Farmacia Journal 2/2020
Volume 68 | Number 2 | Year 2020
Download this issue’s covers and announcements.
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A NEW ERA FOR THE THERAPEUTIC MANAGEMENT OF THE ONGOING COVID-19 PANDEMIC
ANDREEA LETIȚIA ARSENE 1#, ION-BOGDAN DUMITRESCU 1#, CRISTINA MANUELA DRĂGOI 1#, DENISA IOANA UDEANU 1*, DUMITRU LUPULIASA 1, VIOREL JINGA 1, DOINA DRĂGĂNESCU 1, CRISTINA ELENA DINU-PÎRVU 1, GEORGE TRAIAN ALEXANDRU BURCEA DRAGOMIROIU 1#, IONUȚ EMILIAN BLEJAN 1, RALUCA ELISABETA MOISI 1, ALINA CRENGUȚA NICOLAE 1, HORAȚIU MOLDOVAN 2, DANIELA ELENA POPA 1, BRUNO ȘTEFAN VELESCU 1, SIMONA RUȚĂ 1
1. “Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021, Bucharest, Romania
2. Ministry of Health, 1-3 Cristian Popişteanu Street, 010024, Bucharest, Romania -
ANTIBIOTIC RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS; MECHANISMS AND SPECIFIC THERAPEUTIC RESPONSE
GILDA GEORGETA POPESCU 1, OANA CRISTINA ARGHIR 2, ARIADNA PETRONELA FILDAN 2, VICTOR SPANU 1, SIMONA CLAUDIA CAMBREA 2, ALEXANDRU RAFILA 3*, FLORIN CORNELIU BUICU 4
1. “Marius Nasta” Pneumonology Institute, Bucharest, Romania
2. “Ovidius” University, Faculty of Medicine, Constanța, Romania
3. “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
4. University of Medicine, Pharmacy, Science and Technology, Târgu-Mureș, Romania -
OVERVIEW OF NON-VITAMIN K ORAL ANTICOAGULANTS
IULIA MĂDĂLINA CÎRSTEA 1, BOGDAN MÎNDRILĂ 1, EUGEN ȚIERANU 1*, LOREDANA MARIA ȚIERANU 2, OCTAVIAN ISTRĂTOAIE 3, CONSTANTIN MILITARU 3, IONUȚ DONOIU 1,3
1.Department of Cardiology, Emergency County Hospital, Craiova, Romania
2.Department of Obstetrics and Gynaecology, Emergency County Hospital, Craiova, Romania
3.Department of Cardiology, University of Medicine and Pharmacy of Craiova, Craiova, Romania -
THE CURRENT STAGE OF BIOTECHNOLOGICAL APPROACHES AND SYSTEMATIC REMARKS ON SOME SPONTANEOUS MEDICINAL PLANTS IN ROMANIA – REVIEW OF LITERATURE
RODICA CATANĂ *, ROXANA NICOARĂ, MARILENA ONETE
Institute of Biology Bucharest, Romanian Academy, 296 Splaiul Independenţei, 060031, Bucharest, Romania
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ADVERSE EVENTS FOLLOWING MEASLES-MUMPS-RUBELLA VACCINATION. A PROSPECTIVE OBSERVATIONAL STUDY
CAMELIA BUCȘA 1, NOEMI BULIK 2*, ANDREEA FARCAȘ 1, SANDRA MUREȘAN 3, IOAN MUREȘAN 4, OVIDIU ONIGA 2
1.“Iuliu Hațieganu” University of Medicine and Pharmacy, Drug Information Research Center, 6 Luis Pasteur Street, Cluj-Napoca, Romania
2.“Iuliu Hațieganu” University of Medicine and Pharmacy, Pharmaceutical Chemistry Department, 41 Victor Babeș Street, Cluj-Napoca, Romania
3.Sandra Muresan Medical Office, 32 Moților Street, Cluj-Napoca, Romania
4.Ioan Muresan Medical Office, 5 Grigore Alexandrescu Street, Cluj-Napoca, Romania -
SELF-MEDICATION PRACTICES AMONG THE PATIENTS WITH CHRONIC VENOUS DISEASE
IVANA DAMNJANOVIC 1*, NIKOLA STEFANOVIC 1, SNEZANA ZLATKOVIC-GUBERINIC 2, ZORAN DAMNJANOVIC 3, ALEKSANDRA CATIC-DJORDJEVIC 1, RADMILA VELICKOVIC-RADOVANOVIC 1
1.Department of Pharmacy, Faculty of Medicine, University of Nis, 81 Dr Zorana Djindjica Boulevard, 18000, Nis, Serbia
