Romanian Society of Pharmaceutical Sciences
 

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EVALUATION OF ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF THE AQUEOUS METHANOLIC EXTRACT OF ASPRARAGUS RACEMOSUS IN EXPERIMENTAL MODELS

HASEEB AHSAN 1*, IHTISHAM HAIDER 2, MUHAMMAD NAVEED MUSHTAQ 3, IRFAN ANJUM 3

1.College of pharmacy, University of Sargodha, Sargodha, Pakistan
2.Nawaz Sharif medical college, University of Gujrat, Pakistan
3.Faculty of Pharmacy, Department of Pharmacology, The University of Lahore, Lahore, Pakistan

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The aim of the present study was to evaluate the anti-inflammatory and analgesic activity of the aqueous methanolic extract of the root of Asparagus racemosus in Albino mice model. Oedema models were induced by injection of carrageenan and fresh egg albumin into right hind paw. Acetic acid and formalin were used to induce pain models. The aqueous methanolic extract showed significant reduction in both paw oedema models. In pain models, the extract also significantly inhibited the acetic acid-induced writhing and formalin-induced paw lickings. Our findings showed that aqueous methanolic extract of Asparagus racemosus’s root reduced inflammation and pain in experimental models. The results proposed a potential use of Asparagus racemosus’s roots in treating conditions associated with inflammation and pain.