Farmacia Journal 5/2017
Volume 65 | Number 5 | Year 2017
Download this issue’s covers and announcements.
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BIOMOLECULAR PROFILE OF COLORECTAL CANCER – THE ROLE OF TELOMERASE AS A POTENT BIOMARKER
JOHN TSIAOUSSIS1, LOUKIA VASSILOPOULOU2, TAXIARCHIS NIKOLOUZAKIS1, VALERII N. RAKITSKII3, ELENI VAKONAKI2, PERSEFONI FRAGIADAKI2, POLYCHRONIS STIVAKTAKIS2, ARISTIDES M. TSATSAKIS4*
1.Laboratory of Anatomy-Histology-Embryology, Medical School, University of Crete, Voutes, 71110, Heraklion, Crete, Greece
2.Laboratory of Toxicology, Medical School, University of Crete, Voutes, 71409, Heraklion, Crete, Greece
3.Federal Scientific Centre of Hygiene, F.F. Erisman, 2, Semashko Street, Mytishchi, Moscow region, 141014, Russia
4.Department of Forensic Sciences and Toxicology, Medical School, University of Crete, Voutes, 71003, Heraklion, Crete,
Greece -
THERAPEUTIC CONSIDERATIONS RELATED TO FINASTERIDE ADMINISTRATION IN MALE ANDROGENIC ALOPECIA AND BENIGN PROSTATIC HYPERPLASIA
ION G. MOTOFEI1#*, DAVID L. ROWLAND2#, DANIELA L. BACONI3#, SIMONA R. GEORGESCU4#, STANA PAUNICĂ4#, VLAD D. CONSTANTIN1#, DENISA BĂLĂLĂU1#, IOANA PAUNICĂ1#, CRISTIAN BĂLĂLĂU1#, CĂTĂLIN BASTON1#, IOANEL SINESCU1#
1.“Carol Davila” University, Faculty of General Medicine, Bucharest, Romania
2.Valparaiso University, Department of Psychology, Valparaiso, Indiana, United States of America
3.“Carol Davila” University, Faculty of Pharmacy, Bucharest, Romania
4.“Carol Davila” University, Faculty of Dentistry, Bucharest, Romania -
POTENTIAL PHARMACEUTICAL USES OF PROBIOTICS AND PREBIOTICS IN OBESITY MANAGEMENT
ADELA CARAMOCI 1*, MIRELA VASILESCU 2, ADRIANA SARAH NICA 3, MIRELA POP 4, EUGENIA ROSULESCU 2, ANCA MIRELA IONESCU 1
1.Departament of Sports Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2.Department of Kinetotherapy and Sports Medicine, University of Craiova, Romania
3.Departament of Rehabilitation, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
4.Mirmed-Aslan Clinic, Bucharest, Romania -
OLANZAPINE TRANSFER INTO SHEEP’S MILK. AN ANIMAL MODEL
BIANCA-EUGENIA ŐSZ 1, AMELIA TERO-VESCAN 2*, MARIA DOGARU 1, SZENDE VANCEA 3, SILVIA IMRE 4, PAUL BOSA 1, CAMIL-EUGEN VARI 1
1.Department of Pharmacology and Clinical Pharmacy, University of Medicine and Pharmacy of Tîrgu Mureș, 38 Gheorghe Marinescu Street, 540139, Târgu Mureș, Romania
2.Department of Pharmaceutical Biochemistry, Chemistry of environmental factors, University of Medicine and Pharmacy of Tîrgu Mureș, Târgu Mureș, Romania
3.Department of Physical Chemistry, University of Medicine and Pharmacy of Tîrgu Mureș, Târgu Mureș, Romania
4.Department of Analytical Chemistry and Drug Analysis, University of Medicine and Pharmacy of Tîrgu Mureș, Târgu Mureș, Romania -
SYNTHESIS AND MOLECULAR DOCKING STUDY OF SOME NEW 1,4-PHENYLENE-BISTHIAZOLES AS FUNGAL LANOSTEROL 14α-DEMETHYLASE INHIBITORS
ANCA-MARIA BORCEA 1*, GABRIEL MARC 1, ADRIAN PÎRNĂU 2, LAURIAN VLASE 1, IOANA IONUŢ 1, BRÎNDUŞA TIPERCIUC 1, OVIDIU ONIGA 1
1.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, 41 Victor Babeş Street, 400012, Cluj-Napoca, Romania
2.National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donath Street, 400293, Cluj-Napoca, Romania -
