Farmacia Journal 2/2015
Volume 63 | Number 2 | Year 2015
Download this issue’s covers
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MIGRAINE, A GRAVE FORM OF HEADACHE: A REVIEW ON CURRENT AND PERSPECTIVE RESEARCH
NISHANTH KANDEPEDU1,3*, ISABELLE ABRUNHOSA THOMAS2,3, YVES TROIN2,3
1.Clermont Université, Université Blaise Pascal, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000 Clermont- Ferrand, France
2.Clermont Université, ENSCCF, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000 Clermont-Ferrand, France
3.CNRS, UMR 6296, ICCF, F-63171 Aubiere, France -
SYNTHESIS OF SOME NEW 4-METHYL-2-(4-PYRIDYL)-THIAZOLE- 5-YL-AZOLES AS POTENTIAL ANTIMICROBIAL AGENTS
SMARANDA ONIGA1, MIHAELA DUMA2, OVIDIU ONIGA1*, BRINDUSA TIPERCIUC1, ADRIAN PIRNAU3, CĂTĂLIN ARANICIU1, MARIANA PALAGE1
1.Iuliu Hatieganu University of Medicine and Pharmacy, Dept. of Therapeutic Chemistry, 12 Ion Creanga Street, 400010 Cluj-Napoca, Romania
2.State Veterinary Laboratory for Animal Health and Food Safety, 1 Marasti Square, 400117, Cluj-Napoca, Romania
3.National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath Street, 400293 Cluj-Napoca, Romania -
CELL MEMBRANE GPER AND ERα ON MYOMETRIUM: TWO DISTINCT RECEPTORS WITH DISTINCT SIGNALLING PATHWAYS
OANA SORINA TICA1, ELENA DELIU2, TUDOREL CIUREA3,4, XIN GAO5, ANA-MARIA BUGA6,7, EUGEN OSIAC6,8, DRAGOS ALEXANDRU6,9, ANDREI ADRIAN TICA6,10*
1.Department of Mother and Child, University of Medicine and Pharmacy of Craiova, Romania
2.Department of Pharmacology, School of Medicine, Temple University of Philadelphia, USA
3.Research Centre of Gastroenterology and Hepatology, University of Medicine and Pharmacy of Craiova, Romania
4.Gastroenterology Department, University of Medicine and Pharmacy of Craiova, Romania
5.Neuroinflammation DPU GSK R&D, Shanghai, China
6.Research Centre for Clinical and Experimental Medicine, University of Medicine and Pharmacy of Craiova, Romania
7.Biochemistry Department, University of Medicine and Pharmacy of Craiova, Romania
8.Biophysics Department, University of Medicine and Pharmacy of Craiova, Romania
9.Biostatistics Department, University of Medicine and Pharmacy of Craiova, Romania
10.Pharmacology Department, University of Medicine and Pharmacy of Craiova, Romania -
THE ROLE OF α1-BLOCKERS IN THE MEDICAL EXPULSIVE THERAPY FOR URETERAL CALCULI – A PROSPECTIVE CONTROLLED RANDOMIZED STUDY COMPARING TAMSULOSIN AND SILODOSIN
DRAGOŞ GEORGESCU1, FLORENTINA IONIŢĂ-RADU2*, RĂZVAN MULŢESCU1, MIHAI DRAGUŢESCU1, BOGDAN GEAVLETE1, PETRIŞOR GEAVLETE1, CAROLINA NEGREI3, DAN MISCHIANU4, MARA GEORGESCU5, OCTAV GINGHINA6
1.”Sf. Ioan” Hospital, Department of Urology, “Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, 13, Vitan-Barzesti Street, 042122, Bucharest, Romania
2.Central Universitary Emergency Military Hospital, “Carol Davila’’- Department of Gastroenterology
3.Department of Toxicology, “Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6, Traian Vuia Street, 020956, Bucharest, Romania
