Farmacia Journal 4/2016

Volume 64 | Number 4 | Year 2016

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CHEMOTHERAPY-INDUCED CARDIOTOXICITY IN ONCOLOGY DRUGS INVOLVED AND CLINICAL ASSESSMENT

SIMONA SORANA CĂINAP^1,2, VIORICA NAGY^1,3, CĂLIN CĂINAP^1,3*

1.University of Medicine and Pharmacy, 8 Victor Babeş Street, 400012 Cluj-Napoca, Romania
2.Emergency County Hospital for Children, 68 Moților Street, 400370, Cluj-Napoca, Romania
3.Institute of Oncology “I. Chiricuță”, 34 - 36 Republicii Street, 400015, Cluj-Napoca, Romania

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THE EFFECT OF NIMODIPINE ON A RAT MODEL OF PACLITAXEL – INDUCED PERIPHERAL NEUROPATHY

IONUȚ COSMIN CIOTU¹, DUMITRU LUPULIASA², CRISTINA ELENA ZBÂRCEA^1*, SIMONA NEGREȘ¹

1.Pharmacology and Clinical Pharmacy Department, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Traian Vuia no 6, 020956, Bucharest, Romania
2.Pharmaceutical Technology Department, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Traian Vuia no 6, 020956, Bucharest, Romania

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POLYPHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF CHRYSANTHEMUM PARTHENIUM EXTRACT

DANIELA HANGANU ^1#, DANIELA BENEDEC ^1#, LAURIAN VLASE^1*, IULIA POPICA¹, CONSTANTIN BELE², OANA RAITA³, ANA-MARIA GHELDIU¹, CIPRIAN VALENTIN MIHALI⁴, VIORICA ȚĂRMURE¹

1.“Iuliu Hatieganu” University of Medicine and Pharmacy, 8 V. Babes Street, Cluj-Napoca, Romania
2.University of Agricultural Sciences and Veterinary Medicine, 3-5 Mănăştur Street, Cluj-Napoca, Romania
3.National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath Street, Cluj-Napoca, Romania
4.Institute of Life Sciences, “Vasile Goldiş” Western University, 86 L. Rebreanu Street, Arad, Romania

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ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF PHYLLOPHORA PSEUDOCERANOIDES (GMELIN) NEW. ET TAYL

ADRIANA TRIFAN^1*, DACIANA SAVA², LAURA ADRIANA BUCUR³, COSMIN TEODOR MIHAI⁴, ANA CLARA APROTOSOAIE¹, OANA CIOANCĂ¹, MONICA HĂNCIANU¹, ANCA MIRON¹

1.Department of Pharmacognosy, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universitatii Street, 700115, Iasi, Romania
2.Department of Natural Sciences, Faculty of Natural and Agricultural Sciences, “Ovidius” University Constanta, 1 Universitatii Street, Campus, Building B, 900470, Constanta, Romania
3.Department of Pharmacognosy, Faculty of Pharmacy, “Ovidius” University Constanta, 1 Universitatii Street, Campus, Building B, 900470, Constanta, Romania
4.Interdisciplinary Research Department-Field Science, “Alexandru Ioan Cuza” University of Iasi, 11 Carol I Bd., 700506 Iasi, Romania

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INTRAVENOUS LEVETIRACETAM AS SECOND LINE OPTION FOR STATUS EPILEPTICUS

AURELIAN UNGUREANU¹, LUCA LIVIU RUS^2*, FELICIA GABRIELA GLIGOR², ANA LĂZĂROAE¹, LIIANA PRODAN¹, CORINA ROMAN-FILIP^1,3

1.Department of Neurology, Academic Emergency Hospital Sibiu, 2-4 Pompeiu Onofreiu Street, 550166, Sibiu, Romania
2.Preclinical Department, Faculty of Medicine, “Lucian Blaga” University, 2A Lucian Blaga Street, 550169, Sibiu, Romania
3.Department of Neurology, Faculty of Medicine, “Lucian Blaga” University, 2A Lucian Blaga Street, 550169, Sibiu, Romania

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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF PHENYLSELENYL TRIBROMIDE AND ITS FUSED THIENOPYRIMIDINE DERIVATIVES

BORIS M. SHARGA^1*, ANDRIJ O. KRIVOVJAZ¹, MIKHAILO V. SLIVKA¹, LARISA M. LAMBRUCH², ANTONINA V. CHEYPESH², VASIL G. LENDEL¹, VITALY I. NIKOLAYCHUK¹, VLADIMIR P. MARKOVICH²

1.Uzhgorod National University, 3 Narodna Sq., 88000, Uzhgorod, Ukraine
2.Regional Station of Sanitary and Epidemiology, 96 Sobranеtska Str., 88000, Uzhgorod, Ukraine