STUDY DESCRIBING THE FORMULATION AND THE RELEASE OF SOME ACTIVE PHARMACEUTICAL INGREDIENTS FROM HPMC HYDROPHILIC MATRIX TABLETS. NOTE I
GABRIEL ȘARAMET 1#, FLAVIAN ȘTEFAN RĂDULESCU 2#, DALIA SIMONA MIRON 3#, ȘTEFANIA-FELICIA BĂRBUCEANU 4#, ANA ANDREEA STĂNESCU 1#*, LAVINIA VLAIA 5#, SILVIU PIȚURU 6#, DUMITRU LUPULIASA 1#
1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Bucharest, Romania
2.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Drug Industry and Pharmaceutical Biotechnologies, Bucharest, Romania
3.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Pharmaceutical Physics and Informatics, Bucharest, Romania
4.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Organic Chemistry, Bucharest, Romania
5.“Victor Babeș” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology, Timișoara, Romania
6.“Carol Davila” University of Medicine and Pharmacy Bucharest, 37th Dionisie Lupu Street, 020022, Bucharest, Romania -
A NEW ESCULETIN GLYCOSIDE FROM CALENDULA OFFICINALIS (ASTERACEAE) AND ITS BIOACTIVITY
DANIIL N. OLENNIKOV 1*, NINA I. KASHCHENKO 1, CECILE VENNOS 2
1.Institute of General and Experimental Biology, Siberian Division, Russian Academy of Science, Sakh’yanovoy Str., 6, Ulan-Ude, Russia
2.Regulatory and Medical Scientific Affairs, Padma AG, Underfeldstrasse 1, CH-8340, Hinwil, 670047, Switzerland -
RESEARCH REGARDING OBTAINING HERBAL EXTRACTS WITH ANTITUMOUR ACTIVITY. NOTE II. PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT ACTIVITY AND CYTOTOXIC EFFECTS OF CHELIDONIUM MAJUS L., MEDICAGO SATIVA L. AND BERBERIS VULGARIS L. DRY EXTRACTS
CERASELA ELENA GÎRD 1#, LIGIA ELENA DUŢU 1#, TEODORA COSTEA 1#, IOANA NENCU 1#*, MARIA LIDIA POPESCU 1#, TEODORA DALILA BALACI 2#, OCTAVIAN TUDOREL OLARU 3#
1."Carol Davila" University of Medicine and Pharmacy, Faculty of Pharmacy, Pharmacognosy, Phytochemistry and Phytotherapy Department, 6 Traian Vuia Street, 020956, Bucharest, Romania
2."Carol Davila" University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania 3"Carol Davila" University of Medicine and Pharmacy, Faculty of Pharmacy, Pharmaceutical Botany and Cellular Biology Department, 6 Traian Vuia Street, 020956, Bucharest, Romania -
THE INFLUENCE OF RESIDUAL ACETAMINOPHEN ON PHASEOLUS VULGARIS L. SECONDARY METABOLITES
MONICA TĂŞCHINĂ 1#, DANA MARIA COPOLOVICI 1#, SIMONA BUNGĂU 2#, ANDREEA IOANA LUPITU 1#, LUCIAN COPOLOVICI 1#*, CIPRIAN IOVAN 2#
1.“Aurel Vlaicu” University of Arad, Faculty of Food Engineering, Tourism and Environmental Protection, Institute of Research-Development-Innovation in Technical and Natural Sciences, 2 Elena Drăgoi Street, 310330, Arad, Romania
2.University of Oradea, Faculty of Medicine and Pharmacy, 10 Piaţa 1 Decembrie St., 410073, Oradea, Romania -
EFFECT OF ULINASTATIN COMBINED WITH HAEMODIALYSIS ON SEVERE ACUTE PANCREATITIS
HANFEI XING 1, HUI WEN 2*, DUJIE WANG 1, HONGHUI WANG 1, MENG ZHAO 2
1.Department of Thyroid Breast Surgery, Central Hospital of Binzhou City, Binzhou, Shandong, 251700, China
2.Intensive Care Unit, Central Hospital of Binzhou City, Binzhou, Shandong, 251700, China -
NEW SYNTHESIS OF DIPHENYLSULPHONAMIDES COMPOUNDS WITH PHARMACOLOGICAL PROPERTIES. NOTE II