4.Universitary Emergency Central Military Hospital Bucharest, Department of Urology, “Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, 134, Calea Plevnei Street, 010825, Bucharest, Romania
5.University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Mărăşti Blvd, 011464, Veterinary Medicine Faculty of Bucharest, Bucharest, Romania
6.”Sf. Ioan” Hospital, Department of Oncological Surgery, “Carol Davila” University of Medicine and Pharmacy, Faculty of Dental Medicine, 13, Vitan-Barzesti Street, 042122, Bucharest, Romania -
POSSIBLE SUBSTITUTES FOR NIMESULIDE: THE RESULTS OF A COMPREHENSIVE SCREENING BASED ON STRUCTURAL SIMILARITY AND DOCKING SIMULATION ON THE SURFACE OF ENZYMES
LÁSZLÓ FERENCZ1*, DANIELA LUCIA MUNTEAN2
1.Sapientia Hungarian University of Transylvania, Faculty of Technical and Human Sciences, Str. Sighişoarei 1C, Tîrgu-Mureş – Corunca, 540485, Romania
2.University of Medicine and Pharmacy Tîrgu-Mureș, Faculty of Pharmacy, Str. Gh. Marinescu, 38, Tîrgu-Mureș, 540139, Romania -
THE INFLUENCE OF CONTROLLER THERAPY ON CORRELATION BETWEEN FeNO AND ASTHMA CONTROL IN CHILDREN
EUGENIA BUZOIANU1,2*, MARIANA MOICEANU2, FELICIA CORA1,2, DOINA ANCA PLESCA1,2
1University of Medicine and Pharmacy „Carol Davila”, 37 Dionisie Lupu Street, Bucharest
2Department of Pediatrics and Pediatric Neurology, „Victor Gomoiu” Children Clinical Hospital, 21 Basarabia Avenue, Bucharest -
ANTIMICROBIAL RESISTANCE OF ESKAPE-PATHOGENS IN CULTURE-POSITIVE PNEUMONIA
ADRIANA SLAVCOVICI1, CODRUTA MAIER2, AMANDA RADULESCU3*
1.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Medicine, Department Medical Specialties - Infectious Diseases, 8 Victor Babeş, 400012 – Cluj-Napoca, Hospital of Infectious Diseases, Cluj-Napoca, Romania
2.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department 3 – Drug analysis, 8 Victor Babeş, 400012 - Cluj-Napoca, Romania
3.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Medicine, Department Community Medicine – Epidemiology, 8 Victor Babeş, 400012 – Cluj-Napoca, Hospital of Infectious Diseases, Cluj-Napoca, Romania -
EFFECTS OF TWO IMIDAZOLINE RECEPTOR ANTAGONISTS IN SPONTANEOUS BEHAVIOUR IN RATS
GABRIELA RUSU1, CATALINA ELENA LUPUSORU1*, LILIANA MITITELU TARTAU1, GRATIELA POPA2, NELA BIBIRE3, RAOUL VASILE LUPUSORU4, ANA-CATERINA CRISTOFOR1, MIHAI NECHIFOR1
1.University of Medicine and Pharmacy ‘Grigore T. Popa’, Faculty of Medicine, Department of Pharmacology-Algesiology, Universitatii St. no. 16, code 700115, Iasi, Romania
2.University of Medicine and Pharmacy ‘Grigore T. Popa’, Faculty of Pharmacy, Department of Pharmaceutical Technology, Universitatii St. no. 16, code 700115, Iasi, Romania
3.University of Medicine and Pharmacy ‘Grigore T. Popa’, Faculty of Pharmacy, Department of Analytical Chemistry, Universitatii St. no. 16, code 700115, Iasi, Romania
4.University of Medicine and Pharmacy ‘Grigore T. Popa’, Faculty of Medicine, Department of Patho-Physiology, Universitatii St. no. 16, code 700115, Iasi, Romania -
COMPARATIVE IN VITRO DRUG RELEASE EVALUATIONS OF NEW HYDROGELS CONTAINING OXICAMS
FLAVIAN ȘTEFAN RĂDULESCU1, DALIA SIMONA MIRON2, DOINA DRĂGĂNESCU2*, SILVIA MARIA STOICESCU3, ANA ANDREEA STĂNESCU4, ADRIAN COSMIN ROȘCA5
