Farmacia Journal 3/2016

Volume 64 | Number 3 | Year 2016

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1. GENETICS OF PSORIASIS SUSCEPTIBILITY AND TREATMENT RESPONSE

   VLAD MIHAI VOICULESCU^1,2, LILIANA GABRIELA POPA^2*, ROXANA SILVIA BUMBACEA^1,2, CORNELIA NITIPIR², CALIN GIURCANEANU^1,2

   1.”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania - Oncologic dermatology and allergology Clinic
   2.”Elias” University Emergency Hospital, Bucharest, Romania - Dermatology Department

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2. BRYONIA ALBA L. AND ECBALLIUM ELATERIUM (L.) A. RICH. – TWO RELATED SPECIES OF THE CUCURBITACEAE FAMILY WITH IMPORTANT PHARMACEUTICAL POTENTIAL

   IRINA IELCIU¹, MICHEL FRÉDÉRICH^2*, MONIQUE TITS², LUC ANGENOT², RAMONA PĂLTINEAN¹, EWA CIECKIEWICZ², GIANINA CRIŞAN¹, LAURIAN VLASE³

   1.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Botany, 23 Gheorghe Marinescu Street, Cluj-Napoca, Romania
   2.Center of Interdisciplinary Research on Medicines, Laboratory of Pharmacognosy, University of Liège, 15 Avenue de Hippocrate, B36, Tour 4 (+3), 4000 Liège, Belgium
   3.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, 12 Ion Creangă Street, Cluj-Napoca, Romania

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3. PELARGONIUM SP.: CHARACTERIZATION OF THE POLYPHENOLS AND THEIR BIOLOGICAL POTENTIAL

   CRISTINA IANCU¹, OANA CIOANCĂ², CORNELIA MIRCEA^1*, MADALINA MOCANU³, MONICA HĂNCIANU²

   “Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy, 16 Universităţii Street, 700115, Iași, Romania
   1.Department of Pharmaceutical Biochemistry and Clinical Laboratory
   2.Department of Pharmacognosy
   3.Department of Physiopathology

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4. AB INITIO AND DENSITY FUNCTIONAL THEORY STUDY ON IONIZATION OF BETAHISTINE AND CIMETIDINE NANO DRUG IN AQUEOUS SOLUTION

   FARHOUSH KIANI^*, BAHAREH KHANLARZADEH, HASAN TAHERMANSOURI

   Department of Chemistry, Faculty of Science, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran

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5. INFLUENCE OF RESIDUAL DIURESIS ON CARDIAC BIOMARKER NTproBNP IN CHRONIC HEMODIALYSIS PATIENTS

   ANA-MARIA NECHITA^1#, SILVIU PIȚURU^2#, DANIELA RĂDULESCU^1,3# ILEANA PERIDE^1,3#, LUCIAN NEGREANU^4,5#, ANDREI NICULAE^1#, DUMITRU FERECHIDE^6#, IONEL ALEXANDRU CHECHERIȚĂ^1,3#*, RUXANDRA DIANA SINESCU^7,8#

   1.Department of Nephrology and Dialysis, “St. John” Emergency Clinical Hospital, 13th Vitan-Bârzești Road, 042122, Bucharest, Romania
   2.“Carol Davila” University of Medicine and Pharmacy Bucharest, 37th Dionisie Lupu Street, 020022, Bucharest, Romania
   3.Clinical Department No. 3, “Carol Davila” University of Medicine and Pharmacy Bucharest, 37th Dionisie Lupu Street, 020022, Bucharest, Romania
   4.Department of Internal Medicine II – Gastroenterology, Emergency University Bucharest, 169th Splaiul Independentei, 050098, Bucharest, Romania
   5.Clinical Department No. 5, “Carol Davila” University of Medicine and Pharmacy Bucharest, 37th Dionisie Lupu Street, 020022, Bucharest, Romania
   6.Department of Physiology I, Clinical Department No. 2, “Carol Davila” University of Medicine and Pharmacy Bucharest, 37th Dionisie Lupu Street, 020022, Bucharest, Romania
   7.Department of Plastic Surgery and Reconstructive Microsurgery, “Elias” Emergency University Hospital Bucharest, 17th Mărăști Boulevard, 011461, Romania
   8.Clinical Department No. 11, “Carol Davila” University of Medicine and Pharmacy Bucharest, 37th Dionisie Lupu Street, 020022, Bucharest, Romania

