Farmacia Journal 6/2020
Volume 68 | Number 6 | Year 2020
Download this issue’s covers and announcements.
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STUDY OF AVAILABLE ANTIVIRAL TREATMENTS FOR COVID-19 DURING PREGNANCY
OCTAVIAN GABRIEL OLARU 1#, DUMITRU CRISTINEL BADIU 1#, ANCA DANIELA STĂNESCU 1, CĂTĂLINA MONICA PENA 2, RALUCA IOANA PAPACOCEA 1*, ANDRA BALCANGIU STROESCU 1
1.“Carol Davila” University of Medicine and Pharmacy, 040292, Bucharest, Romania
2.“Ana Aslan” National Institute of Gerontology and Geriatrics, 011241, Bucharest, Romania -
NITRIC OXIDE PATHWAY AS A POTENTIAL THERAPEUTIC TARGET IN COVID-19
KHALID M. ALKHARFY, MUNEEB U REHMAN, AJAZ AHMAD *
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia
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HIGH SKIN MELANIN CONTENT, VITAMIN D DEFICIENCY AND IMMUNITY: POTENTIAL INTERFERENCE FOR SEVERITY OF COVID-19
MUHAMMAD TOREQUL ISLAM 1,2#, BAHARE SALEHI 3#, OANA KARAMPELAS 4#, JAVAD SHARIFI-RAD 5,6*, ANCA OANA DOCEA 7, MIQUEL MARTORELL 8, DANIELA CALINA 9
1.Laboratory of Theoretical and Computational Biophysics, Ton Duc Thang University, Ho Chi Minh City, Vietnam
2.Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Vietnam
3.Medical Ethics and Law Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4.Department of Pharmaceutical Technology and Biopharmaceutics, “Carol Davila” University of Medicine and Pharmacy, 020956, Bucharest, Romania
5.Facultad de Medicina, Universidad del Azuay, Cuenca, Ecuador
6.Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
7.Department of Toxicology, University of Medicine and Pharmacy of Craiova, 200349, Craiova, Romania
8.Department of Nutrition and Dietetics, Faculty of Pharmacy, and Centre for Healthy Living, University of Concepción, 4070386 Concepción, Chile
9.Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349. Craiova, Romania -
EMERGING APPLICATIONS OF SOME IMPORTANT NATURAL COMPOUNDS IN THE FIELD OF ONCOLOGY
CRISTIAN SCHEAU, LIVIA GRAȚIELA MIHAI *, IOANA ANCA BĂDĂRĂU, CONSTANTIN CĂRUNTU
Department of Physiology, “Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania
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ESSENTIAL OILS IN WELLNESS CENTERS: OVERVIEW ON EUROPEAN UNION LEGISLATION, POTENTIAL THERAPEUTIC EFFECTS AND TOXICITY
ANA FLAVIA BURLEC 1#, IRINA MACOVEI 1#, ALINA SĂCĂRESCU 2, ANDREIA CORCIOVĂ 1*, CORNELIA MIRCEA 1, CRISTINA ELENA IANCU 1, OANA CIOANCĂ 1, MONICA HĂNCIANU 1
1.Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115, Iași, Romania
2.Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115, Iași, Romania -
THE EVALUATION OF DYNAMIC COMPACTION ANALYSIS AS A QBD TOOL FOR PAEDIATRIC ORODISPERSIBLE MINITABLET FORMULATION
SONIA IURIAN *, LARISA ILIE, MARCELA ACHIM, IOAN TOMUȚĂ
Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș Street, Cluj-Napoca, 400012, Romania
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PHYTOCHEMICAL PROFILE, ANTIOXIDANT, ANALGESIC AND HYPOLIPIDAEMIC EFFECTS OF EPHEDRA ALATA DECNE. FEMALE CONES EXTRACT
ATEF CHOUIKH 1,2
1.Biology Department, Faculty of Natural Science and Life, El Oued University, Algeria
2.Laboratory Biology, Environment and Health (LBEH), El Oued University, Algeria -
ANTIBIOTIC PROPHYLAXIS IN TRANSURETHRAL RESECTIONS: WHAT ARE THE CRITERIA THAT SHOULD BE FOLLOWED?
