Farmacia Journal 2/2019
Volume 67 | Number 2 | Year 2019
Download this issue’s covers and announcements.
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THE CONNECTION BETWEEN DIFFERENT NEUROTRANSMITTERS INVOLVED IN COGNITIVE PROCESSES
CLAUDIA HANDRA 1, OANA ANDREIA COMAN 2, LAURENȚIU COMAN 3, TUDOR ENACHE 4, SMARANDA STOLERU 2, ADELINA-MIHAELA SORESCU 2, ISABEL GHIȚĂ 2*, ION FULGA 2
1.Department of Work Medicine, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
2.Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
3.Department of Physiology, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
4.Department of Physiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania -
SUPERCRITICAL FLUID TECHNOLOGY AND SUPERCRITICAL FLUID CHROMATOGRAPHY FOR APPLICATION IN GINSENG EXTRACTS
MAYYA PETROVNA RAZGONOVA 1, ALEXANDER MIKHAILOVICH ZAKHARENKO 1, TATIANA KUZMINICHNA KALENIK 2, ALEXANDER EVGENYEVICH NOSYREV 3, ANTONIS K. STRATIDAKIS 4, YAROSLAV OLEGOVYCH MEZHUEV 5, TATYANA I. BURYKINA 6, ALINA CRENGUȚA NICOLAE 7, ANDREEA LETIȚIA ARSENE 7, ARISTIDIS MICHAEL TSATSAKIS 3,4,5, KIRILL SERGEYEVICH GOLOKHVAST 1,8*
1.Scientific Education Center in Nanotechnology, Far-Eastern Federal University, Vladivostok, Far East, Russian Federation
2.School of Biomedicine, Far-Eastern Federal University, 690950, Vladivostok, Far East, Russian Federation
3.Central Chemical Laboratory of Toxicology, I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation
4.Laboratory of Toxicology, School of Medicine, University of Crete, Heraklion 71003, Greece
5.Dmitry Mendeleev University of Chemical Technology of Russia, Miusskaya Square, 9, Moscow 125047, Russian Federation
6.Department of Analytical and Forensic Medical Toxicology, Sechenov University, Moscow 119991, Russian Federation
7.Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
8.Pacific Geographical Institute FEB RAS, 7 Radio street, Vladivostok, 690041, Russian Federation -
NEW DEVELOPMENTS IN THE TREATMENT OF ALCOHOL USE DISORDER
MARIA BONEA *, IOANA VALENTINA MICLUȚIA
“Iuliu Hațieganu” University of Medicine and Pharmacy, Department of Neuroscience, Psychiatry, 43 Victor Babeș Street, 400012, Cluj-Napoca, Romania
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KETOGENIC DIET TREATMENT FOR STATUS EPILEPTICUS
CARMEN SANDU ,2*, SANDA ADRIANA MAGUREANU 1, CATRINEL ILIESCU 1,2, CRISTINA POMERAN 1,2, DANA CRISTINA CRAIU 1,2
1.Pediatric Neurology II Discipline, Clinical Neurosciences Department, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2.Pediatric Neurology Clinic, "Prof. Dr. Alexandru Obregia" Clinical Hospital, 10, Berceni Avenue, 4th District, 041914, Bucharest, Romania -
POSSIBLE MOLECULAR MECHANISMS AND PATHWAYS INVOLVED IN BH3 MIMETIC ACTIVITY OF ALPHA-LIPOIC ACID ON HUMAN COLON CANCER CELL LINE
IVANA DAMNJANOVIC 1*, GORDANA KOCIC 2, STEVO NAJMAN 3, SANJA STOJANOVIC 3, KATARINA TOMOVIC 1, BUDIMIR ILIC 4, ANDREJ VELJKOVIC 2, SRDJAN PESIC 5, ANDRIJA SMELCEROVIC 1,4
1.Department of Pharmacy, Faculty of Medicine, University of Nis, Blvd. Dr Zorana Djindjica 81, 1800 Nis, Serbia
2.Department of Biochemistry, Faculty of Medicine, University of Nis, Blvd. Dr Zorana Djindjica 81, 18000 Nis, Serbia