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6. LONG TERM EFFECTS OF OLANZAPINE CUMULATIVE DOSES ON FAT TISSUE. AN EXPERIMENTAL MODEL IN RATS

   GEORGE ECHIM¹, CĂTĂLINA GABRIELA PISOSCHI^2*, CAMIL EUGEN VARI^3*, MELINDA KOLCSÀR³, BIANCA EUGENIA ŐSZ³, ZSOLT GÁLL³, CĂLIN CHIBELEAN⁴, ANCA BERBECARU-IOVAN⁵, MARIA T. DOGARU³

   1.Doctoral School, University of Medicine and Pharmacy Tîrgu Mureș, 38 Gh. Marinescu Street, RO-540139, Romania
   2.Department of Biochemistry, University of Medicine and Pharmacy Craiova, 2-4 Petru Rares Street, RO-200349, Romania
   3.Department of Pharmacology and Clinical Pharmacy, University of Medicine and Pharmacy Tîrgu Mureș, 38 Gh. Marinescu Street, RO-540139, Romania
   4.Department of Urology, University of Medicine and Pharmacy Tîrgu Mureș, 38 Gh. Marinescu Street, RO-540139, Romania
   5.Department of Pharmacology, University of Medicine and Pharmacy Craiova, 2-4 Petru Rares Street, RO-200349, Romania

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7. ANTI-ANXIETY EFFECT OF ARONIA MELANOCARPA FRUIT JUICE ADMINISTERED SUBCHRONICALLY TO RATS

   STEFKA VALCHEVA-KUZMANOVA^1*, MIROSLAV EFTIMOV¹, IREN BELCHEVA², STILIANA BELCHEVA³, ROMAN TASHEV^2,4

   1.Medical University “Prof. Dr. Paraskev Stoyanov”, Faculty of Medicine, Department of Preclinical and Clinical Pharmacology, 9002 Varna, Bulgaria
   2.Bulgarian Academy of Sciences, Institute of Neurobiology, Department of Behavioural Neurobiology, 1113 Sofia, Bulgaria
   3.Sofia University “St. Kl. Ohridski“, Faculty of Pre-School and Primary School Education, 1504 Sofia, Bulgaria
   4.Department of Pathophysiology, Medical University, Sofia, Bulgaria

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8. COMPARATIVE HISTO-ANATOMICAL RESEARCHES ON THE VEGETATIVE ORGANS AND ASSESSMENT OF ANTIOXIDANT CAPACITY OF TWO SPECIES FROM EQUISETUM GENUS

   ANNAMARIA PALLAG, BIANCA PAȘCA, TÜNDE JURCA, RAMONA SUCIU^*, SEBASTIAN NEMETH, LAURA VICAȘ

   University of Oradea, Faculty of Medicine and Pharmacy, Oradea, Romania

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9. IN VIVO AND IN VITRO CHARACTERIZATION OF A VACCINE RABIES STRAIN ISOLATED FROM FIELD

   VLAD VUTA^1,2*, GHEORGHE BARBOI^1,3, RAZVAN MOTIU¹, LENUTA ZAMFIR¹, FLORICA BARBUCEANU^1,2, CONSTANTIN VLAGIOIU²

   1.Institute for Diagnosis and Animal Health, 63 Dr. Staicovici Street, 050557, Bucharest, Romania
   2.Univerity of Agronomic Sciences and Veterinary Medicine-Faculty of Veterinary Medicine, 105 Splaiul Independentei, Bucharest, Romania
   3.“Spiru Haret” University, Faculty of Veterinary Medicine, 256 Basarabia Boulevard, Bucharest, Romania

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10. THE INFLUENCE OF PERINDOPRIL ON PTX3 PLASMA LEVELS IN HYPERTENSIVE PATIENTS WITH ENDOTHELIAL DYSFUNCTION