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EDDP METABOLITE AS BIOMARKER FOR MONITORING OF METHADONE SUBSTITUTION TREATMENT

DANIELA BACONI¹, GABRIELA POPESCU¹, ANNE-MARIE CIOBANU^1*, MIRIANA STAN¹, ANA MARIA VLĂSCEANU¹, CRISTIAN BĂLĂLĂU²

1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, Bucharest, Romania
2.“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, Sf. Pantelimon Emergency Hospital, 340 - 342 Pantelimon Avenue, Bucharest, Romania

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GERANYLGERANYLACETONE REDUCES RADIATION-INDUCED DEGENERATION OF SEMINIFEROUS EPITHELIUM IN MICE

BOGDAN HORAŢIU ŞERB¹, ALINA ORMENIŞAN^2*, VLAD PRELUCA¹, MIHAELA CERNUŞCĂ-MIŢARIU¹, MIHAI IOAN MIŢARIU¹

1.Faculty of Medicine, Lucian Blaga University of Sibiu, 2A Lucian Blaga Street, 550169, Sibiu, Romania
2.Department of Oro-Maxillo-Facial Surgery, Târgu-Mureș University of Medicine and Pharmacy, Târgu-Mureș, Romania

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ANTIOXIDANT EVALUATION OF SOME COUMARIN DERIVATIVES

GABRIELA TATARINGA¹, CATALINA STAN^2*, CORNELIA MIRCEA³, ALEXANDRA JITAREANU¹, ANA-MARIA ZBANCIOC¹

1.Department of Organic Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy “Gr. T. Popa” Iasi, Romania
2.Department of Pharmaceutical Industry, Faculty of Pharmacy, University of Medicine and Pharmacy “Gr. T. Popa” Iasi, Romania
3.Department of Pharmaceutical Biochemistry and Clinical Pharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Gr. T. Popa” Iasi, Romania

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ACUTE POSTOPERATIVE PAIN AND ANALGESICS CONSUMPTION IN ORAL AND MAXILLOFACIAL SURGERY

IRINA CAZACU^1*, DANIEL-CORNELIU LEUCUTA², MIHAELA BACIUT³, GRIGORE BACIUT³, CRISTINA MOGOSAN¹, FRANÇOISE HARAMBURU⁴, ANNIE FOURRIERRÉGLAT⁵, FELICIA LOGHIN⁶

1.Department of Pharmacology, Physiology and Pathophysiology, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca 400012, Romania
2.Department of Medical Informatics and Biostatistics, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca 400012, Romania
3.Department of Maxillofacial Surgery and Implantology, Faculty of Dentistry, Clinic of Oral and Maxillofacial Surgery, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca 400012, Romania
4.Regional Pharmacovigilance Centre, CHU de Bordeaux, INSERM U657, Department of Pharmacology, Bordeaux 33000, France
5.University of Bordeaux, INSERM U657, Department of Pharmacology, Bordeaux 33000, France
6.Department of Toxicology, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca 400012, Romania

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ORDERED MESOPOROUS CARBON BASED SENSOR FOR SENSITIVE DETECTION OF VITAMIN B6 IN PHARMACEUTICALS

IRINA MIRELA APETREI¹, CONSTANTIN APETREI^2*, OLIMPIA DUMITRIU BUZIA¹

1.Department of Pharmaceutical Sciences, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University of Galati, Romania
2.Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunarea de Jos” University of Galati, Romania

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1,2,4-TRIAZOLES AS INTERMEDIATES FOR THE SYNTHESIS OF HYBRID MOLECULES

GEORGETA ŞERBAN^*

University of Oradea, Faculty of Medicine and Pharmacy, Pharmaceutical Chemistry Department, 29 Nicolae Jiga, 410028 Oradea, România

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COMPUTATIONAL SEARCH FOR LONG BONDS IN RADICAL CATIONS OF SUGARS 1. GLUCOFURANOSE, GALACTOFURANOSE AND MANNOFURANOSE DI-O-ISOPROPYLIDENE DERIVATIVES

MIHAI-COSMIN PASCARIU¹, MADIAN RAFAILĂ², MIHAI MEDELEANU², VALENTIN BADEA², ALEXANDRA TEODORA GRUIA³, VICTOR LORIN PURCAREA⁴, MIRCEA PENESCU^4,5, EUGEN SISU^6*