3.Department for Cell and Tissue Engineering, Institute of Biology and Human Genetics, Faculty of Medicine, University of Nis, Blvd. Dr Zorana Djindjica 81, 18000 Nis, Serbia
4.Department of Chemistry, Faculty of Medicine, University of Nis, Blvd. Dr Zorana Djindjica 81, 18000 Nis, Serbia
5.Department of Pharmacology, Faculty of Medicine, University of Nis, Blvd. Dr Zorana Djindjica 81, 18000 Nis, Serbia -
IMMUNOCHEMICAL ASSAY OF CHLORAMPHENICOL IN HONEY
IONELA DANIELA MORARIU, LILIANA AVASILCĂI, MĂDĂLINA VIERIU, OANA CIOANCĂ *, MONICA HĂNCIANU
“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy, 16 Universităţii Street, 700115, Iaşi, Romania
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CHARACTERISATION OF AN IN VITRO AGED CELL CULTURE MODEL
MARKO BUNC 1, SARA M HANNING 2, JOSE M PRIETO 3, JULIJANA KRISTL 1, MINE ORLU 3*
1.University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia
2.University of Auckland, School of Pharmacy, Private Bag 92019, Auckland 1142, New Zealand
3.University College London, UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom -
IN-LINE FLUID BED GRANULATION MONITORING BY NIR SPECTROSCOPY. METHOD DEVELOPMENT AND VALIDATION
ALEXANDRU GAVAN *, BIANCA SYLVESTER, TIBOR CASIAN, IOAN TOMUȚĂ
“Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, 41 V. Babeș Street, 400012, Cluj-Napoca, Romania
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THE ANALGESIC EFFECT OF 1,3-THIAZOLIDIN-4-ONE DERIVATIVES AS POTENTIAL MODULATORS OF THE SEROTONINERGIC SYSTEM
IWONA PIĄTKOWSKA-CHMIEL 1*, ŁUKASZ POPIOŁEK 2, MONIKA GAWROŃSKA-GRZYWACZ 1, DOROTA NATORSKA-CHOMICKA 1, MAGDALENA IZDEBSKA 1, MARIOLA HERBET 1, JAROSŁAW DUDKA 1, EWA POLESZAK 3, MONIKA WUJEC 2
1.Department of Toxicology, Medical University of Lublin, 8b Jaczewski St., PL 20-090 Lublin, Poland
2.Department of Organic Chemistry, Medical University of Lublin, 4a Chodźki St., PL 20-093 Lublin, Poland
3.Department of Applied Pharmacy Faculty of Pharmacy, Medical University of Lublin, 1 Chodźki St., PL 20-093 Lublin, Poland -
EFFECT OF ULINASTATIN ON REGULATORY T CELLS AND T HELPER 17 CELLS IN PATIENTS WITH SEVERE SEPSIS
GUOHUI LI 1, JILIN MA 2, LONG CAI 3, ZHANLI SHI 4, JING SUN 4, JIAYING ZHANG 4, ZHIHUI LI 4, LEIMIN SUN 4, HONGJUAN ZHOU 3, KUN FANG 4, SU YU 2*
1.Department of Occupational Medicine, Hang Zhou Red Cross Hospital, Hangzhou, 310003, China
2.Department of Rheumatology, Immunology and Nephrology, Hang Zhou Red Cross Hospital, Hangzhou, 310003, China
3.Central Laboratory, Hang Zhou Red Cross Hospital, Hangzhou, 310003, China
4.Department of Intensive Care Unit, Hang Zhou Red Cross Hospital, Hangzhou, 310003, China -
INFLUENCE OF MAGNESIUM COMPOUNDS ON SODIUM, POTASSIUM AND CALCIUM LEVELS IN DIFFERENT MICE ORGANS
CORINA MOISA 1, OANA CADAR 2*, REKA BARABAS 3, LAURA GRATIELA VICAS 1, MARIA-ALEXANDRA HOAGHIA 2, ERIKA-ANDREA LEVEI 2, CLAUDIA JURCA 1, CRISTIAN BERCE 4
1.University of Oradea, Medicine and Pharmacy Faculty, Department of Pharmacy, 29 Nicolae Jiga Street, 410028, Oradea, Romania
2.INCDO-INOE 2000, Research Institute for Analytical Instrumentation, 67 Donath Street, 400293, Cluj-Napoca, Romania