    VALENTINA BUDA ^1#*, MINODORA ANDOR ^2#, CARMEN CRISTESCU¹, MIRELA VOICU¹, LIANA SUCIU¹, CALIN MUNTEAN³, OCTAVIAN CRETU⁴, DANA EMILIA BÂIBÂȚĂ⁵, CRISTINA MONICA GHEORGHIU⁶, MIRELA CLEOPATRA TOMESCU²

    1.“Victor Babes" University of Medicine and Pharmacy Timișoara, Faculty of Pharmacy, Department of Pharmacology and Clinical Pharmacy, 2 Eftimie Murgu Street, 300041, Timișoara, Romania
    2.”Victor Babes" University of Medicine and Pharmacy Timișoara, Faculty of Medicine, Department of Medical Semiotics, 2 Eftimie Murgu Street, 300041, Timișoara, Romania
    3.”Victor Babes" University of Medicine and Pharmacy Timișoara, Faculty of Medicine, Department of Biostatistics and Medical Informatics, 2 Eftimie Murgu Street, 300041, Timișoara, Romania
    4.“Victor Babes" University of Medicine and Pharmacy Timișoara, Faculty of Medicine, Department of Medical Chirurgical Semiotics, 2 Eftimie Murgu Street, 300041, Timișoara, Romania
    5.“Victor Babes" University of Medicine and Pharmacy Timișoara, Faculty of Medicine, Department of Cardiology VI, 2 Eftimie Murgu Street, 300041, Timișoara, Romania
    6.Bioclinica Laboratory SA, 53 Cetatii Boulevard, 300654, Timișoara, Romania

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11. THIAZOLYL-OXADIAZOLE DERIVATIVES TARGETING LANOSTEROL 14α-DEMETHYLASE AS POTENTIAL ANTIFUNGAL AGENTS: DESIGN, SYNTHESIS AND MOLECULAR DOCKING STUDIES

    CRISTINA IOANA STOICA^1*, GABRIEL MARC¹, ADRIAN PÎRNĂU², LAURIAN VLASE¹, CĂTĂLIN ARANICIU¹, SMARANDA ONIGA¹, MARIANA PALAGE¹, OVIDIU ONIGA¹

    1.”Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, 12 Ion Creangă Str., RO-400010, Cluj-Napoca, Romania
    2.National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath Str., RO-400293, Cluj-Napoca, Romania

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12. SIMULTANEOUS DETERMINATION OF AMLODIPINE AND ATORVASTATIN BY CAPILLARY ELECTROPHORESIS FROM FIXED PHARMACEUTICAL FORMULATIONS

    ELEONORA MIRCIA¹, TEODORA BALACI^2*, GABRIEL HANCU³, VALENTIN ION⁴, ANCA CÂRJE⁴

    1.Department of Organic Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Tîrgu Mureş, Romania
    2.Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania
    3.Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Tîrgu Mureş, Romania
    4.Department of Drug Analysis and Analytical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Tîrgu Mureş, Romania

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13. PRELIMINARY ASSESSMENT OF THE ANTIOXIDANT, ANTIFUNGAL AND GERMINATION INHIBITORY POTENTIAL OF HERACLEUM SPHONDYLIUM L. (APIACEAE)

    RADU CLAUDIU FIERASCU¹, IOANA MARCELA PADURE², SORIN MARIUS AVRAMESCU³, CAMELIA UNGUREANU⁴, RALUCA IOANA BUNGHEZ¹, ALINA ORTAN⁵, CRISTINA DINU-PIRVU⁶, IRINA FIERASCU^1*, LILIANA CRISTINA SOARE⁷

    1.Nanomedicine Research Group, The National Institute for Research & Development in Chemistry and Petrochemistry, ICECHIM, Bucharest, Romania
    2.Faculty of Horticulture, University of Agronomic Science and Veterinary Medicine, Bucharest, Romania
    3.Research Center for Environmental Protection and Waste Management, University of Bucharest, Romania
    4.Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, Romania
    5.Faculty of Land Reclamation and Environmental Engineering, University of Agronomic Science and Veterinary Medicine, Bucharest, Romania
    6.Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania
    7.Department of Natural Sciences, University of Pitesti, Pitesti, Romania

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14. PHYTOCHEMICAL ANALYSIS OF FUMARIA OFFICINALIS L. (FUMARIACEAE)