IOANA DANA ROTARU (ENACHE) 1, DIANA CAMELIA NUŢĂ 1*, ILEANA CORNELIA CHIRIŢĂ 1, ALEXANDRU-VASILE MISSIR 1, CARMELLINA DANIELA BĂDICEANU 1, LAURENŢIU MORUŞCIAG 1, MIRON TEODOR CĂPROIU 2, CARMEN LIMBAN 1
1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Bucharest, Romania, 6 Traian Vuia St., 020956, Bucharest, Romania
2.“C. D. Neniţescu” The Organic Chemistry Centre of Romanian Academy, 202B Splaiul Independenţei St., Bucharest, Romania -
SYNERGISTIC EFFECS OT THE DOXEPIN-CANDESARTAN COMBINATION ON THE THERMOALGESIC SENSIBILITY IN MICE
DANIELA CARMEN ABABEI 1, SORIN BEȘCHEA CHIRIAC 5*, WALTHER BILD 2,3, CARMEN SOLCAN 5, ANDREI LUCA 4, RĂZVAN NICOLAE RUSU 1, DELIA BULEA 1, VERONICA BILD 1,2,4
1.“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy, Pharmacodynamics and Clinical Pharmacy Department, Iași, Romania
2.Center of Biomedical Research of the Romanian Academy, Iași, Romania
3.”Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, Physiology Department, Iași, Romania
4.”Grigore T. Popa” University of Medicine and Pharmacy, CEMEX Department, Iași, Romania
5.”Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine, Faculty of Veterinary Medicine, Iași, Romania -
ANTI α-GLUCOSIDASE, ANTITUMOUR, ANTIOXIDATIVE, ANTIMICROBIAL ACTIVITY, NUTRITIVE AND HEALTH PROTECTIVE POTENTIAL OF SOME SEAWEEDS FROM THE ADRIATIC COAST OF MONTENEGRO
SANJA MILOVIĆ 1, TATJANA KUNDAKOVIĆ 1, VESNA MAČIĆ 2, JELENA ANTIĆ STANKOVIĆ 1, NAĐA GROZDANIĆ 3, IVANA ĐURIČIĆ 1, IVAN STANKOVIĆ 1, TATJANA STANOJKOVIĆ 3*
1.Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia
2.Institute of Marine Biology, P.O. Box 69, 85330 Kotor, Montenegro
3.Institute of Oncology and Radiology of Serbia, Pasterova 14, 11000 Belgrade, Serbia -
BIOAVAILABILITY OF VALPROATE SUPPOSITORIES FORMULATED FOR PAEDIATRIC USE
NICOLETA TODORAN 1, ADRIANA CIURBA 1*, SZENDE VANCEA 2, CAMIL-EUGEN VARI 3, MARIA-TITICA DOGARU 3, ALEXANDRINA TĂUREAN 4, DANIELA-LUCIA MUNTEAN 5, ROBERT-ALEXANDRU VLAD 1, FELICIA GLIGOR 6
1.University of Medicine and Pharmacy of Tîrgu Mureş, Faculty of Pharmacy, Department of Pharmaceutical Technology, 38 Gh. Marinescu Street, 540139, Târgu Mureș, Romania
2.University of Medicine and Pharmacy of Tîrgu Mureş, Faculty of Pharmacy, Department of Physical Chemistry, 38 Gh. Marinescu Street, 540139, Târgu Mureș, Romania
3.University of Medicine and Pharmacy of Tîrgu Mureş, Faculty of Pharmacy, Department of Pharmacology and Clinical Pharmacy, 38 Gh. Marinescu Street, 540139, Târgu Mureș, Romania
4.Pharmacy no.3, Emergency Clinical County Hospital of Târgu Mureș, 50 Gh. Marinescu Street, 540136, Târgu Mureș, Romania
5.University of Medicine and Pharmacy of Tîrgu Mureş, Faculty of Pharmacy, Department of Analytical Chemistry and Analysis of Medicine, 38 Gh. Marinescu Street, 540139, Târgu Mureș, Romania
6.“Lucian Blaga” University, Faculty of Medicine, Department of Biochemistry, 10 Victoriei Blvd., 550024, Sibiu, Romania -
VARIATION OF POLYPHENOLS AND IRON CONCENTRATION IN MENTHA X PIPERITA L. BY DEVELOPMENT STAGE AND SOIL TYPE
ROBERT ANCUCEANU 1, MARILENA VIORICA HOVANEȚ 1*, ADRIANA IULIANA ANGHEL 1, MIHAELA DINU 1, ALINA DUNE 2, MARIA CIOLEA 2, OCTAVIAN TUDOREL OLARU 1, CARMEN POPESCU 2,3
1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Bucharest, Romania