CĂTĂLIN PRICOP 1,2#, LIGIA FLORENTINA FURTUNESCU 3#, DANIEL RĂDĂVOI 3,4*, VIOREL JINGA 3,4, ALIN CUMPĂNAȘ 5, DANA-TEODORA ANTON-PĂDURARU 6, ADELINA MIRON 2, CRISTIAN TOMA 3, DRAGOȘ PUIA 1,2
1.“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, Discipline of Urology, 16 Universităţii Street, 700115, Iaşi, Romania
2.“Dr. C. I. Parhon” Clinical Hospital, Clinic of Urology, 50 Carol I Boulevard, 700503, Iaşi, Romania
3.“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, 37 Dionisie Lupu Street, Bucharest, Romania
4.“Prof. Dr. Theodor Burghele” Clinical Hospital, Department of Urology, 20 Panduri Road, Bucharest, Romania
5.University of Medicine and Pharmacy, Faculty of Medicine, Discipline of Urology, Timișoara, Romania
6.“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, Department of Mother and Child Medicine, 16 Universităţii Street, Iaşi, Romania -
COMPARATIVE ANALYSIS OF THE RELEASE PERFORMANCE OF INDOMETHACIN FROM TRANSDERMAL THERAPEUTIC SYSTEMS
PAULA ANTONOAEA 1, MAGDALENA BÎRSAN 2*, NICOLETA TODORAN 1, EMŐKE RÉDAI 1, ROBERT ALEXANDRU VLAD 1, DANIELA-LUCIA MUNTEAN 3, AURA RUSU 4, ADRIANA CIURBA 1
1.“George Emil Paladeˮ University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, 38 Gheorghe Marinescu Street, 540139, Târgu Mureș, Romania
2.“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology, 16 Universitatii Street, 700115, Iași, Romania
3.“George Emil Paladeˮ University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Faculty of Pharmacy, Department of Analytical Chemistry and Drug Analysis, 38 Gheorghe Marinescu Street, 540139, Târgu Mureș, Romania
4.“George Emil Paladeˮ University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 38 Gheorghe Marinescu Street, 540139, Târgu Mureș, Romania -
INSIGHT INTO THE POTENTIAL INFLUENCE OF INTER- AND INTRA-INDIVIDUAL VARIABILITY OF TACROLIMUS EXPOSURE ON GRAFT FUNCTION DECLINE IN THREE-YEAR PERIOD FOLLOWING KIDNEY TRANSPLANTATION
NIKOLA Z. STEFANOVIĆ 1*, RADMILA M. VELIČKOVIĆ-RADOVANOVIĆ 2,3, KATARINA S. DANKOVIĆ 4, ALEKSANDRA K. CATIĆ-DJORDJEVIĆ 1, IVANA D. DAMNJANOVIĆ 1, BRANKA P. MITIĆ 3,5, MINA B. CVETKOVIĆ 3,4, TATJANA P. CVETKOVIĆ 3,6
1.University of Nis, Faculty of Medicine, Department of Pharmacy, 81 Dr Zorana Djindjica Boulevard, 18000, Nis, Serbia
2.University of Nis, Faculty of Medicine, Department of Pharmacology with Toxicology, 81 Dr Zorana Djindjica Boulevard, 18000, Nis, Serbia
3.Clinical Centre Nis, Clinic of Nephrology, 48 Dr Zorana Djindjica Boulevard, 18000, Nis, Serbia
4.University of Nis, Faculty of Medicine, 81 Dr Zorana Djindjica Boulevard, 18000, Nis, Serbia
5.University of Nis, Faculty of Medicine, Department of Internal Medicine, 81 Dr Zorana Djindjica Boulevard, 18000, Nis, Serbia
6.University of Nis, Faculty of Medicine, Department of Biochemistry, 81 Dr Zorana Djindjica Boulevard, 18000, Nis, Serbia -
ANTIOXIDANT ACTIVITY AND DRUG PROFILE OF SEVERAL THIOUREA DERIVATIVES OF 2-THIOPHENE CARBOXYLIC ACID
TEODORA COSTEA 1#, CARMELLINA DANIELA BĂDICEANU 2*, DIANA CAMELIA NUȚĂ 2, CERASELA ELENA GÎRD 1, CARMEN LIMBAN 2, OANA KARAMPELAS 3#, SPERANȚA AVRAM 4
1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacognosy, Phytochemistry and Phytotherapy, 6 Traian Vuia Street, Bucharest, 020956, Romania