2.Health Care Institution Pharmacy Remedia Nis, 2 Obrenoviceva Street, 18000, Nis, Serbia
3.Clinic of Vascular Surgery, Clinical Centre of Nis, 48 Dr Zorana Djindjica Boulevard, 18000, Nis, Serbia -
USING GAUSSIAN PROCESSES TO STUDY TRAUMATIC BRAIN INJURY IN SHEEP
LEVON GABRIELIAN 1, NOUNE S. MELKOUMIAN 2, MAGDALENA CUCIUREANU 3*
1.Schools of Medical Sciences, University of Adelaide, and Hanson Institute Centre for Neurological Diseases, Australia
2.School of Civil, Environmental, and Mining Engineering, University of Adelaide, Australia
3.“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, Department of Morphofunctional Sciences, Iași, Romania -
STUDY ON TOLERABILITY AND EFFICACY OF PALIPERIDONE PALMITATE, OLANZAPINE PAMOATE AND RISPERIDONE LONG ACTING INJECTION IN A ROMANIAN SAMPLE OF PATIENTS WITH SCHIZOPHRENIA
VIRGIL-RADU ENĂTESCU 1,2*, CRISTINA ADRIANA DEHELEAN 1, LAURA ALEXANDRA NUSSBAUM 1, LAVINIA HOGEA 1, CLAUDIA HOMOROGAN 1,2, ILEANA ENĂTESCU 1, ION PAPAVĂ 1,2, ILEANA MARINESCU 3, PETRU IFTENI 4, MIHAELA SIMU 1, MARIAN CĂTĂLIN 1, CĂTĂLINA GIURGI-ONCU 1,2, IOAN-OVIDIU SÎRBU 1
1.“Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
2.“Pius Brînzeu” Emergency County Hospital - Psychiatric Clinic, Timișoara, Romania
3.University of Medicine and Pharmacy, Craiova, Romania
4.Transilvania University, Brașov, Romania -
PREVALENCE OF URINARY TRACT INFECTION AND ANTIMICROBIAL SUSCEPTIBILITY AMONG DIABETIC PATIENTS
DANA CARMEN ZAHA, CLAUDIA MARIA JURCA *, LUCIA GEORGETA DAINA, COSMIN MIHAI VESA, AMORIN REMUS POPA, ALEXANDRU DANIEL JURCA, MARIANA MURESAN, OTILIA MICLE
University of Oradea, Faculty of Medicine and Pharmacy, 1st December Street, 410073, Oradea, Romania
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HEPATITIS B VIRUS REACTIVATION IN PATIENTS UNDERGOING CHEMOIMMUNOTHERAPY FOR HAEMATOLOGICAL MALIGNANCIES
VIOLETA MOLAGIC 1#*, CĂTĂLIN TILIȘCAN 1,2#, CRISTINA POPESCU 1,2, VICTORIA ARAMĂ 1,2#, MIHAELA RĂDULESCU 1,2, ANA MARIA VLĂDĂREANU 2,3, ȘTEFAN SORIN ARAMĂ 1,2
1.“Prof. Dr. Matei Balș” National Institute for Infectious Diseases, 1 Dr. Grozovici Street, Bucharest, Romania
2.“Carol Davila” University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu Street, Bucharest, Romania
3.Haematology Department, University Emergency Hospital Bucharest, 169 Splaiul Independenței Street, Bucharest, Romania -
BRAIN PROTECTION AND ANTI-AMNESIC EFFECTS ASSESSMENT OF DATURA INNOXIA MILL. AQUEOUS EXTRACTS
PROSPER T. KINDA 1,6, SAMSON GUENNÉ 1, TINDANO BASILE 3, NOUFOU OUÉDRAOGO 2, MOUSSA COMPAORÉ 1, BALÉ BAYALA 3, WALTHER BILD 4*, ROMEO DOBRIN 4, CONSTANTIN TRUS 5, ALIN CIOBICĂ 7, MARTIN KIENDREBÉOGO 1
1.Laboratory of Applied Biochemistry and Chemistry (LA.BIO.C.A), University Ouaga I Pr Joseph KI-ZERBO, 03 P.O. Box: 7021 Ouagadougou 03, Burkina Faso
2.Institute for Research in Health Sciences (IRSS/CNRST), Department of Medicine and Traditional Pharmacopoeia (MEPHATRA-PH), 03 P.O. Box: 7192 Ouagadougou 03, Burkina Faso
