Romanian Society of Pharmaceutical Sciences

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ASSESSMENT OF ANTIOXIDANT PROPERTIES OF DIFFERENT FOMES FOMENTARIUS EXTRACTS

LORETA-ANDREA BOJIN 1#, ALINA-FLORINA SERB 1#, MIHAI-COSMIN PASCARIU 2,3#, ALINA MOACA 4, ROXANA KOSTICI 5, VICTOR LORIN PURCĂREA 6, MIRCEA PENESCU 6, MIHAELA VIVIANA IVAN 1, MARIUS GEORGESCU 1*, EUGEN SISU 1

1.“Victor Babeş” University of Medicine and Pharmacy Timişoara, Faculty of Medicine, 2 Eftimie Murgu Square, 300041, Timişoara, Romania
2.“Vasile Goldis” Western University of Arad, Faculty of Pharmacy, 86 Liviu Rebreanu Street, 310414, Arad, Romania
3.Institute of Research & Development for Electrochemistry and Condensed Matter, 300569 Timișoara, Romania
4.“Victor Babes” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Toxicology, 2 Eftimie Murgu Square, 300041 Timişoara, Romania
5.University of Medicine and Pharmacy Craiova, Faculty of Pharmacy, 2 Petru Rareş Street, 200349, Craiova, Romania
6.“Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021, Bucharest, Romania

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Ten extracts of the wild, inedible mushroom Fomes fomentarius obtained with different solvents: water, 80% ethanol, absolute ethanol, acetone, methanol, petroleum ether, cyclohexane, hexane, toluene and dichlormethane, were evaluated for their free radical scavenging capacity by DPPH (2.2-diphenyl-1-picryl-hydrazyl-hydrate) assay. Methanol and ethanol extracts showed the highest antioxidant activity (AOA) independent of the concentration of DPPH ethanolic solution which was used, while aqueous and petroleum ether extracts have provided increased AOAs only when the DPPH ethanolic solution concentration was decreased. Thus, the present results show that this wild inedible mushroom has good potential as a source of natural antioxidants to be used in food industry, medicine and dermatocosmetics.