University of Medicine and Pharmacy „Carol Davila” Bucharest, Faculty of Pharmacy, 6th Traian Vuia Street, 020956, Bucharest, Romania
1.Department of Drug Industry and Pharmaceutical Biotechnologies
2.Department of Pharmaceutical Physics and Informatics
3.Department of Obstetrics and Gynecology, Polizu Clinical Hospital, Faculty of Medicine
4.Department of Pharmaceutical Technology and Biopharmaceutics
5.Ovidius University Constanta, Faculty of Pharmacy, Department of Drug Analysis -
SPECTRAL AND PHOTOCHEMICAL PROPERTIES OF HYPERBRANCHED NANOSTRUCTURES BASED ON GARDIQUIMOD AND TPPS4
DANIEL BODA1#, CAROLINA NEGREI2#*, ANDREEA-LETIŢIA ARSENE2#, CONSTANTIN CĂRUNTU3,4#, DUMITRU LUPULEASA2#, RODICA-MARIANA ION5,6#
1.Dermato-oncology Excellence Research Centre “Carol Davila” University of Medicine and Pharmacy, 22-24, Gr. Manolescu Street, Bucharest, Romania
2.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, Bucharest, Romania
3.Immunology Department, "Victor Babes” National Institute of Pathology, 99-101 Splaiul Independentei Street Bucharest, Romania
4.Department of Physiology, “Carol Davila” University of Medicine and Pharmacy, 8 Blvd. Eroii Sanitari, Bucharest, Romania
5.National Institute of Research&Development for Chemistry and Petrochemistry - ICECHIM, 202 Splaiul Independentei Street, Bucharest, Romania
6.Valahia University, Targoviste, Romania, Materials Engineering Dept. 18-20 Blvd. Unirii, Targoviste, Romania -
LIPOSOMAL NANODELIVERY SYSTEM FOR PROTEASOME INHIBITOR ANTICANCER DRUG BORTEZOMIB
ALINA BUTU1, STELIANA RODINO1*, DIANA GOLEA1, MARIAN BUTU1, MONICA BUTNARIU2, CONSTANTA NEGOESCU2, CRISTINA-ELENA DINU-PÎRVU3
1.National Institute of Research and Development for Biological Sciences, Splaiul independentei 296, 060031, Bucharest, Romania
2.Banat’s University of Agricultural Sciences and Veterinary Medicine "Regele Mihai I al Romaniei" from Timisoara, Calea Aradului 119, 300645, Timisoara, Romania
3.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Physical and Colloidal Chemistry Department, Traian Vuia 6, 020956, Bucharest, Romania -
ASSESSING BIOCHEMICAL AND OXIDATIVE STRESS PARAMETERS AFTER VAGINAL AND ORAL ADMINISTRATION OF 5-FLUOROURACIL IN LABORATORY ANIMALS
DANIELA-CRISTINA DIMITRIU1, CATALINA-ELENA LUPUSORU2, ILEANA COJOCARU3*, CARMEN GAFITANU3, LAURA PALADE3, RAOUL-VASILE LUPUSORU4
“Gr. T. Popa” University of Medicine and Pharmacy, Iaşi, Romania
1.Biochemistry Department
2.Pharmacology Department
3.Pharmaceutical Technology and Biopharmacy Department
4.Physiopathology Department -
FORMULATION, OPTIMIZATION AND IN VITRO EVALUATION OF RAPID DISINTEGRATING AND MUCOADHESIVE SUBLINGUAL TABLETS OF LORAZEPAM
JALEH VARSHOSAZ*, FARZIN FIROZIAN, ERFANEH GHASSAMI
Department of Pharmaceutics, School of Pharmacy and Novel Drug Delivery Systems Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran
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PHYTOCHEMICAL AND PHYTOBIOLOGICAL RESEARCH UPON AERIAL PARTS AND SEEDS FROM PEUCEDANUM OFFICINALE L.