3.Laboratory of Animal Physiology, University Ouaga I Pr Joseph KI-ZERBO, 03 P.O. Box: 7021 Ouagadougou 03, Burkina Faso
4.“Grigore T. Popa” University of Medicine and Pharmacy, 16 Universitatii Street, 700115, Iași, Romania
5.Department of Morphological and Functional Sciences, Faculty of Medicine, “Dunărea de Jos” University, Galați, Romania
6.Laboratory of Forensic Sciences, General Direction of National Police, 01 P.O. Box: 22 Ouagadougou 01, Burkina Faso
7.Department of Research, Faculty of Biology, “Alexandru Ioan Cuza” University; 11 Carol I Avenue, 700506, Iași, Romania -
THE POTENTIAL CARDIOPROTECTIVE EFFECT OF MATRICARIA CHAMOMILLA EXTRACT AGAINST DIABETES-INDUCED OXIDATIVE STRESS IN RATS
GAMAL A. SOLIMAN 1,2, SHERIF A. ABDEL-GAWAD 3,4, MOHD N. ANSARI 1*, ABDUL-MALEK S. ALTAMIMI 3, HOSSNY A. EL-BANNA 2, HISHAM Y. ELZORBA 2, NOHA F. HASSAN 5
1.Department of Pharmacology, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia
2.Department of Pharmacology, College of Veterinary Medicine, Cairo University, Egypt
3.Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia
4.Department of Analytical Chemistry, College of Pharmacy, Cairo University, Egypt
5.Global Pharma Factory, Cairo, Egypt -
GC-MS ANALYSIS AND BIOACTIVE PROPERTIES OF ZINGIBERIS RHIZOMA ESSENTIAL OIL
LAURA BUCUR 1#, ELIS IONUS 2*, GEORGETA MOISE 3#, CERASELA GÎRD 4#, VERGINICA SCHRÖDER 5
1.Pharmacognosy Department, Faculty of Pharmacy, “Ovidius” University of Constanța, Romania
2.Organic Chemistry Department, Faculty of Pharmacy, “Ovidius” University of Constanța, Romania
3.Scient Research Centre for Instrumental Analysis, 1 Petre Ispirescu Street, Tâncăbeşti, Romania
4.Pharmacognosy Department, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
5.Cellular and Molecular Biology Department, Faculty of Pharmacy, “Ovidius” University of Constanța, Romania -
SYMMETRICAL AND ASYMMETRICAL MESO-SUBSTITUTED PORPHYRINS AND Zn-METALLOPORPHYRINS IN GOLD COLLOID ENVIRONMENT. OPTICAL PROPERTIES AND EVALUATION OF ANTIBACTERIAL ACTIVITY
LUMINIȚA SALAGEANU 1,2, DELIA MUNTEAN 3,4*, MONICA LICKER 3,4, ANCA LASCU 1, DIANA ANGHEL 1, EUGENIA FAGADAR-COSMA 1
1.Institute of Chemistry, Romanian Academy, 24 Mihai Viteazul Avenue, 300223, Timișoara, Romania
2.Health Insurance House Timiș, 4 Corbului Street, 300239, Timișoara, Romania
3.“Victor Babeș” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
4.“Pius Brînzeu” Emergency Clinical County Hospital, 156 Liviu Rebreanu Boulevard, 300723, Timișoara, Romania -
COMPARATIVE HEPATOPROTECTIVE EFFICACY OF SILYMARIN-PHYLLANTHUS-CHOLINE COMBINATION VERSUS SILYMARIN ALONE IN LIVER DISEASES WITH DIFFERENT DESTRUCTION AND INFLAMMATION STAGES
OVIDIU FRĂȚILĂ 1*, ADINA IOANA MIHELE 2, EVA FLORINA HODISAN-PAP 2, SERGIU CRISTIAN HOCOPAN 2, ROXANA BRATA 1, TIBERIA ILIAȘ 1
1.Department of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, Romania
2.University of Oradea, Romania -
EFFECTS OF CURCUMIN ON INHIBITING THE PROLIFERATION OF PULMONARY ARTERY SMOOTH MUSCLE CELLS AND RELIEVING PULMONARY ARTERIAL HYPERTENSION
YUNHUI GUO 1, BAIZHU AN 2, ZHIFANG LANG 3, FUBO ZHOU 4*, XINHUA ZHANG 5, HUAILIANG WANG 5