2.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 6 Traian Vuia Street, Bucharest, 020956, Romania
3.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, 6 Traian Vuia Street, Bucharest, 020956, Romania
4.University of Bucharest, Faculty of Biology, Department of Anatomy, Animal Physiology and Biophysics, 36-46 M. Kogălniceanu Boulevard, 050107, Bucharest, Romania -
PHYSICO-CHEMICAL CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF A CONTROLLED COLLAGEN-HYDROXYAPATITE-CIPROFLOXACIN RELEASE SYSTEM
MARIA-VIORICA CIOCÎLTEU 1, OANA-LILIANA FILIP (IONESCU) 1*, COSTEL VALENTIN MANDA 1, OANA-ELENA NICOLAESCU 1, IONELA ANDREEA NEACȘU 2, ANTON FICAI 2, IULIANA-MIHAELA BUZATU 3, CLAUDIU NICOLICESCU 4, OCTAVIAN CROITORU 1, JOHNY NEAMŢU 1
1.Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rareș Street, 200349, Craiova, Romania
2.Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Polizu Street, 011061, Bucharest, Romania
3.Primary Physician, Fundeni Clinical Institute, Laboratory for Medical Analysis in the Microbiology Department, 258 Fundeni Street, 022328, Bucharest, Romania
4.Department of IMST, Faculty of Mechanics, University of Craiova, 1 Călugăreni Street, 220037, Drobeta Turnu Severin, Romania -
BIOLOGICAL ACTIVITIES AND PHYTOCHEMICAL SCREENING OF ETHANOL EXTRACTS FROM ADONIS PARYADRICA (RANUNCULACEAE)
OSMAN UCUNCU 1*, CEMALETTIN BALTACI 2, ZEYNEP AKAR 3, AZER OZAD DUZGUN 3, MUSTAFA CUCE 4, ALI KANDEMIR 5
1.Department of Food Processing, Maçka Vocational School, Karadeniz Technical University, 61750 Trabzon, Turkey
2.Department of Food Engineering, Faculty of Engineering and Natural Sciences, Gümüşhane University, 29100 Gümüşhane, Turkey
3.Department of Genetic and Bioengineering, Faculty of Engineering and Natural Sciences, Gümüşhane University, 29100 Gümüşhane, Turkey
4.Department of Food Technology, Şebinkarahisar School of Applied Sciences, Giresun University, 28400 Giresun, Turkey
5.Department of Biology, Faculty of Arts and Sciences, Erzincan Binali Yıldırım University, 24100 Erzincan, Turkey -
THE EFFICACY OF CLONIDINE IN THE PHARMACOLOGICAL MANAGEMENT OF ALCOHOL WITHDRAWAL SYNDROME: PRELIMINARY RESULTS
VIRGIL RADU ENĂTESCU 1#, RALUKA KALINOVIC 2#, CRISTINA ADRIANA DEHELEAN 3, CĂTĂLINA GIURGI-ONCU 1, LAVINIA MARIA HOGEA 1, PETRU IFTENI 4, GABRIELA VLAD 2, OANA NEDA-STEPAN 2, MIHAELA SIMU 1, OVIDIU HOREA BEDREAG 5, ILEANA MARINESCU 6, DELIA HUTANU 7, ILEANA ENĂTESCU 8*, LAURA ALEXANDRA NUSSBAUM 1
1.The 8th Department, Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
2.“Pius Brinzeu” Emergency County Hospital – Psychiatric Clinic, Timișoara, Romania
3.The 2nd Department, Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
4.Transilvania University, Brașov, Romania
5.The 10th Department, Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
6.University of Medicine and Pharmacy Craiova, Romania
7.Biology Department, West University Timișoara, Romania
8.The 12th Department, Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania -
RESEARCH ON ENZYME INHIBITION POTENTIAL AND PHENOLIC COMPOUNDS FROM ORIGANUM VULGARE SSP. VULGARE
DANIELA HANGANU 1,#, DANIELA BENEDEC 1*, NELI-KINGA OLAH 2, FLORICA RANGA 3, SIMONA MIREL 1,#, BRÎNDUȘA TIPERCIUC 1,#, ILIOARA ONIGA 1
1.“Iuliu Haţieganu” University of Medicine and Pharmacy, 8 V. Babeș Street, RO-400010, Cluj-Napoca, Romania
