Romanian Society of Pharmaceutical Sciences
 

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MINERAL ELEMENTS PROFILE, BIOACTIVE COMPOUNDS AND ANTIOXIDANT CAPACITY OF WILD BLUEBERRY AND OF PHARMACEUTICAL PREPARATIONS FROM BLUEBERRY (VACCINIUM MYRTILLUS)

TÜNDE JURCA1, LAURA VICAȘ1*, IMRE TÓTH2, MIHÁLY BRAUN3, ELEONORA MARIAN1, ALIN TEUSDEA4, SIMONA VICAȘ4, MARIANA MUREȘAN1

1.University of Oradea, Medicine and Pharmacy Faculty, Department Pharmacy, 1 Universitatii Square, Oradea, Romania
2.University of Debrecen, Department of Inorganic and Analytical Chemistry, 1 Egyetem tér Street, Debrecen, Hungary
3.Hungarian Academy of Science, Institute for Nuclear Research, 18/c Bem tér Street, Debrecen, Hungary
4.University of Oradea, Faculty of Environmental Protection, 26 General Magheru Street, Oradea, Romania

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In this work, we investigated the mineral profile, the bioactive compounds (phenols, flavonoids) content and the antioxidant capacity of wild blueberries and their pharmaceutical preparations (tea, alcoholic extract and capsules). The highest content of phenols and flavonoids was recorded in the alcoholic sample (813.42 ± 15.55 mg GAE- gallic acid equivalent/100 g and 1425.44 ± 1.94 mg QE- quercetin equivalent/100 g), and the highest antioxidant capacity was recorded in fresh blueberries and in the tea derived from these fruits. The mineral elements composition analysis revealed high contents of manganese (8.7956 mg/kg) in the fresh fruits and the antioxidant capacity was strongly linked to the phenols and flavonoid content, as to the content of metals like Zn, Mn and Cu. Our results obtained in this study indicated that the pharmaceutical preparations derived from blueberry have antioxidant potential and high concentrations of bioactive compounds.