Romanian Society of Pharmaceutical Sciences

Farmacia Journal 1/2024

Volume 72 | Number 1 | Year 2024

Download this issue’s covers, and announcements.

  1. THE CURRENT STATE OF THE PHARMACOTHERAPEUTIC APPROACH IN LICHEN PLANUS OF THE ORAL AND GENITAL MUCOSA

    1“Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021, Bucharest, Romania
    2Department of Obstetrics and Gynaecology, “Filantropia” Clinical Hospital, 11-13 Ion Mihalache Boulevard, 011171, Bucharest, Romania 3Department of Diabetes, Nutrition and Metabolic Diseases, “N.C. Paulescu” Nutrition and Metabolic Diseases, 5-7 Ion Movilă Street, 020475, Bucharest, Romania
    4Faculty of Dentistry, “Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021, Bucharest, Romania 5Department of Intensive Care, University Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021, Bucharest, Romania
    6Department of Clinical Laboratory, Food Safety, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, Bucharest 020945, Romania

    Download Full Article PDF

  2. BRYONIA ALBA L. – A PROSPECTIVE MEDICINAL PLANT OF THE CUCURBITACEAE FAMILY

    1Department of Applied Pharmaceutical Sciences, Faculty of Pharmacy, Isra University, Amman, Jordan 2Department of Pharmacognosy and Botany, Faculty of Pharmacy, Bogomolets National Medical University, Kyiv, Ukraine 3Department of Pharmacognosy and Nutriciology, National University of Pharmacy, Kharkiv, Ukraine
    4Faculty of Pharmacy, Amman Arab University, Jordan.
    5Truman State University, Columbia, USA

    Download Full Article PDF

  3. NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) AS REPURPOSED ANTICANCER DRUGS IN SKIN CANCER

    1Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041, Timișoara, Romania
    2Faculty of Dentistry, “Vasile Goldis” Western University of Arad, Liviu Rebreanu Street, no. 86, 310414, Arad, Romania
    3Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Revoluției 1989 Bvd, No. 9, 300041, Timișoara, Romania
    4Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041, Timișoara, Romania
    5Research Centre for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, 300041, No. 2, Timișoara, Romania
    6Faculty of Pharmacy, “Vasile Goldis” Western University of Arad, Revolutiei Bvd, no. 94, 310130, Arad, Romania

    Download Full Article PDF

  4. PHARMACOLOGICAL CONTAMINANTS IN AQUATIC ECOSYSTEMS

    1Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University of Galati, 47 Domnească Street, Galati, Romania
    2Pharmaceutical Science Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University of Galați, 47 Domnească Street, Galați, Romania
    3Clinical- Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University of Galați, 47 Domnească Street, Galați, Romania
    4Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu Street, Bucharest, Romania
    5“Carol Davila” University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu Street, Bucharest, Romania

    Download Full Article PDF

  5. INVESTIGATION OF THE EFFECTS OF METFORMIN ON THE miR- 21/PTEN/Akt PATHWAY IN HT-29 HUMAN COLORECTAL ADENOCARCINOMA CELL AND HUVEC CO-CULTURE

    1Deparment of Medical Pharmacology, Faculty of Medicine, University of Kastamonu, 37200, Kastamonu, Turkey
    2Deparment of Medical Pharmacology, Faculty of Medicine, University of Bilecik Şeyh Edebali, 11230, Bilecik, Turkey
    3Deparment of Pharmaceutical Toxicology, Faculty of Pharmacy,University of Istanbul, 34116, Istanbul, Turkey
    4Center of Bioanalytical Research and Molecular Design, Sechenov First Moscow State Medical University, 119991 Moscow, Russian Federation
    5Department of Pharmaceutical Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Traian Vuia 6, 020956, Bucharest, Romania
    6Department of Biochemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Traian Vuia 6, 020956, Bucharest, Romania
    7Department of Forensic Sciences and Toxicology, Faculty of Medicine, University of Crete, 71003, Heraklion, Greece

    Download Full Article PDF

  6. PILOT STUDY TO EVALUATE ADHERENCE TO TREATMENT USING THE MARS SCALE ON A SAMPLE OF ROMANIAN PATIENTS WITH CARDIOVASCULAR DISEASES