2.“Vasile Goldiş” Western University of Arad, 94 Revoluției Avenue, Arad, Romania
3.University of Agricultural Science and Veterinary Medicine, 3-5 Mănăștur Street, Cluj-Napoca, Romania -
APPLICATION OF TRANEXAMIC ACID FOR THE PERIOPERATIVE PERIOD OF PATIENTS UNDERGOING SCOLIOSIS CORRECTION SURGERY
WENPENG LI 1#, JINGTAO GUAN 1#, YINGXUE GUO 2, JIAZHI WANG 3, YEQIU WANG 3, YAN QU 3*
1.Orthopeadic Surgery, The Second Affiliated Hospital of Jiamusi University, Jiamusi City 154002, Heilongjiang Province, China
2.Jiamusi University, Jiamusi City 154002, Heilongjiang Province, China
3.College of Jiamusi, Heilongjiang University of Chinese Medicine, Jiamusi City 154002, Heilongjiang Province, China -
SYNTHESIS AND EVALUATION OF THE ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY OF NOVEL DIBENZOTHIEPINES
CAMELIA ELENA STECOZA 1, CONSTANTIN DRĂGHICI 2, MIRON TEODOR CĂPROIU 2, GRAȚIELA GRĂDIȘTEANU PÎRCĂLĂBIORU 3*, LUMINIȚA MĂRUȚESCU 3
1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 6 Traian Vuia Street, 020956, Bucharest, Romania
2.“Costin D. Neniţescu” Centre of Organic Chemistry Romanian Academy, 202 B Splaiul Independenţei, 060023, Bucharest, Romania
3.Research Institute of University of Bucharest, 60101, Bucharest, Romania -
ASSESSMENT OF HEAVY METALS CONTENT IN SOME MEDICINAL PLANTS AND SPICES COMMONLY USED IN ROMANIA
ELISABETA MARINESCU 1, ALINA MIHAELA ELISEI 1, ANA CLARA APROTOSOAIE 2*, OANA CIOANCĂ 2, ADRIANA TRIFAN 2, ANCA MIRON 2, SILVIA ROBU 1, CAMELIA IFRIM 4, MONICA HĂNCIANU 2
1.“Dunărea de Jos” University, Faculty of Medicine and Pharmacy, 35 Al. I. Cuza Street, Galați, Romania
2.“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Farmacy, 16 Universității Street, Iaşi, Romania
3.“Anastasie Fătu” Botanical Garden, 7-9 Dumbrava Roşie Street, Iaşi, Romania -
RENOPROTECTIVE AND HEPATOPROTECTIVE EFFECTS OF HIPPOCRATEA EXCELSA ON METABOLIC SYNDROME IN FRUCTOSE-FED RATS
ELIZABETH ALEJANDRINA GUZMÁN HERNÁNDEZ 1,2*, SILVANA ANDREA DÍAZ PORTILLO 1, ÓSCAR CRISTÓBAL VILLAFUERTE ANAYA 1, MARÍA DEL ROSARIO GONZÁLEZ VALLE 3, JOSÉ DEL CARMEN BENÍTEZ FLORES 3, RUBÉN SAN MIGUEL CHÁVEZ 4, GLADYS CHIRINO GALINDO 5, LEONARDO DEL VALLE MONDRAGÓN 6, DAVID SEGURA COBOS 2, GIL ALFONSO MAGOS GUERRERO 7, PEDRO LÓPEZ SÁNCHEZ 1
1.Postgraduate Studies and Research Section, Higher School of Medicine, National Polytechnic Institute, Mexico City, 11340, Mexico
2.Medical Surgeon Career, Faculty of Superior Studies Iztacala, National Autonomous University of Mexico, Tlalnepantla, State of Mexico, 54090, Mexico
3.Histology Laboratory, Morphology and Function Unit, Faculty of Superior Studies Iztacala, National Autonomous University of Mexico, Tlalnepantla, State of Mexico, 54090, Mexico
4.Phytochemistry Area, Postgraduate Degree in Botany, Campus Montecillo, Postgraduate College, Km. 36.5 México-Texcoco Road, Montecillo, Texcoco, State of Mexico, C.P. 56230, Mexico
5.Biology Career, Faculty of Superior Studies Iztacala, National Autonomous University of Mexico, Tlalnepantla, State of Mexico, 54090, Mexico
6.Department of Pharmacology, National Institute of Cardiology Ignacio Chávez, Mexico City, C.P. 04510, Mexico
7.Department of Pharmacology, Faculty of Medicine, National Autonomous University of Mexico, Coyoacán, Mexico City, C.P. 04510, Mexico. -