2.S.C. HOFIGAL Export Import S.A., Bucharest, Romania
3.“Vasile Goldiş” Western University, Faculty of Pharmacy, Arad, Romania -
HPLC-UV DETERMINATION OF INDAPAMIDE IN THE PRESENCE OF ITS MAIN SYNTHESIS AND DEGRADATION IMPURITIES. METHOD VALIDATION
SIMONA CODRUȚA HEGHEȘ 1#, LUCIA MARIA RUS 1#, LUCA-LIVIU RUS 2*, MARIUS TRAIAN BOJIȚĂ 1, CRISTINA ADELA IUGA 1,3
1.Department of Drug Analysis, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 6 Pasteur Street, Cluj-Napoca, Romania
2.Preclinical Department, Faculty of Medicine, “Lucian Blaga” University, 2A Lucian Blaga Street, Sibiu, Romania
3.Proteomic and Metabolomic Department, MedFUTURE - Research Centre for Advanced Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy, 4-6 Louis Pasteur Street, 23 Marinescu Street, Cluj-Napoca, Romania -
OPTIMIZED AND VALIDATED SPECTROPHOTOMETRIC DETERMINATION OF BUTAMIRATE CITRATE IN BULK AND DOSAGE FORMS USING ION-PAIR FORMATION WITH METHYL ORANGE AND BROMOTHYMOL BLUE
DUYGU TAŞKIN 1*, GIZEM ERENSOY 2, SIDIKA SUNGUR 1
1.Istanbul Yeni Yuzyil University, Faculty of Pharmacy, Department of Analytical Chemistry, Istanbul, Turkey
2.Istanbul Yeni Yuzyil University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Istanbul, Turkey -
LIGUSTRUM VULGARE HYDROALCOHOLIC EXTRACT INDUCES APOPTOTIC CELL DEATH IN HUMAN PRIMARY BRAIN TUMOUR CELLS
LIGIA GABRIELA TĂTĂRANU 1#, ADA MARIA GEORGESCU 2#, SANDRA ALICE BUTEICĂ 3#, ISABELA SILOȘI 2#, GEORGE DAN MOGOȘANU 4#, ȘTEFANA OANA PURCARU 2#, OANA ALEXANDRU 2#, OLIVIAN PUIU STOVICEK 5#, CORINA BRÎNDUȘA 2#, MONICA DOȘA 6#, CITTO IULIAN TAISESCU 7#, ANICA DRICU 2#*
1.Department of Neurosurgery, “Bagdasar-Arseni” Emergency Clinical Hospital, 12 Berceni Street, 041915, Bucharest, Romania
2.Department of Biochemistry, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rareș Street, 200349, Craiova, Romania
3.Department of Drug Control, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2 Petru Rareș Street, 200349, Craiova, Romania
4.Department of Pharmacognosy-Phytotherapy, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2 Petru Rareș Street, 200349, Craiova, Romania
5.Department of Pharmacology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rareș Street, 200349, Craiova, Romania
6.Department of Pharmacology, Faculty of Medicine, “Ovidius” University of Constanța, 1 Aleea Universității Street, Constanța, Romania
7.Department of Physiology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rareș Street, 200349, Craiova, Romania -
NEW APPROACHES REGARDING THE USE OF ACTOVEGIN® IN SUBACUTE/POSTACUTE/SUBCHRONIC TRAUMATIC BRAIN INJURY PATIENTS
GELU ONOSE 1,2*, DOROTEEA TEOIBAȘ-ȘERBAN 1, CRISTINA POPESCU 1,2, IOANA ANDONE 1, ELENA BRUMĂ 1, ANCA MIHĂESCU1 , MONICA HARAS 1,2, ANA MARIA BUMBEA 3,4, AURELIAN ANGHELESCU 1,2, TIBERIU SPIRCU 2, CRISTINEL BADIU 1,2, CRISTINA DAIA 1,2
1.“Bagdasar Arseni” Teaching Emergency Hospital, Bucharest, Romania
2.“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
3.Teaching Neuropsychiatry Hospital, Craiova, Romania
4.University of Medicine and Pharmacy, Craiova, Romania -
SYNERGIC BENEFITS OF ARONIA MELANOCARPA ANTHOCYANIN – RICH EXTRACTS AND ANTIBIOTICS USED FOR URINARY TRACT INFECTIONS