3.Babeș-Bolyai University, Faculty of Chemistry and Chemical Engineering, 11 Arany Janos Street, 400028, Cluj-Napoca, Romania
4.“Iuliu Hațieganu” University of Medicine and Pharmacy, Centre for Experimental Medicine, Laboratory animal facility, 6 Louis Pasteur Street, 400349, Cluj-Napoca, Romania -
DEVELOPMENT AND EVALUATION OF NEBIVOLOL HYDROCHLORIDE NANOCRYSTALS IMPREGNATED BUCCAL FILM
BANDAR E AL-DHUBIAB 1*, ANROOP B NAIR 1, RACHNA KUMRIA 2, MAHESH ATTIMARAD 1, SREE HARSHA 1
1.Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Kingdom of Saudi Arabia
2.Swift School of Pharmacy, Village-Ghaggar Sarai, Rajpura, Patiala, Punjab, India -
DESIGNING NEW MOTHER TINCTURES FOR INCREASED ANTIOXIDANT EFFICIENCY ON INFLAMMATORY INTESTINAL DISEASES
SORINA NICOLETA VOICU 1, ANCA HERMENEAN 2,3, NELI-KINGA OLAH 4,5, LILIANA BADULESCU 6, MIRUNA SILVIA STAN 1*, ANCA DINISCHIOTU 1
1.Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, Romania
2.The Institute of Life Sciences, “Vasile Goldiș” Western University of Arad, Arad, Romania
3.Department of Histology, Faculty of Medicine, “Vasile Goldiș” Western, University of Arad, Arad
4.SC PlantExtrakt SRL, 407059 Rădaia, Cluj-Napoca, Romania
5.“Vasile Goldiș” Western University of Arad, Faculty of Pharmacy, 86 L. Rebreanu, 310414 Arad, Romania
6.Department of Bioengineering of Horticulture Systems, University of Agronomic Sciences and Veterinary Medicine, 59 Mărăști Boulevard, 011464 Bucharest, Romania -
THE BEHAVIORAL STUDY OF THE EFFECTS OF ATRISTAMINE ON THE SEROTONIN, DOPAMINE AND NOREPINEPHRINE NEUROTRANSMITTER SYSTEMS IN MICE
ILLYA PODOLSKY *, SERGIY SHTRYGOL′
National University of Pharmacy, Kharkiv, Ukraine
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THE EFFECTS OF NEW 1,3-THIAZOLIDINE-4-ONES WITH PYRRAZOLONE SCAFOLD ON MOTOR FUNCTION IN MICE
MARIA APOTROSOAEI 1, IOANA MIRELA VASINCU 1*, SANDRA MĂDĂLINA CONSTANTIN 1, ANDREEA-TEODORA IACOB 1, GEORGIANA-ROXANA TAUȘER 1, DAN LUPAȘCU 1, CĂTĂLINA-ELENA LUPUȘORU 2, LENUȚA PROFIRE 1
1.”Grigore. T. Popa” University of Medicine and Pharmacy Iași, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Universității Street, no. 16, 700115, Iași, Romania
2.”Grigore. T. Popa” University of Medicine and Pharmacy Iași, Faculty of Medicine, Department of Pharmacology, Clinical Pharmacology and Algesiology, Universității Street, no. 16, 700115, Iași, Romania -
PHENOLIC COMPOSITION, VOLATILE CONSTITUENTS AND ANTIOXIDANT POTENTIAL OF WILD EDIBLE FRUIT ELAEOCARPUS TECTORIUS (LOUR.) POIR. (ELAEOCARPACEAE)
ABHISHEK MUNDARAGI 1, DEVARAJAN THANGADURAI 1*, JEYABALAN SANGEETHA 2, SHIVANAND BHAT 3
1.Department of Botany, Karnatak University, Dharwad, Karnataka, 580003, India
2.Department of Environmental Science, Central University of Kerala, Kasaragod, Kerala 671316, India
3.Department of Botany, Government Arts and Science College, Karwar, Karnataka 581301, India -
RESULTS OF ALENDRONATE TREATMENT IN PATIENTS DIAGNOSED WITH ASEPTIC OSTEONECROSIS OF THE FEMORAL HEAD
KAMAL CONSTANTIN KAMAL 1#, DRAGOȘ OVIDIU ALEXANDRU 2*, OTILIA CONSTANTINA ROGOVEANU 3, DIANA KAMAL 4#, ALICE SANDRA BUTEICĂ 5#, TUDOR ADRIAN BĂLŞEANU 6, CAMELIA PĂNUȘ 7, DANIELA TEODORA MARIA 8#, MAGDALENA RODICA TRĂISTARU 3
