Romanian Society of Pharmaceutical Sciences
 

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NEW SYNTHESIS OF DIPHENYLSULPHONAMIDES COMPOUNDS WITH PHARMACOLOGICAL PROPERTIES. NOTE II

IOANA DANA ROTARU (ENACHE) 1, DIANA CAMELIA NUŢĂ 1*, ILEANA CORNELIA CHIRIŢĂ 1, ALEXANDRU-VASILE MISSIR 1, CARMELLINA DANIELA BĂDICEANU 1, LAURENŢIU MORUŞCIAG 1, MIRON TEODOR CĂPROIU 2, CARMEN LIMBAN 1

1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Bucharest, Romania, 6 Traian Vuia St., 020956, Bucharest, Romania
2.“C. D. Neniţescu” The Organic Chemistry Centre of Romanian Academy, 202B Splaiul Independenţei St., Bucharest, Romania

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A series of sulfonylurea derivatives was synthesized, using as a starting point the corresponding azide. This was subjected to Curtis degradation, after which it was condensed with primary aromatic amines. The structures of the new derivatives were confirmed by elemental analysis and spectrometry in IR and NMR.