REMO DORNEANU 1, OANA CIOANCĂ 1*, OANA CHIFIRIUC 2, ELENA ALBU 1, CRISTINA TUCHILUŞ 1, CORNELIA MIRCEA 1, IVAN SALAMON 3, MONICA HĂNCIANU 1
1.“Gr. T. Popa” University of Medicine and Pharmacy, 16 Universității Street, Iași, Romania
2.Research Institute of the University of Bucharest, Bucharest, Romania
3.University of Presov, 15 17th November Street, Presov, Slovak Republic -
THE CORRELATION BETWEEN DIFFERENT DOSES OF GLUTAMINE ON THE APOPTOSIS OF LYMPHOCYTES IN A MURINE MODEL OF SEPSIS
RAN LIU 1#, XIANKE LI 1#, KAI YU 1*, YONG WANG 2
1.Department of Anaesthesiology, the First People's Hospital of Jining, Jining, Shandong, 272011, China
2.Anaesthesia Department of the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China -
DETERMINATION OF IBUPROFEN BASED ON SCREEN-PRINTED ELECTRODES MODIFIED WITH CARBON NANOFIBERS
IRINA MIRELA APETREI 1, ADRIANA AURORA BEJINARU 2, MONICA BOEV 1, CONSTANTIN APETREI 3*, OLIMPIA DUMITRIU BUZIA 1
1.Department of Pharmaceutical Sciences, Medical and Pharmaceutical Research Centre, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University of Galați, Romania
2.Department of Dental Medicine, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University of Galați, Romania
3.Department of Chemistry, Physics and Environment, “Dunărea de Jos” University of Galați, Romania -
MONOSACCHARIDES COMPOSITION AND CYTOSTATIC ACTIVITY OF POLYSACCHARIDE FRACTION OF PHEMERANTHUS CONFERTIFLORUS L.
FLORENTINA GATEA 1, EUGENIA DUMITRA TEODOR 1*, ANA MARIA SECIU 2, LETIȚIA ELENA RADU 3
1.National Institute for Biological Sciences, Centre of Bioanalysis, 296 Splaiul Independenței Street, 060031, Bucharest, Romania
2.National Institute for Biological Sciences, Department of Cell and Molecular Biology, 296 Splaiul Independenței Street, 060031, Bucharest, Romania
3.Fundeni Clinic Institute, 258 Fundeni Road, 022328, Bucharest, Romania -
CHEMICAL COMPOSITION AND FUNCTIONAL PROPERTIES OF ESSENTIAL OILS FROM NEPETA SCHIRAZIANA BOISS.
JAVAD SHARIFI-RAD 1, SEYED ABDULMAJID AYATOLLAHI 1,2, ELENA M. VARONI 3, BAHARE SALEHI 4, FARZAD KOBARFARD 1,5, MEHDI SHARIFI-RAD 6, MARCELLO IRITI 7*, MARZIEH SHARIFI-RAD 1
1.Phytochemistry Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2.Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences Tehran, Iran
3.Department of Biomedical, Surgical and Dental Sciences, Milan State University, Italy
4.Young Researchers and Elites Club, North Tehran Branch, Islamic Azad University, Tehran, Iran
5.Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Iran
6.Department of Medical Parasitology, Zabol University of Medical Sciences, Zabol 61663-335, Iran
7.Department of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, Milan 20133, Italy -
ANTIBACTERIAL EFFICIENCY OF FIVE PROPOLIS EXTRACTS ON PLANKTONIC AND ADHERENT MICROBIAL STRAINS
ABBAS HAZEM 1, CARMEN VIOLETA POPESCU 3,4*, IULIANA CRIȘAN 3, MARCELA POPA 2, MARIANA CARMEN CHIFIRIUC 2, GRAȚIELA GRADIȘTEANU PIRCALABIORU 2, DUMITRU LUPULIASA 1
1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Bucharest, Romania
2.Research Institute of the University of Bucharest, ICUB, Bucharest, Romania
3.S.C. HOFIGAL Export Import S.A., Bucharest, Romania
4.“Vasile Goldiş” Western University, Faculty of Pharmacy, Arad, Romania