    1Department of Ethics and Social Sciences, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540142, Romania
    2Department of Psychiatry, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540142, Romania
    3Department VIII Neuroscience-Discipline of Psychiatry, “Victor Babeș” University of Medicine and Pharmacy of Timișoara, 300041, Romania
    4Department of Internal Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540142, Romania
    5Psychiatry Clinic 1, County Clinical Hospital Mureș, Târgu Mureș, Romania
    6Sanitary Management and Public Health,”Victor Babeș” University of Medicine and Pharmacy of Timișoara, 300041, Romania
    7Odorheiu Secuiesc Municipal Hospital, Santimbru street, 91, Odorheiu Secuiescu, Romania
    8Department of Forensic Medicine, Bioethics, Deontology and Medical Law,”Victor Babeș” University of Medicine and Pharmacy of Timișoara, 300041, Romania
    9Department of Pharmacology and Clinical Pharmacy,“George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540142, Romania
    10Surgical Department X,” Victor Babeș” University of Medicine and Pharmacy of Timișoara, 300041, Romania
    11Management Department, Faculty of Economics and Bussiness Administration, West University of Timișoara, 300115, Romania
    12Psychiatry Clinic 2, County Clinical Hospital Mureș, Târgu Mureș, Romania
    13Department of Forensic Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540142, Romania

    Download Full Article PDF

  7. THE DEVELOPMENT OF IN VITRO RELEASE METHODOLOGY FOR HIGH STRENGTH TOPICAL SEMISOLID FORMULATIONS OF ANTI-INFLAMMATORY DRUGS

    Centre for Drug Sciences, Biopharmaceutics Laboratory, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila Bucharest, 6 Traian Vuia Street, 020956, Bucharest, Romania

    Download Full Article PDF

  8. FLAVONOID PHYTOPROGESTIN COMPOUNDS AS PROGESTERONE RECEPTOR MODULATORS FOR ENDOMETRIUM RECEPTIVITY: A SYSTEMATIC SCREENING AND AN IN SILICO ANALYSIS

    1Department of Pharmacology, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, West Java, Indonesia
    2National Metabolomics Collaborative Research Center, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, West Java, Indonesia 3Department of Pharmacognosy, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, West Java, Indonesia
    4Computational Biology and Bioinformatics Laboratory, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, West Java, Indonesia 5NARA Institute of Science and Technology, Japan
    6Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Malaya, 50603 Kuala Lumpur, Malaysia

    Download Full Article PDF

  9. IN VITRO MULLEIN OIL INVESTIGATIONS AND IN VIVO EFFECTS OF MULLEIN OIL CREAM ON HUMAN SKIN PHYSIOLOGY

    1Department of Pharmacy, Faculty of Medicine, University of Niš, Blv. Zorana Đinđića 81, Niš, Serbia
    2Department of Biology and Ecology, Faculty of Sciences and Mathematics, University of Niš, Višegradska 33, Niš, Serbia

    Download Full Article PDF

  10. PHARMACOLOGICAL EVALUATION OF RHODIOLA ROSEA L. EXTRACT FROM THE KAZAKH ECOSYSTEM: IMPLICATIONS FOR OBESITY MANAGEMENT IN MALE RATS

    1Al-Farabi Kazakh National University, Al-Farabi Avenue, 71/19, 050060, Almaty, Kazakhstan
    2“Astana Botanical Garden” Branch of the Republican State Enterprise on the Right of Economic Management “Institute of Botany and Phytoinroduction”, Orynbor 16, 010016, Astana, Kazakhstan
    3Astana International University, Qabanbay Batyr Ave 8, 020000, Astana, Kazakhstan
    4Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia
    5Department of Biology and Ecology, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 2, 21000 Novi Sad, Serbia
    6Central Asian Centre for Development Studies, New Uzbekistan University, 54 Mustaqillik Avenue, Tashkent, 100007, Uzbekistan 7Department of Education and Training Management, Tashkent International University of Education, Imam Bukhari Street, Tuzel-2 block, Tashkent, 100207, Uzbekistan
    8Institute of Botany, Academy of Sciences of Republic of Uzbekistan, 32 Durmon Yuli, Tashkent 100125, Uzbekistan
    9Institute of Genetic and Physiology, prospect Al-Farabi, 93, Bostandyk district, 050060/A15E3K2, Almaty, Kazakhstan
    10Asfendiyarov Kazakh National Medical University, Tole by 94, 050012, Almaty, Kazakhstan

    Download Full Article PDF

  11. ADOPTION OF REMIFENTANIL COMBINED WITH PROPOFOL IN GENERAL ANESTHESIA SURGERY: META-ANALYSIS

    Department of Anesthesiology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai,317000, Zhejiang, China