CERASELA ELENA GÎRD, TEODORA COSTEA*, IOANA NENCU, MARIA LIDIA POPESCU, LIGIA ELENA DUŢU
University of Medicine and Pharmacy ”Carol Davila”, Faculty of Pharmacy, Pharmacognosy, Phytochemistry, Phytotherapy Department, 6 Traian Vuia Street, 020956, Bucharest, Romania
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COMBINING HETEROLOGOUS BACTERIAL EXPRESSION SYSTEM WITH AFFINITY CHROMATOGRAPHY PURIFICATION TO OBTAIN NATIVE MOUSE TYROSINASE
GABRIELA N. CHIRIȚOIU1*#, CRISTIAN V.A. MUNTEANU1#, NICULINA MITREA2
1.Institute of Biochemistry of the Romanian Academy
2.Department of Biochemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy -
HISTO-ANATOMICAL RESEARCHES ON THE VEGETATIVE ORGANS OF FIVE ROMANIAN FUMARIA SPECIES
RAMONA PĂLTINEAN, GIANINA CRIŞAN*, GEORGETA BALICA, IRINA IELCIU, CRISTINA ŞTEFĂNESCU, MIRCEA TĂMAŞ
Department of Pharmaceutical Botany, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
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ASSESSMENT OF ANTIOXIDANT CAPACITY OF SOME EXTRACTS FOR FURTHER USE IN THERAPY
LAURA VICAȘ1, ALIN TEUȘDEA2, SIMONA VICAȘ2*, ELEONORA MARIAN1, JURCA TUNDE1, MARIANA MUREȘAN1, FELICIA GLIGOR3
1.University of Oradea, Medicine and Pharmacy Faculty, Oradea, Romania
2.University of Oradea, Faculty of Environmental Protection, Oradea, Romania
3.University Lucian Blaga Sibiu, The Faculty of Medicine, Sibiu, Romania -
CONTRIBUTIONS TO THE ANTIMICROBIAL AND ANTIFUNGAL STUDY OF THE AQUEOUS EXTRACT OF PRUNUS SPINOSA L.
GABRIELA GEGIU1*, ANDREI-DAN BRANZA1, LAURA BUCUR2, MIRCEA GRIGORIAN3, TRAIAN TACHE4, VICTORIA BADEA1
1.Department of Microbiology, Ovidius University Constanta, Faculty of Dental Medicine, 7 Ilarie Voronca Street, Constanta, Romania
2.Department of Pharmacognosy, Ovidius University Constanta, Faculty of Pharmacy, 1 University Street, Campus, Building B, Constanta, Romania
3.Department of Physiology, Ovidius University Constanta, Faculty of Dental Medicine, 7 Ilarie Voronca Street, Constanta, Romania
4.Department of Semiology, Ovidius University Constanta, Faculty of Pharmacy, 1 University Street, Campus, Building B, Constanta, Romania
Department of Microbiology, Ovidius University Constanta, Faculty of Dental Medicine, 7 Ilarie Voronca Street, Constanta, Romania -
THE INFLUENCE OF SPLITTING ON THE IN VITRO RELEASE OF METOPROLOL SUCCINATE FROM SCORED TABLETS
GEORGE TRAIAN ALEXANDRU BURCEA DRAGOMIROIU1, OCTAV GINGHINĂ2, DALIA SIMONA MIRON3*, MARIA BÂRCĂ1, DANIELA ELENA POPA1, MIRCEA HÎRJĂU4, DUMITRU LUPULEASA4, FLAVIAN ȘTEFAN RĂDULESCU5
1.University of Medicine and Pharmacy “Carol Davila” Bucharest, Faculty of Pharmacy, Department of Drug Control, 6 Traian Vuia street, 020956, Bucharest, Romania
2.University of Medicine and Pharmacy “Carol Davila” Bucharest, Faculty of Dental Medicine, Department of Oncological Surgery, „Sf. Ioan” Hospital, 13 Vitan-Bârzești street, 042122, Bucharest, România
3.University of Medicine and Pharmacy “Carol Davila” Bucharest, Faculty of Pharmacy, Department of Pharmaceutical Physics and Informatics, 6 Traian Vuia street, 020956, Bucharest, Romania
4.University of Medicine and Pharmacy “Carol Davila” Bucharest, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmaceutics, 6 Traian Vuia street, 020956, Bucharest, Romania