1.Department of Pharmacology, College of Jiamusi, Heilongjiang University of Chinese Medicine, Jiamusi 154007, China
2.Department of Anatomy, Mudanjiang Medical University, Mudanjiang 157011, China
3.Department of Medical Function, Mudanjiang Medical University, Mudanjiang 157011, China
4.Department of Pharmacology, Mudanjiang Medical University, Mudanjiang 157011, Heilongjiang Province, China
5.Department of Clinical Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, Liaoning Province, China -
SPONGIOUS FILLERS BASED ON COLLAGEN – HYDROXYAPATITE – EUGENOL ACETATE WITH THERAPEUTIC POTENTIAL IN BONE CANCER
ALINA F. VLADU 1, STEFANIA MARIN 2,3, IONELA A. NEACȘU 1, ROXANA D. TRUŞCĂ 1, MĂDĂLINA G. ALBU KAYA 2, DURMUS A. KAYA 4, ANA-MARIA POPA 5, CĂTĂLINA POIANĂ 6, IOAN CRISTESCU 6*, CRISTINA ORLOV 5, DENISA FICAI 1, ANTON FICAI 1,7, DENISA I. UDEANU 6, BRUNO ȘTEFAN VELESCU 6, TAXIARCHIS KONSTANTINOS NIKOLOUZAKIS 8, LEONID GUREVICH 9, ANDREY N. KUSKOV 10,11, CORNELIA NIȚIPIR 5,6
1.University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, 060042, Bucharest, Romania
2.Collagen Department, Division Leather and Footwear Research Institute, National Research and Development Institute for Textile and Leather, 031215 Bucharest, Romania
3.Center of Surface Science and Nanotechnology, University Politehnica of Bucharest, 060042 Bucharest, Romania
4.Department of Field Crops, Agriculture Faculty, Hatay Mustafa Kemal University, Antakya, Turkey
5Clinic of Medical Oncology, Elias University Emergency Hospital, Bucharest, Romania
6.“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
7.Academy of Romanian Scientists, Bucharest, Romania
8.Laboratory of Toxicology, University of Crete, Voutes, Heraklion, Crete, Greece
9.Department of Materials & Production, Aalborg University, Skjernvej 4A, Aalborg, Denmark
10.Department of Technology of Chemical Pharmaceutical and Cosmetic Products, D. Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
11.Department “Chembiotech”, Moscow Polytechnic University, Moscow, Russian Federation -
ASSESSMENT OF ANTIOXIDANT PROPERTIES OF DIFFERENT FOMES FOMENTARIUS EXTRACTS
LORETA-ANDREA BOJIN 1#, ALINA-FLORINA SERB 1#, MIHAI-COSMIN PASCARIU 2,3#, ALINA MOACA 4, ROXANA KOSTICI 5, VICTOR LORIN PURCĂREA 6, MIRCEA PENESCU 6, MIHAELA VIVIANA IVAN 1, MARIUS GEORGESCU 1*, EUGEN SISU 1
1.“Victor Babeş” University of Medicine and Pharmacy Timişoara, Faculty of Medicine, 2 Eftimie Murgu Square, 300041, Timişoara, Romania
2.“Vasile Goldis” Western University of Arad, Faculty of Pharmacy, 86 Liviu Rebreanu Street, 310414, Arad, Romania
3.Institute of Research & Development for Electrochemistry and Condensed Matter, 300569 Timișoara, Romania
4.“Victor Babes” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Toxicology, 2 Eftimie Murgu Square, 300041 Timişoara, Romania
5.University of Medicine and Pharmacy Craiova, Faculty of Pharmacy, 2 Petru Rareş Street, 200349, Craiova, Romania
6.“Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021, Bucharest, Romania -