    RAMONA PĂLTINEAN¹, ANCA TOIU^2*, JEAN NOËL WAUTERS³, MICHEL FRÉDÉRICH³, MONIQUE TITS³, LUC ANGENOT³, MIRCEA TĂMA޹, GIANINA CRIŞAN¹

    1.Department of Pharmaceutical Botany, Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 12 Ion Creanga Street, 400010 Cluj-Napoca, Romania
    2.Department of Pharmacognosy, Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 12 Ion Creanga Street, 400010 Cluj-Napoca, Romania
    3.Laboratory of Pharmacognosy, Center for Interdisciplinary Research on Medicines (CIRM), Faculty of Medicine, University of Liège, 1, Avenue de l' Hôpital, B-4000- Liege, Belgium

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15. COLLAGEN-SERICIN-NANO-HYDROXYAPATITE COMPOSITES FOR BONE TISSUE ENGINEERING

    MADALINA GEORGIANA ALBU¹, ADRIANA LUNGU², EUGENIU VASILE², HORIA IOVU^2*

    1.INCDTP-Division Leather and Footwear Research Institute, Bucharest, Romania
    2.Advanced Polymer Materials Group, Department of Bioresources and Polymer Science, University Politehnica of Bucharest, Bucharest, Romania

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16. THE EFFECTS OF SOY ISOFLAVONES AND HORMONAL REPLACING THERAPY ON THE INCIDENCE AND EVOLUTION OF POSTMENOPAUSAL FEMALE URINARY INCONTINENCE

    ADRIAN BUMBU¹, PAŞCA BIANCA², DELIA MIRELA TIT^2*, SIMONA BUNGAU², GHEORGHE BUMBU¹

    1.University of Oradea, Faculty of Medicine and Pharmacy, Surgical Disciplines Department, 10 Decembrie 1 St., Oradea, Romania
    2.University of Oradea, Faculty of Medicine and Pharmacy, Pharmacy Department, 29 N. Jiga St., Oradea, Romania

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17. VITAMIN D LEVELS ARE ASSOCIATED WITH SYSTEMIC LUPUS ERYTHEMATOSUS DISEASE ACTIVITY

    VIOLETA BOJINCĂ^1,2, CLAUDIU C. POPESCU^2,3*, IOANA CRISTINA SAULESCU^1,2, DANIELA OPRIS^1,2, ANDREEA BORANGIU^1,2, LAURA GROSEANU^1,2, ANDRA BALANESCU^1,2, RUXANDRA IONESCU^1,2, MIHAI BOJINCA^2,4

    1.“Sfanta Maria” Clinical Hospital, 37-39th Ion Mihalache Boulevard, Bucharest, Romania
    2.“Carol Davila” University of Medicine and Pharmacy, 37th Dionisie Lupu Street, Bucharest, Romania
    3.“Ion Stoia” Clinical Center for Rheumatic Diseases, 5th Thomas Masaryk Street, Bucharest, Romania
    4.“Dr. Ion Cantacuzino” Clinical Hospital, 5-7 Ion Movila Street, Bucharest, Romania

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18. CELLULAR IMPEDANCE MEASUREMENT – NOVEL METHOD FOR IN VITRO INVESTIGATION OF DRUG EFFICACY

    MIRCEA TAMPA¹, CLARA MATEI¹, CONSTANTIN CARUNTU², TEODOR POTECA^3*, DANA MIHAILA³, CATALIN PAUNESCU⁴, GABRIEL PITIGOI⁴, SIMONA-ROXANA GEORGESCU¹, CAROLINA CONSTANTIN⁵, MONICA NEAGU⁵

    1.Dermatology Department, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Boulevard, Bucharest, 050474, Romania
    2.Department of Physiology, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Boulevard, Bucharest, 050474, Romania
    3.Colentina Hospital, General Surgery Department, 19-21 Stefan Cel Mare, Bucharest, Romania
    4.Medical Recovery Department, “Carol Davila” University of Medicine and Pharmacy, 8 Eroii Sanitari Boulevard, Bucharest, 050474, Romania
    5."Victor Babes" National Institute of Pathology, Immunobiology Laboratory, 99-101 Splaiul Independentei, Bucharest, 050096, Romania