1.“Vasile Goldiş” Western University of Arad, Faculty of Pharmacy, 86 Liviu Rebreanu, 310045, Arad, Romania
2.University Politehnica Timişoara, Faculty of Industrial Chemistry and Environmental Engineering, 6 Carol Telbisz,
300001, Timişoara, Romania
3.Clinical County Hospital of Timișoara, Immunology of Transplant Department, 10 Iosif Bulbuca Blvd., 300736, Timişoara,
Romania
4.“Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu, 020021, Bucharest, Romania
5.“Carol Davila” Hospital of Nephrology, 4 Calea Griviței, 010731, Bucharest, Romania
6.“Victor Babeş” University of Medicine and Pharmacy of Timișoara, Faculty of Medicine, 2 Eftimie Murgu Sq., 300041,
Timișoara, Romania

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STUDIES ON XANTHINE DERIVATIVES (II). SYNTHESIS AND ANTIOXIDANT EFFECTS OF SOME HYDRAZONES WITH XANTHINE STRUCTURE

SANDRA CONSTANTIN¹, FREDERIC BURON², SYLVAIN ROUTIER², LUMINIȚA CONFEDERAT¹, ANDREEA TEODORA IACOB¹, ANCA MIRON¹, LENUȚA PROFIRE^1*

1.University of Medicine and Pharmacy ”Grigore. T. Popa” Iași, Faculty of Pharmacy, Universității Street, no. 16, 700115, Iași, Romania
2.University of Orleans, CNRS, Institut de Chimie Organique et Analytique, UMR 7311, Rue de Chartres BP 6759, F-45067 Orléans, France

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DEVELOPMENT OF GASTRORETENTIVE FLOATING TABLETS OF DILTIAZEM HYDROCHLORIDE AND ITS STATISTICAL OPTIMIZATION

VENKATA SRIKANTH MEKA^*, KOHILA VANI A/P J GUDY, RAVI SHESHALA

School of Pharmacy, International Medical University, Kuala Lumpur-57000, Malaysia

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MINERAL ELEMENTS PROFILE, BIOACTIVE COMPOUNDS AND ANTIOXIDANT CAPACITY OF WILD BLUEBERRY AND OF PHARMACEUTICAL PREPARATIONS FROM BLUEBERRY (VACCINIUM MYRTILLUS)

TÜNDE JURCA¹, LAURA VICAȘ^1*, IMRE TÓTH², MIHÁLY BRAUN³, ELEONORA MARIAN¹, ALIN TEUSDEA⁴, SIMONA VICAȘ⁴, MARIANA MUREȘAN¹

1.University of Oradea, Medicine and Pharmacy Faculty, Department Pharmacy, 1 Universitatii Square, Oradea, Romania
2.University of Debrecen, Department of Inorganic and Analytical Chemistry, 1 Egyetem tér Street, Debrecen, Hungary
3.Hungarian Academy of Science, Institute for Nuclear Research, 18/c Bem tér Street, Debrecen, Hungary
4.University of Oradea, Faculty of Environmental Protection, 26 General Magheru Street, Oradea, Romania

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EFFECTS OF OXIDATIVE STRESS AND PHARMACOLOGYCAL TREATMENT ON GERIATRIC SYNDROMES IN THE HOSPITALIZED ELDERLY PATIENTS

ADINA CARMEN ILIE, IOANA DANA ALEXA^*, ANCA IULIANA MOROŞANU, ADRIAN COVIC, VASILE CEPOI

"Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania

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EVALUATION OF THE INGESTION OF PARABENS DURING THE USE OF DENTAL CARE PRODUCTS BY HEALTHY HUMAN VOLUNTEERS

MIRCEA DUMITRU CROITORU, AMALIA MIKLOS^*, ERZSÉBET FOGARASI, MARIA MARGARETA COMAN, IBOLYA FÜLÖP

Department of Toxicology and Biopharmacy,, Faculty of Pharmacy, University of Medicine and Pharmacy of Târgu Mureș, 38 Gheorghe Marinescu Street, 540138, Târgu Mureș, Romania

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FLUOXETINE INFLUENCE ON BODY WEIGHT, SERUM ADIPONECTIN LEVEL AND ADIPOSE TISSUE TRIGLYCERIDES LEVELS IN RATS

MELINDA KOLCSÁR¹, ZSOLT GÁLL^1,2*, ISTVÁN LÓRÁNT BÍRÓ¹, LÁSZLÓ ISTVÁN BÁBA¹, ANNAMARIA IMRE², MARIA T. DOGARU¹, ORSOLYA MÁRTHA³

1.Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy of Tîrgu Mureș, Gh. Marinescu Street, No. 38, Târgu Mureș, Romania
2.Doctoral School, University of Medicine and Pharmacy of Tîrgu Mureș, Gh. Marinescu Street, No. 38, Târgu Mureș, Romania
3.Department of Urology, Faculty of Medicine, University of Medicine and Pharmacy of Tîrgu Mureș, Gh. Marinescu street, No.38, Târgu Mureș, Romania

