DRĂGHICI 1, CRISTINA TEODORA PREOTEASA 1*, LĂCRĂMIOARA POPA 2, CĂTĂLINA MURARIU-MĂGUREANU 1, ANA MARIA TANCU 1, DANIELA MEGHEA 1, ANCA DIANA CRISTEA 1, ELENA PREOTEASA 1
1.Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2 .Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania -
COMPARATIVE STUDY BETWEEN THE SALES OF ANTIULCER DRUGS H2 ANTAGONISTS AND PROTON PUMP INHIBITORS
ANAMARIA BOBOIA 1*, LAVINIA ALEXANDRA FEHER 1, STANCA CUC 2, MARIOARA MOLDOVAN 2
1.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Pharmaceutical Management, Marketing and Legislation Department, 8 Victor Babeş St., 400012, Cluj-Napoca, Romania
2 .“Babeş-Bolyai” University, “Raluca Ripan“ Institute for Research in Chemistry, 30 Fântânele St., 400294, Cluj-Napoca, Romania