5.University of Medicine and Pharmacy “Carol Davila” Bucharest, Faculty of Pharmacy, Department of Drug Industry and Pharmaceutical Biotechnologies, 6 Traian Vuia street, 020956, Bucharest, Romania -
TERNARY SOLID DISPERSIONS OF OXICAMS: DISSOLUTION AND PERMEABILITY STUDY
IBOLYA FÜLÖP1, ÁRPÁD GYÉRESI2, MÁRIA A. DELI4, LÓRÁND KISS4, MIRCEA DUMITRU CROITORU1*, PIROSKA SZABÓ-RÉVÉSZ3, ZOLTÁN AIGNER3
1.University of Medicine and Pharmacy, Târgu Mureş, Faculty of Pharmacy, Department of Toxicology and Biopharmacy, Gheorghe Marinescu 38, 540139, Târgu Mureş, Romania
2.University of Medicine and Pharmacy, Târgu Mureş, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Gheorghe Marinescu 38, 540139, Târgu Mureş, Romania
3.University of Szeged, Faculty of Pharmacy, Department of Pharmaceutical Technology, Eötvös 6, 6720, Szeged, Hungary
4.Laboratory of Molecular Neurobiology, Institute of Biophysics, Biological Research Centre, Temesvári krt. 62, 6726, Szeged, Hungary -
PRELIMINARY ASSESSMENT OF HEAVY METALS CONTENT OF VEGETABLES GROWN IN INDUSTRIAL AREAS IN ROMANIA
MIRELA NEDELESCU1, DAN BĂLĂLĂU2, DANIELA BACONI2*, MIHAI JULA3, DALIA MORAR3, ALINA GLIGOR3, CRISTIAN BĂLĂLĂU4
1.Hygiene and Environmental Health Department, University of Medicine and Pharmacy “Carol Davila”, Bucharest
2.Toxicology Department, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila”, Bucharest
3.Hunedoara Sanitary Veterinary and Food Safety Directorate, Deva, Hunedoara County
4.Department of General Surgery, University of Medicine and Pharmacy “Carol Davila”, Emergency Universitary Hospital “St. Pantelimon”, Bucharest -
IN VITRO MODEL FOR TOTAL ANTIOXIDANT ACTIVITY EVALUATION WITH APPLICATIONS ON BIOLOGICAL PRODUCTS
ALINA MONICA MIFTODE1, ALINA ŞTEFANACHE1*, ADRIAN ŞPAC2, VASILE DORNEANU3
“Gr. T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy, 16 Universităţii Street, 700115 Iaşi, Romania
1.Inorganic Chemistry Department;
2.Physical Chemistry Department;
3.Analytical Chemistry Department. -
EFFICACY OF INDACATEROL, A MODERN ULTRALONG-ACTING BRONCHODILATOR, IN ELDERLY PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
SORIN BERBECARU–IOVAN1, ANCA BERBECARU–IOVAN2*, ELENA CAMELIA STĂNCIULESCU2, IULIANA CEAUŞU3, GABRIELA RĂU2, CĂTĂLINA GABRIELA PISOSCHI2
1.Faculty of Medicine, University of Medicine and Pharmacy, 2 Petru Rareş, 200349, Craiova, Romania,
2.Faculty of Pharmacy, University of Medicine and Pharmacy, 2 Petru Rareş, 200349, Craiova, Romania,
3.Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila”, Dr. Ion Cantacuzino Hospital, 5-7 Ion Movilă, Bucharest, Romania -
INFLUENCE OF ENVIRONMENTAL CHLOROFORM CONCENTRATIONS ON BIOPHYSICS SKIN PARAMETERS
DANIELA CIORBA1*, ALEXANDRU TATARU3, ADRIAN AVRAM3, ALEXANDRA ALMASI4, MIRELA MOLDOVAN2
1.Environment Science Faculty, Babes-Bolyai University, Cluj-Napoca, Romania
2.Iuliu Hatieganu University, Medicine Faculty, Dermatologic Clinic, Cluj-Napoca, Romania
3.Science Faculty, Aalborg University, Aalborg, Danemark
4.Iuliu Hatieganu University, Faculty of Pharmacy, Cluj-Napoca, Romania -
MALPRACTICE AND PROFESSIONAL LIABILITY OF MEDICAL PERSONNEL
SILVIU PIȚURU, SIMONA VLĂDĂREANU*, SILVIU PĂUN, ANDREI NANU
“Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, Bucharest, Romania