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AUTOIMMUNE DISORDERS DUE TO DOUBLE ANTIVIRAL THERAPY WITH PEGINTERFERON AND RIBAVIRIN IN PATIENTS WITH HEPATITIS C VIRUS INFECTION

ANCA OANA DOCEA ^1#, ELIZA GOFITA ^1#*, DANIELA CALINA ^2#, ZAHARIE SORIN IOAN ^3#, DANIEL IONICA VALCEA ^4#, PAUL MITRUT ^5#

1.Toxicology Department, University of Medicine and Pharmacy, Faculty of Pharmacy, 2 Petru Rares, 200349, Craiova, Romania
2.Clinical Pharmacy Department, University of Medicine and Pharmacy, Faculty of Pharmacy, 2 Petru Rares, 200349, Craiova, Romania
3.Nephrology Department, University of Medicine and Pharmacy, Faculty of Medicine, 2 Petru Rares, 200349, Craiova, Romania
4.2nd Surgical Department, University of Medicine and Pharmacy, Faculty of Medicine, 2 Petru Rares, 200349, Craiova, Romania
5.Internal Medicine Department, University of Medicine and Pharmacy, Faculty of Medicine, 2 Petru Rares, 200349, Craiova, Romania

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THE SIMULTANEOUS DETERMINATION OF CANDESARTAN, AMLODIPINE AND HYDROCHLOROTHIAZIDE BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY, FROM A MIXTURE AND PHARMACEUTICAL FORMULATIONS

ANCA MOISEI¹, MARIA TOTAN^1*, FELICIA GABRIELA GLIGOR¹, ISABELA CRĂCIUN², NICOLETA TODORAN³, AURELIA ADRIANA CHIŞ¹, DANIELA ELENA POPA⁴

1.“Lucian Blaga” University of Sibiu, Faculty of Medicine, Preclinical Department, 2A Lucian Blaga Street, 550169, Sibiu, Romania
2.Research and Development Centre, Polisano Pharmaceuticals SRL, 156 Alba Iulia Avenue, 550052, Sibiu, Romania
3.University of Medicine and Pharmacy of Târgu-Mureș, Faculty of Pharmacy, Pharmaceutical Technology Department, 38 Gheorghe Marinescu Street, 540139, Târgu Mureș, Romania
4.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Drug Control Department, 6 Traian Vuia Street, 020956, Bucharest, Romania

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IR AND THERMAL CHARACTERIZATION OF NEW SILICOTUNGSTIC ACID COMPLEXES WITH CLEMASTINE AND TIMOLOL

ALEXANDRA FILARETA NEAGU^*, IOANA CLEMENTINA CONSTANTINESCU

“Carol Davila” University of Medicine and Pharmacy Bucharest, Faculty of Pharmacy, Department of Analytical Chemistry, 6th Traian Vuia Street, 020956, Bucharest, Romania

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CODES OF DEONTOLOGY FOR HEALTH PROFESSIONALS – A COMPARATIVE ANALYSIS

OFELIA CRIŞAN^1*, SPERANŢA IACOB²

1.Department of Pharmaceutical Legislation and Management, “Iuliu Haţieganu” University of Medicine and Pharmacy Cluj-Napoca, 12 Ion Creangă Street, Cluj-Napoca, Romania
2.Romanian College of Pharmacists, Cluj Branch, 4 Aurel Vlaicu Street, Cluj-Napoca, Romania

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ANALYSIS OF CARDIOVASCULAR MEDICINES PRICES AND REIMBURSEMENT IN BULGARIA AND ROMANIA

ZORNITSA MITKOVA¹, MARIYA VASILEVA², ALEXANDRA SAVOVA^1,2, MANOELA MANOVA^1,2, GUENKA PETROVA^1*

1.Medical University of Sofia, Faculty of Pharmacy, Bulgaria
2.National Council on Pricing and Reimbursement of medicinal products, Bulgaria

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EPIDEMIOLOGICAL ASPECTS OF TUBERCULOSIS IN ADULTS IN ROMANIA VERSUS THE REPUBLIC OF MOLDOVA

CRISTINA RAIS^1*, ADRIANA ELENA TAEREL¹, EMIL STEFANESCU¹, MIHAIL BRUMĂREL², VLADIMIR SAFTA², STELA ADAUJI², VITALIE PRISCU², VALENTINA SOROCEANU¹

1.Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, Bucharest, Romania
2.“Vasile Procopişin” Department of Social Pharmacy, Faculty of Pharmacy, “Nicolae Testemitanu” State University of Medicine and Pharmacy, 165 Stefan cel Mare si Sfant Street, MD 2004, Chisinau, Republic of Moldova

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