    Download Full Article PDF

  12. INNOVATIVE TREATMENT AGAINST HUMAN PERIODONTITIS AND PERIIMPLANTITIS – IN VITRO STUDY

    1University of Agronomic Sciences and Veterinary Medicine Bucharest, Faculty of Veterinary Medicine, Splaiul Independenței 105, 050097, Bucharest, Romania
    2„Cantacuzino” National Medical Military Institute for Research and Development, Splaiul Independenței 103, 050096, Bucharest, Romania
    3 Institute for Diagnosis and Animal Health, 63 Dr. Staicovici Str., 050557, Bucharest, Romania

    Download Full Article PDF

  13. TYROSINE AMMONIA-LYASE ACTIVITY OF SEVERAL AROMATIC PLANTS FROM ALGERIAN SAHARA

    1University of Kasdi Merbah Ouargla, Faculty Natural and Life Sciences, Lab. Biogeochemistry of Desert Environments, Algeria
    2University of Hamma Lakhdar El Oued, Faculty Natural and Life Sciences, Algeria
    3University of Kasdi Merbah Ouargla, Faculty Applied Science, Lab. Biogeochemistry of Desert Environments., Algeria

    Download Full Article PDF

  14. POSSIBLE PROTECTIVE EFFECT OF NICARDIPINE ON ANIT INDUCE CHOLESTASIS IN RAT

    1Ministry Of Health And Environment, Alnuman Teaching Hospital, Baghdad, Iraq
    2Department of Pharmacology and Toxicology, College of Pharmacy, University of Baghdad, Baghdad, Iraq

    Download Full Article PDF

  15. 1H – NMR SPECTROSCOPY AND MULTIVARIATE ANALYSIS APPLICATION ON IDENTIFYING SYNTHETIC DRUGS IN ADULTERATED PAIN RELIEVER HERBAL MEDICINE

    1Doctoral Program in Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara, Yogyakarta, 55281, Indonesia 2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara, Yogyakarta, 55281, Indonesia 3Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia
    4Institute of Halal Industry and System (IHIS), Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia

    Download Full Article PDF

  16. PLASMA NICOTINE/COTININE LEVELS AS BIOMARKER OF ACTIVE SMOKING IN PATIENTS WITH PSYCHIATRIC DISORDERS

    1“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Bucharest, Romania
    2“Grigore Alexandrescu” Emergency Clinical Hospital for Children, Pediatric Clinic 2, Ward ATI -Toxicology, Bucharest, Romania
    3“Ovidius” University of Constanța, Department of Drug Analysis, Biopharmacy and Biological Medicines,Constanța, Romania
    4“Dunărea de Jos” University of Galați, Faculty of Medicine and Pharmacy, Galaţi, Romania
    5University of Crete, Faculty of Medicine, Department of Forensic Sciences and Toxicology, Heraklion, Greece

    Download Full Article PDF

  17. DEVELOPMENT AND VALIDATION OF AN HPTLC METHOD FOR BAKUCHIOL QUANTIFICATION IN PSORALEA CORYLIFOLIA SEEDS USING CENTRAL COMPOSITE DESIGN

    1Department of Natural Products & Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia
    2School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi-62, India
    3Department of Pharmacy, Mohammed Al-Mana College for Medical Sciences, Safaa, Dammam 34222, Saudi Arabia
    4Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
    5Department of Plant Resources and Environment, Jeju National University, 63234, Republic of Korea
    6Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia

    Download Full Article PDF

  18. PHYTOCHEMICAL SCREENING AND CYTOTOXIC EVALUATION OF SALVIA GREGGII EXTRACTS: AN IN VITRO AND IN SILICO STUDY

    1Department of Pharmaceutical Sciences, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, 11733, Amman, Jordan
    2Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmacy, Applied Science Private University, 11931, Amman, Jordan
    3Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, 11931, Amman, Jordan
    4Department of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, 11942 Amman, Jordan

    Download Full Article PDF

  19. BUFFERED AND NON-BUFFERED 4% ARTICAINE (1:100,000 EPINEPHRINE): CLINICALLY AND LABORATORY RESEARCH

    1Department of Oral surgery, Dental Faculty, Medical University of Plovdiv, Bulgaria
    2Department of Bioorganic chemistry, Faculty of Pharmacy, Medical University of Plovdiv, Bulgaria

    Download Full Article PDF

  20. SINGLE-CENTRE REAL-LIFE EXPERIENCE ON THE USE OF THROMBOPOIETIN RECEPTOR AGONIST (TPO-RA) FOR THE MANAGEMENT OF IMMUNE THROMBOCYTOPENIA IN CHILDREN

