Romanian Society of Pharmaceutical Sciences

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SOCIODEMOGRAPHIC FACTORS’ INFLUENCE ON ADHERENCE TO ANTIHYPERTENSIVE MEDICATION

CRISTINA DANIELA MARINECI, CORNEL CHIRIȚĂ *, ANDREI VĂLEANU, CRISTINA ELENA ZBÂRCEA, SIMONA NEGREȘ

“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacology and Clinical Pharmacy, Bucharest, Romania

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Non-adherence to antihypertensive medication is commonly associated with suboptimal clinic outcomes but is nonetheless a common behaviour. This observational study investigated medication adherence of hypertensive Romanian patients using the Morisky-Green-Levine questionnaire. 22.2% of patients had low adherence, 51.3% of patients had moderate adherence and 26.5% had high adherence. Investigating the influence of age, sex, education, medication regimen complexity, comorbidities and information about medicines offered by the pharmacist to the patient on adherence levels, the most important positive predictor of adherence was the educational level. For patients having finished secondary school and patients with primary school, odd ratios to be in a higher category of adherence, compared to university graduates, were 0.62 and 0.53 respectively. Another significant predictor of adherence was the drug regimen, the increasing number of daily medicines and nutritive supplements reducing adherence.