THE ANTIOXIDANT POTENTIAL EVALUATION OF DICLOFENAC DERIVATIVES WITH HYDRAZONES STRUCTURE
ALIN FOCȘA 1, ANDREEA IACOB 1, IOANA VASINCU 1, SANDRA CONSTANTIN 1, LOREDANA ANDRIESCU 1, ALEXANDRU SAVA 1, FRÉDÉRIC BURON 2, SYLVAIN ROUTIER 2, LENUŢA PROFIRE 1*
1.Department of Pharmaceutical Chemistry, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115, Iaşi, Romania
2.Institute of Organic and Analytical Chemistry, University of Orléans - Pôle de Chimie, Chartres Street, 45067, Orléans, France -
ALLICIN DIVERSITY IN SOME WILD POPULATION OF SIX ALLIUM SPECIES FROM IRAN
MAHBOOBEH ZARE MEHRJERDI 1*, MAHDI MORIDI FARIMANI 2, JALAL REZAEI 1, HASSAN MASTALI 1
1.Department of Horticulture, Aburaihan Campus, University of Tehran, Tehran, Iran
2.Department of Phytochemistry, Medicinal Plants and Drug Research Institute, Shahid Beheshti University, Tehran, Iran -
CHEMICAL COMPOSITION, ANTIOXIDANT ACTIVITY AND CYTOTOXIC EFFECTS OF ROMANIAN CRATERELLUS CORNUCOPIOIDES (L.) PERS. MUSHROOM
TEODORA COSTEA 1#, ARIANA HUDIŢĂ 2#, OCTAVIAN TUDOREL OLARU 3#, BIANCA GĂLĂŢEANU 2*, CERASELA ELENA GÎRD 1, MARIA-MAGDALENA MOCANU 4
1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacognosy, Phytochemistry and Phytotheraphy, 020956 Bucharest, Romania
2.University of Bucharest, Department of Biochemistry and Molecular Biology, 050095 Bucharest, Romania
3.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Botany and Cellular Biology, 020956 Bucharest, Romania
4.“Carol Davila” University of Medicine and Pharmacy, Department of Biophysics, 050474 Bucharest, Romania -
BIOACTIVITY SCREENING AND ISOLATION OF THREE FATTY ACID ETHYL ESTERS FROM ANEMONIA VIRIDIS
HAJAR HEYDARI 1, EMILIANO MANZO 2, BULENT GOZCELIOGLU 3, BELMA KONUKLUGIL 1*
1.Pharmacognosy Department of Ankara University, Ankara, Turkey
2.Institute of Biomolecular Chemistry, Naples, Italy
3.Scientific and Technological Research Council of Turkey (TÜBITAK), Ankara, Turkey -
PERSPECTIVES TO DESCRIBE SURFACE PROPERTIES OF RAW PHARMACEUTICAL MATERIALS. A FRACTAL APPROACH ON THE WETTING OF POWDERS
RĂZVAN MIHAI PRISADA 1#, CRISTINA-ELENA DINU-PÎRVU 1#, HORAȚIU MOLDOVAN 2#, MIHAELA VIOLETA GHICA 1*, ROXANA-ELENA AVRĂMESCU 1, LĂCRĂMIOARA POPA 1
1.“Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, România
2.University Politehnica of Bucharest, 313 Splaiul Independenţei, 060042, Bucharest, Romania -
HOMOLOGY MODEL, DOCKING ANALYSIS AND MOLECULAR DYNAMICS SIMULATION OF CANNABINOID CB2 RECEPTOR
WEIDONG XU 1#, QIAOLI LV 2#, YA LIU 1, XIAOPING LAI 1, FEN LIU 1, GUOGANG TU 1*
1.Department of Medicinal Chemistry, School of Pharmaceutical Science, NanChang University, 330006, China
2.Department of Science and Education, JiangXi Key Laboratory of Translational Cancer Research, JiangXi Cancer Hospital, 330029, China -
SOCIODEMOGRAPHIC FACTORS’ INFLUENCE ON ADHERENCE TO ANTIHYPERTENSIVE MEDICATION
CRISTINA DANIELA MARINECI, CORNEL CHIRIȚĂ *, ANDREI VĂLEANU, CRISTINA ELENA ZBÂRCEA, SIMONA NEGREȘ
“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacology and Clinical Pharmacy, Bucharest, Romania