    1“Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania
    2Department of Pediatric Hematology and Oncology, Fundeni Clinical Institute, 022328 Bucharest, Romania
    3Department of Hematology, Coltea Clinical Hospital, 30171, Bucharest, Romania
    4Department of Intensive Care, University Emergency Hospital, 700111, Bucharest, Romania

    Download Full Article PDF

  21. EFFECT OF HYPEROSIDE ON KLOTHO PROTEIN IN RATS WITH CHRONIC RENAL FAILURE

    1Department of Nephrology, The Fourth Hospital of Harbin Medical University, Harbin, 150001, China
    2Department of Medical Function, Mudanjiang Medical University, Mudanjiang, 157011, China
    3Department of Pharmacology, Mudanjiang Medical University, Mudanjiang, 157011, China
    4Stem Cell Institute, Mudanjiang Medical University, Mudanjiang, 157011, China;
    5Department of Histology and Embryology, Mudanjiang Medical University, Mudanjiang, 157011, China
    6Clinical Skills Centre of The First Clinical College, Mudanjiang Medical University, Mudanjiang, Heilongjiang, 157011, China

    Download Full Article PDF

  22. DESIGN AND EVALUATION OF PROPOLIS-HPC/PVP ELECTROSPUN NANOFIBERS FOR POSSIBLE CUTANEOUS APPLICATIONS

    1Department of Pharmaceutical Technology, Hamidiye Faculty of Pharmacy, University of Health Sciences, Istanbul, Türkiye
    2Türkiye Biotechnology Institute, Health Institutes of Türkiye (TUSEB), Istanbul, Türkiye
    3Department of Pharmaceutical Technology, Faculty of Pharmacy, Sivas Cumhuriyet University, Sivas, Türkiye
    4Department of Preclinical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, Bihor, Romania
    5Department of Gastronomy and Culinary Arts, School of Tourism and Hotel Management, Sivas Cumhuriyet University, Sivas, Türkiye 6Department of Pharmacognosy, Faculty of Pharmacy, Bezmialem Vakıf University, Istanbul, Türkiye
    7Institute of Health Sciences, Bezmialem Vakıf University, Department of Pharmacognosy and Natural Product Chemistry, Istanbul, Türkiye. 8Phytotheraphy Research Center, Bezmialem Vakıf University, Istanbul, Türkiye
    9Department of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, Istanbul, Türkiye 10Department of Food Technology, Experimental Medicine Research and Application Centre, University of Health Sciences, Istanbul, Türkiye

    Download Full Article PDF

  23. NEPHROPROTECTIVE EFFECTS OF ETHYL ACETATE FRACTION FROM ARTOCARPUS ALTILIS AND A. HETEROPHYLLUS LEAVES ON GENTAMICIN-PIROXICAM NEPHROTOXICITY IN RATS

    1Department of Pharmacy, Universitas Sriwijaya, Jl. Raya Palembang-Prabumulih Km.32, Indralaya, 30662, South Sumatera, Indonesia 2Department of Chemistry, Universitas Sriwijaya, Jl. Raya Palembang-Prabumulih Km.32, Indralaya, 30662, South Sumatera, Indonesia 3Department of Biology, Universitas Sriwijaya, Jl. Raya Palembang-Prabumulih Km.32, Indralaya, 30662, South Sumatera, Indonesia

    Download Full Article PDF

  24. POSSIBLE PROTECTIVE ANTICANCER EFFECT OF ETHYL ACETATE FRACTION OF IRAQI HIBISCUS TILIACEUS L. LEAVES EXTRACT ON DIETHYLNITROSAMINE-INDUCED HEPATOCARCINOGENESIS IN MALE RATS

    1Medicolegal Directorate, Ministry of Health and Environment, Baghdad-Iraq.
    2Department of Pharmacology and Toxicology, College of Pharmacy, University of Baghdad, Baghdad, Iraq.

    Download Full Article PDF

  25. EXPERIMENTAL EVALUATION OF THE INFLUENCE OF AMIODARONE ON WOUND HEALING

    1Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 020021, Bucharest, Romania
    2Department of Medical Informatics and Biostatistics, “Carol Davila” University of Medicine and Pharmacy, 020021, Bucharest, Romania
    3“Carol Davila” University of Medicine and Pharmacy, 020021, Bucharest, Romania

    Download Full Article PDF