Romanian Society of Pharmaceutical Sciences

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EMERGING APPLICATIONS OF SOME IMPORTANT NATURAL COMPOUNDS IN THE FIELD OF ONCOLOGY

CRISTIAN SCHEAU, LIVIA GRAȚIELA MIHAI *, IOANA ANCA BĂDĂRĂU, CONSTANTIN CĂRUNTU

Department of Physiology, “Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania

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Cancer is among the leading causes of death worldwide, with several malignancies presenting an increase in their incidence, such as thyroid cancer, hepatocellular carcinoma, skin melanoma, uterine cancer, and oral cavity cancer. Phytochemicals have long been used in various fields of medicine for their properties, and the discovery of anti-tumour, anti-oxidant, and anti-inflammatory effects of some of these substances have prompted their application in the field of oncology. Several in vivo and in vitro studies have demonstrated the effectiveness of some phytochemicals on specific tumour cell lines, revealing their potential role in the complementary treatment of cancer. This paper addresses the anti-tumour and chemopreventive roles of various phytochemicals in malignancies with increasing incidence.