Romanian Society of Pharmaceutical Sciences
 

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MONOSACCHARIDES COMPOSITION AND CYTOSTATIC ACTIVITY OF POLYSACCHARIDE FRACTION OF PHEMERANTHUS CONFERTIFLORUS L.

FLORENTINA GATEA 1, EUGENIA DUMITRA TEODOR 1*, ANA MARIA SECIU 2, LETIȚIA ELENA RADU 3

1.National Institute for Biological Sciences, Centre of Bioanalysis, 296 Splaiul Independenței Street, 060031, Bucharest, Romania
2.National Institute for Biological Sciences, Department of Cell and Molecular Biology, 296 Splaiul Independenței Street, 060031, Bucharest, Romania
3.Fundeni Clinic Institute, 258 Fundeni Road, 022328, Bucharest, Romania

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Polysaccharides display several biological activities, such as antitumour, anti-oxidation, hypoglycaemic, antiviral and immunity enhancing properties. The polysaccharide fraction from Phemeranthus confertiflorus was extracted, hydrolysed and 8 monosaccharides were analysed and quantified by capillary electrophoresis. The polysaccharide fraction was further assessed for cytotoxicity on normal and tumour cell lines. The results obtained can promote Phemeranthus as an eligible plant with potential for human health, because of high monosaccharides content (predominant rhamnose) and promising cytostatic effect of polysaccharide fraction.