RHEOLOGICAL BEHAVIOUR AND IN VITRO RELEASE PROFILES OF NAFTIFINE TOPICAL HYDROGELS
OANA KARAMPELAS #, TEODORA DALILA BALACI #, CRISTIAN FUNIERU #, EMMA ADRIANA OZON *, MIRELA ADRIANA MITU, CĂTĂLINA ANCUȚA FIȚA, DUMITRU LUPULIASA
Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
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POLYPHENOLIC DETERMINATION FROM MEDICINAL PLANTS USED IN VETERINARY MEDICINE BY AN UHPLC-LC-MS/MS METHOD
ERZSÉBET VARGA 1, IBOLYA FÜLÖP 2*, LÉNÁRD FARCZÁDI 3, MIRCEA DUMITRU CROITORU 2
The University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, Faculty of Pharmacy, 38 Gheorghe Marinescu Street, 540142, Târgu Mureş, Romania
1.Department of Pharmacognosy and Phytotherapy,
2.Department of Toxicology and Biopharmacy,
3.Centre for Advanced Medical and Pharmaceutical Research, Laboratory of Chromatography LC/MS -
ORAL ACUTE TOXICITY AND RED BLOOD CYTOTOXICITY OF THE MEDICINAL HALOPHYTE LIMONIASTRUM GUYONIANUM LEAF EXTRACT
ABDERRAHIM BENKHALED 1, ABDERRAHMANE SENATOR 2, AMEL BOUDJELAL 1, ABDELHAKIM KHENICHE 1, AMINE BELBAHI 1,3, YASSINE RÉGGAMI 1, ASMA CHEBIKA 1, WALID SALHI 1, KHODIR MADANI 2, GIUSEPPE RUBERTO 4*
1.Department of Microbiology and Biochemistry, Faculty of Sciences, M’sila University, M’sila, Algeria
2.Laboratory of Applied Biochemistry, Faculty of Natural and Life Sciences, Ferhat Abbas-Setif University, Setif, Algeria
3.Laboratoire de Biomathématique, Biophysique, Biochimie, et Scientométrie, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, 06000 Bejaia, Algérie
4.Istituto del CNR di Chimica Biomolecolare, Via Paolo Gaifami, 18 - 95126 Catania, Italy -
THE DEVELOPMENT AND VALIDATION OF A DISABILITY AND OUTCOME PREDICTION ALGORITHM IN MULTIPLE SCLEROSIS PATIENTS
SIMONA OPREA 1, ANDREI VĂLEANU 2*, SIMONA NEGREȘ 2
1.Bucharest Emergency University Hospital, 169 Splaiul Independenței, 050098 Bucharest, Romania
2.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacology and Clinical Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania -
EVALUATION OF ALOE VERA LEAF EXTRACTS AND ALOE EMODIN ON SEVERAL CANCER CELL LINES
NURIYE AKEV 1*, EDA CANDOKEN 1, SERAP ERDEM KURUCA 2
1.Department of Biochemistry, Faculty of Pharmacy, Istanbul University, 34116, Istanbul, Turkey
2.Department of Physiology, Istanbul Faculty of Medicine, Istanbul University, 34093, Istanbul, Turkey -
COMPARISON OF MEDICAL AND PHARMACY STUDENTS’ READINESS FOR INTERPROFESSIONAL LEARNING – A CROSS-SECTIONAL STUDY
MAGDALENA CERBIN-KOCZOROWSKA 1*, PIOTR PRZYMUSZAŁA 1, MICHAŁ MICHALAK 2, SYLWIA EWA PIOTROWSKA-BRUDNICKA 3, PATRYCJA KANT 4, AGNIESZKA SKOWRON 5
1.Chair and Department of Medical Education, Poznan University of Medical Sciences, 7 Rokietnicka Street, 60-806 Poznan, Poland
2.Department of Computer Science and Statistics, Poznan University of Medical Sciences, 7 Rokietnicka Street, 60-806 Poznan, Poland
3.Department of Clinical Biomechanics and Physiotherapy in Motor System Disorders, Wroclaw Medical University, 2 Grunwaldzka Street, 50-355 Wroclaw, Poland
4.Day Lewis Pharmacy Ltd, 35 Summerfield Road, Margate CT9 3EZ, United Kingdom
5.Department of Social Pharmacy, Jagiellonian University, College of Medicine, 9 Medyczna Street, 30-688 Krakow, Poland