Romanian Society of Pharmaceutical Sciences

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PREVALENCE OF URINARY TRACT INFECTION AND ANTIMICROBIAL SUSCEPTIBILITY AMONG DIABETIC PATIENTS

DANA CARMEN ZAHA, CLAUDIA MARIA JURCA *, LUCIA GEORGETA DAINA, COSMIN MIHAI VESA, AMORIN REMUS POPA, ALEXANDRU DANIEL JURCA, MARIANA MURESAN, OTILIA MICLE

University of Oradea, Faculty of Medicine and Pharmacy, 1st December Street, 410073, Oradea, Romania

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The aim of this study was to characterize the prevalence of urinary tract infections (UTIs) in patients with diabetes mellitus, antimicrobial susceptibility pattern of the isolates and to explore the relationship with glycaemic balance. 1046 patients with diabetes, 84 with type 1 and 962 with type 2 diabetes were enrolled in the study. Each urine sample obtained by midstream collection was evaluated using dipstick and microscopical evaluation of the sediment, followed by uroculture. Most patients were diagnosed with type 2 diabetes, and the incidence of UTIs was 29.82%. The predominant isolates were E. coli and K. pneumoniae, followed by E. faecalis. The first two isolates were susceptible to cephalosporins, aminoglycosides, carbapenems, combinations with clavulanic acid or sulbactam, less to quinolones and resistant to ampicillin. Isolates strains of E. faecalis have shown a good sensitivity to antibiotics. No difference was noted between the samples with E. coli, K. pneumoniae and E. faecalis in terms of glycaemic balance.