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1,2,4-TRIAZOLES AS INTERMEDIATES FOR THE SYNTHESIS OF HYBRID MOLECULES

GEORGETA ŞERBAN^*

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This paper aim was to present some new heterocyclic compounds from the class of 1,2,4-triazole-3-thione which have been synthesized by intramolecular cyclization of the corresponding thiosemicarbazides with ammonia. 4-R-1- cyanoacetylthiosemicarbazides were obtained by nucleophilic addition of cyanoacetic acid hydrazide to different isothiocyanates. The structures of the newly synthesized compounds were elucidated by spectral data and elemental analysis.