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19. VALIDATION AND CHARACTERIZATION OF A HEART FAILURE ANIMAL MODEL

    CRISTINA POP¹, CRISTIAN BERCE^*2, STELIANA GHIBU¹, ANCA POP³, BELA KISS³, ALEXANDRA IRIMIE⁴, ȘTEFAN POPA⁵, GABRIEL CISMARU⁶, FELICIA LOGHIN³, CRISTINA MOGOȘAN¹

    1.Department of Pharmacology, Physiology and Pathophysiology, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
    2.Experimental Medicine and Practical Skills Center, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
    3.Department of Toxicology, Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
    4.Department of Pathology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania
    5.Department of Internal Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
    6.Department of Cardiology, Rehabilitation Hospital, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

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20. EVALUATION OF THE EFFICACY AND SAFETY OF INTRAVITREAL BEVACIZUMAB FOR MACULAR EDEMA RELATED TO RETINAL VEIN OCCLUSION

    CALIN PETRU TATARU^1,2, RALUCA IANCU^1,3*, ANCA DOGAROIU², CAMELIA DIACONU⁴, CATALINA CORBU^1,2

    1.UMF “Carol Davila”, Ophthalmology Department, 8 Eroilor Sanitari, 050474, Bucharest, Romania
    2.Emergency Eye Hospital, 1 Al. Lahovary Square, Bucharest, Romania
    3.University Emergency Hospital Bucharest, 169 Splaiul Independentei, 050098, Bucharest, Romania
    4.Internal Medicine Clinic, Clinical Emergency Hospital of Bucharest, 8 Calea Floreasca, 014461, Bucharest, Romania

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21. FORMULATION OPTIMIZATION OF PRAVASTATIN LOADED LONG-CIRCULATING LIPOSOMES USING A DESIGN OF EXPERIMENTS

    BIANCA SYLVESTER, ALINA PORFIRE^*, DANA-MARIA MUNTEAN, LAURIAN VLASE, IOAN TOMUŢĂ

    Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, 400012, Romania

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22. INFLUENCE OF PROCESS PARAMETERS ON COMPRESSIBILITY, SOLUBILITY AND RELEASE CHARACTERISTICS OF MELT SONOCRYSTALLIZED FENOFIBRATE

    SACHINKUMAR PATIL^*, SHITALKUMAR PATIL, GEETA KAVATHEKAR

    Department of Pharmaceutics Ashokrao Mane College of Pharmacy, Peth-Vadagoan, Maharashtra, India-416112

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23. PERTINENCE OF VITAMIN D SUPPLEMENTATION IN THE ADULT ROMANIAN POPULATION

    CORINA-AURELIA ZUGRAVU^1*, FLORIN SOPTICA², MONICA TARCEA³, ALEXANDRA CUCU¹

    1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Nursing and Midwifery, 8 Eroii Sanitari, Bucharest, Romania
    2.“Dunarea de Jos” University, Faculty of Food Science and Engineering, 47 Domneasca, Galați, Romania
    3.University of Medicine and Pharmacy, Faculty of Nutrition, 38 Gheorghe Marinescu, Târgu Mureș, Romania

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24. PATIENT CHOICE OF PHARMACY AND SATISFACTION WITH PHARMACEUTICAL CARE – SLOVAK REGIONAL COMPARISON

    DANIELA MINARIKOVA^*, IVONA MALOVECKA, VILIAM FOLTAN

    Department of Organisation and Management in Pharmacy, Comenius University, Faculty of Pharmacy, Bratislava, Slovak Republic

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25. ISSUES ABOUT PROMOTING DRUGS IN ROMANIA. OPINIONS OF THE PHARMACEUTICAL REPRESENTATIVES

    LASZLO-ZOLTAN SZTANKOVSZKY¹, MAGDALENA IORGA^1*, CAMELIA SOPONARU², IOAN ANTOFIE³

    1.”Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, Department of Preventive Medicine and Interdisciplinarity, Iasi, Romania
    2.”Al. I. Cuza” University, Faculty of Psychology and Educational Sciences, Iasi, Romania
    3.”CFR” Clinical Hospital Cluj-Napoca, Cluj, Romania

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