1.Family Medicine Department, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rares St., 200349, Craiova, Romania
2.Department of Medical Informatics and Biostatistics, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rares St., 200349, Craiova, Romania
3.Physical and Rehabilitation Medicine Department, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rares St., 200349, Craiova, Romania
4.Physical and Rehabilitation Medicine Department, Medical Clinic Elga, University of Medicine and Pharmacy of Craiova, 2 Mihai Eminescu Str., 200131, Craiova, Romania
5.Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rares St., 200349, Craiova, Romania
6.Department of Physiology, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rares St., 200349, Craiova, Romania
7.Department of Diabetes, Nutrition and Metabolic Disease, Emergency Clinical County Hospital of Craiova, University of Medicine and Pharmacy of Craiova, 1Tabaci St., 200642, Craiova, Romania
8.Nephrology Department, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rares St., 200349, Craiova, Romania -
ANTIOXIDANT POTENTIAL OF SOME PLANTS USED IN FOLK MEDICINE IN ROMANIA
NÓRA PAPP 1*, NIKOLETT SALI 2,3, RITA CSEPREGI 2, MÓNIKA TÓTH 1, KINGA GYERGYÁK 1, TÜNDE DÉNES 1, SÁMUEL GERGELY BARTHA 1, ERZSÉBET VARGA 4, ANDREA KASZÁS 1, TAMÁS KŐSZEGI 2,3
1.Department of Pharmacognosy, Faculty of Pharmacy, University of Pécs, Rókus 2, H-7624, Pécs, Hungary
2.Department of Laboratory Medicine, Medical School, University of Pécs, Ifjúság 13, H-7624, Pécs, Hungary
3.János Szentágothai Research Center, Ifjúság 20, H-7624 Pécs, Hungary
4.Department of Pharmacognosy and Phytotherapy, University of Medicine and Pharmacy, 540139 Târgu Mureş, Romania -
HYDROXYSAFFLOR YELLOW A REVERSE CHEMOTHERAPY RESISTANCE VIA JNK AND P38 MAPK SIGNAL PATHWAY IN OVARIAN CANCER CELLS
CHENYU JIN 1, JIALE YING 2, WEIJI YANG 3, RUOJIA LIANG 4*
1.Department of Traditional Chinese Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China
2.The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, 310053, China
3.College of Life Science, Zhejiang Chinese Medical University, Hangzhou, 310053, China
4.Department of Gynaecology, The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, 310006, China -
PREVALENCE AND THE PATTERNS OF USE OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) AND PARACETAMOL AMONG THE GENERAL POPULATION
MARIA SUCIU 1#, LIANA SUCIU 1#, LAVINIA VLAIA 1*, MIRELA VOICU 1, VALENTINA BUDA 1, LIANA DRĂGAN 1, MINODORA ANDOR 2, VICENŢIU VLAIA 1, CARMEN CRISTESCU 1
1.”Victor Babeş” University of Medicine and Pharmacy, Faculty of Pharmacy, Eftimie Murgu Square no. 2, 300041, Timişoara, Romania
2.” Victor Babeş” University of Medicine and Pharmacy, Faculty of Medicine, Eftimie Murgu Square no. 2, 300041, Timişoara, Romania -
PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL ACTIVITY OF EXTRACTS OF LICHEN PHYSCIA SEMIPINNATA: AS A NEW SOURCE OF PHARMACOLOGICALLY ACTIVE COMPOUNDS
JOVICA TOMOVIĆ 1, MARIJANA KOSANIĆ 2, BRANISLAV RANKOVIĆ 2, PERICA VASILJEVIĆ 3, STEVO NAJMAN 4, NEDELJKO MANOJLOVIĆ 1*
1.University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Pharmacy, 34000 Kragujevac, Serbia
2.University of Kragujevac, Faculty of Science, Department of Biology, 34000 Kragujevac, Serbia
3.University of Niš, Serbia, Faculty of Science, 18000 Niš, Serbia
4.University of Niš, Serbia, Faculty of Medicine, 18000 Niš, Serbia -
EVALUATION OF ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF THE AQUEOUS METHANOLIC EXTRACT OF ASPRARAGUS RACEMOSUS IN EXPERIMENTAL MODELS
HASEEB AHSAN 1*, IHTISHAM HAIDER 2, MUHAMMAD NAVEED MUSHTAQ 3, IRFAN ANJUM 3
1.College of pharmacy, University of Sargodha, Sargodha, Pakistan
2.Nawaz Sharif medical college, University of Gujrat, Pakistan
3.Faculty of Pharmacy, Department of Pharmacology, The University of Lahore, Lahore, Pakistan -
CHANGES IN THE CYTOKINE LEVELS IN ADOLESCENTS WITH GINGIVITIS AFTER TREATMENT WITH PROPOLIS
STELA PEYCHEVA 1, ELISAVETA APOSTOLOVA 2*, ZHIVKO PEYCHEV 3, PETYA GARDJEVA 4, ANTON SLAVOV 5, MARIANNA MURDJEVA 4
1.Department of Paediatric Dental Medicine, Faculty of Dental Medicine, Medical University-Plovdiv, 15A Vassil Aprilov Blvd. 4002, Plovdiv, Bulgaria.
2.Department of Pharmacology and Drug Toxicology, Faculty of Pharmacy, Medical University-Plovdiv, 15A Vassil Aprilov Blvd. 4002, Plovdiv, Bulgaria.
3.Department of Medical Informatics, Biostatistics and e-learning, Faculty of Public Health, Medical University-Plovdiv, 15A Vassil Aprilov Blvd. 4002, Plovdiv, Bulgaria.
4.Department of Microbiology and Immunology, Faculty of Pharmacy, Medical University-Plovdiv, 15A Vassil Aprilov Blvd. 4002, Plovdiv, Bulgaria.
5.Department of Organic and Inorganic Chemistry, Faculty of Technology, University of Food Technologies–26 Maritsa Blvd., Plovdiv 4000, Bulgaria. -
DNA TARGETING AS A MOLECULAR MECHANISM UNDERLYING ENDOGENOUS INDOLES BIOLOGICAL EFFECTS
CRISTINA MANUELA DRĂGOI 1, ALINA CRENGUŢA NICOLAE 1*, ION-BOGDAN DUMITRESCU 2, DANIELA ELENA POPA 3, MIRELA RITIVOIU 4, ANDREEA LETIŢIA ARSENE 5
1.Department of Biochemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2.Department of Physics and Informatics, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
3.Department of Drug Control, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
4.Department of Paediatrics, Faculty of Medicine, “Alessandrescu-Rusescu” INSMC, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,
5.Department of Microbiology, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania -
INTERNSHIPS AND THE NEXT GENERATION OF PHARMACISTS IN ROMANIA
CĂTĂLINA LILIANA ANDREI 1, DRAGOȘ FLORIAN CIOLAN 2*, ANDREEA MIRICĂ 3, IULIA ELENA TOMA 3, DOINA DRĂGĂNESCU 4, FLAVIAN ȘTEFAN RĂDULESCU 2
1.“Carol Davila” University of Medicine and Pharmacy, Department of Cardiology and Thoracic Pathology, Bucharest, Romania
2.“Carol Davila” University of Medicine and Pharmacy, Center for Drug Sciences (CedS), Bucharest, Romania
3.Bucharest University of Economic Studies, Faculty of Economic Cybernetics, Statistics and Informatics, Statistics and Econometrics Department, Bucharest, Romania
4.“Carol Davila” University of Medicine and Pharmacy, Department of Pharmaceutical Physics and Informatics, Bucharest, Romania