Farmacia Journal 4/2019
Volume 67 | Number 4 | Year 2019
Download this issue’s covers and announcements.
-
CURRENT VIEW ON VITAMIN K2 ROLE IN DISEASES BASED ON CLINICAL TRIALS
PIOTR JAKUBOWSKI 1*, ŁUKASZ SMYK 1, ŁUKASZ PUCHAŁA 2, JOANNA BIAŁKOWSKA 3
1.Department of Pharmacology and Toxicology, School of Medicine, University of Warmia and Mazury in Olsztyn, 30 Warszawska Street, 11-041 Olsztyn, Poland
2.Department of Medical Biology, Faculty of Health Sciences, University of Warmia and Mazury in Olsztyn, 14C Żołnierska Street, 10-900 Olsztyn, Poland
3.Department of Public Health, Faculty of Health Sciences, University of Warmia and Mazury in Olsztyn, 14C Żołnierska Street, 10-900 Olsztyn, Poland -
INSIGHTS INTO CHRONONUTRITION: THE INNERMOST INTERPLAY AMONGST NUTRITION, METABOLISM AND THE CIRCADIAN CLOCK, IN THE CONTEXT OF EPIGENETIC REPROGRAMMING
CRISTINA MANUELA DRĂGOI 1#, ELENA MOROŞAN 1#, ION-BOGDAN DUMITRESCU 1#, ALINA CRENGUŢA NICOLAE 1*, ANDREEA LETIŢIA ARSENE 1#, DOINA DRĂGĂNESCU 1, DUMITRU LUPULIASA 1, ANA CORINA IONIŢĂ 1, ANCA PANTEA STOIAN 1, CAMELIA NICOLAE 1#, MANFREDI RIZZO 2,3, MAGDALENA MITITELU 1
1“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2Biomedical Department of Internal Medicine and Medical Specialties School of Medicine, University of Palermo, Palermo, Italy
3Division of Endocrinology, Diabetes and Metabolism University of South Carolina School of Medicine Columbia, South Carolina, United States of America -
POTENTIAL DRUG-DRUG INTERACTIONS AND STRATEGIES FOR THEIR DETECTION AND PREVENTION
MUHAMMAD KASHIF RIAZ 1,2*
1.University College of Pharmacy, University of the Punjab, Lahore, Pakistan
2.Pharmaceutics Section, Teaching and Research Division, School of Chinese Medicine, Hong Kong Baptist University, 7 Baptist University Road, Kowloon Tong, Hong Kong -
PLGA-GENTAMICIN BIOCOMPOSITE MATERIALS WITH POTENTIAL ANTIMICROBIAL APPLICATIONS IN ORTHOPEDICS
MARIA-VIORICA CIOCÎLTEU 1, PAULINA PODGOREANU 2*, CRISTINA DELCARU 2, MARIANA-CARMEN CHIFIRIUC 2, COSTEL VALENTIN MANDA 1, ANDREI BIŢĂ 1, MARIANA POPESCU 1, EMILIA AMZOIU 1, OCTAVIAN CROITORU 1, CORALIA BLEOTU 3, MARINELA BOSTAN 3, JOHNY NEAMŢU 1
1.Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Petru Rares Street, 200638, Craiova, Romania
2.Research Institute of the University of Bucharest (ICUB), Earth, Environmental and Life Sciences Division, University of Bucharest, 36-46 M. Kogălniceanu Boulevard, 050107, Bucharest, Romania
3.Center of Immunology, “Ștefan S. Nicolau” Institute of Virology, 285 Mihai Bravu Road, 030304, Bucharest, Romania -
THERMAL PROCESSING EFFECTS ON THE MICROBIOLOGICAL, PHYSICOCHEMICAL, MINERAL, AND NUTRACEUTICAL PROPERTIES OF A ROASTED PURPLE MAIZE BEVERAGE
PABLO A. RODRÍGUEZ-SALINAS 1, DOLORES MUY-RANGEL 2, VANIA URÍAS-ORONA 3, FRANCISCO ZAVALA-GARCÍA 1, ÁNGELA SUÁREZ-JACOBO 4, JOSÉ B. HEREDIA 2, WERNER RUBIO-CARRASCO 2, GUILLERMO NIÑO-MEDINA 1*
1Universidad Autónoma de Nuevo León, Facultad de Agronomía, Laboratorio de Química y Bioquímica, Francisco Villa S/N, Col. Ex Hacienda El Canadá, C.P. 66050. General Escobedo, Nuevo León, México
2Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C., Coordinación Culiacán. Carretera Culiacán a El Dorado km 5.5, C.P. 80110. Col. Campo el Diez, Culiacán, Sinaloa, México
3Universidad Autónoma de Nuevo León, Facultad de Salud Pública y Nutrición, Laboratorio de Química de los Alimentos. Av. Dr. Eduardo Aguirre Pequeño y Yuridia, Col. Mitras Centro, C.P. 64460. Monterrey, Nuevo León, México
4Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco (CIATEJ), A.C., Unidad Noreste. Parque de Investigación e Innovación Tecnológica (PIIT), C.P. 66629. Apodaca, Nuevo León, México -
EXPERIMENTAL PHARMACOLOGICAL RESEARCH REGARDING THE EFFECT OF SOME NEWLY SYNTHESIZED Β-PHENYLETHYL AMINES ON THE MODIFIED PARAMETERS OF THE LIPID METABOLISM
EMIL ȘTEFĂNESCU 1#, ELENA MOROȘAN 2#, HOREA GURGU 3#, ISABEL CRISTINA VIORICA GHIȚĂ 4#, ANCA ZANFIRESCU 1*, CRISTINA ELENA ZBÂRCEA 1, OVIDIU MUȘAT 5, SIMONA NEGREȘ 1
1.Pharmacology and Clinical Pharmacy Department, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
2.Clinical Laboratory and Food Hygiene Department, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
3.Pharmaceutical Chemistry Department, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
4.Pharmacology Department, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 8 Eroii Sanitari Street, 050474, Bucharest, Romania
5.Central Military Emergency Hospital,139 Calea Plevnei Street, 010825, Bucharest, Romania -
BIOACTIVE EXTRACTS FROM CULTIVATED AJUGA GENEVENSIS L. AND A. REPTANS L.: IN VITRO/IN VIVO PHARMACOLOGICAL EFFECTS
ANDREI FLORIN PĂDURARU 1, OANA CIOANCĂ 1*, CORNELIA MIRCEA 1, ADRIANA TRIFAN 1, ANA CLARA APROTOSOAIE 1, ANCA MIRON 1, ELVIRA GILLE 2, LUCIAN HRITCU 3, MONICA HĂNCIANU 1
1.Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania
2.National Institute of R&D for Biological Sciences, “Stejarul” Biological Research Centre, Piatra Neamț, Romania
3.Department of Biology, Faculty of Biology, “Alexandru Ioan Cuza” University, Iași, Romania -
ANTIFUNGAL ACTIVITY AND CHEMICAL COMPOSITION OF ENDOPHYTIC FUNGUS PHANEROCHAETE SP. MFLUCC16-0609
SARUNPRON KHRUENGSAI 1, CHUTIMA TANAPICHATSAKUL 1, SUCHAWADEE INSAWANG 1, SINANG HONGSANAN 2,3, PATCHAREE PRIPDEEVECH 1,4*
1.School of Science, Mae Fah Luang University, Chiang Rai 57100, Thailand
2.Center of Excellence in Fungal Research, Mae Fah Luang University, Chiang Rai 57100, Thailand
3.Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China
4.Center of Chemical Innovation for Sustainability (CIS), Mae Fah Luang University, Chiang Rai, Thailand -
INFLUENCE OF FLUVOXAMINE ON CARVEDILOL'S PHARMACOKINETICS IN RATS
MARIA BIANCA ABRUDAN 1, DANA MARIA MUNTEAN 1*, LAURIAN VLASE 1, ANA-MARIA GHELDIU 1, CRISTIAN BERCE 2, LAURENȚIU STOICESCU 3, MARIA ADRIANA NEAG 4
1.Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș, Cluj-Napoca 400012, Romania
2.Centre for Experimental Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy, 6 Louis Pasteur, Cluj-Napoca 400349, Romania
3.Department of Cardiology, Vth Medical Clinic, Clinical Municipal Hospital, “Iuliu Hațieganu” University of Medicine and Pharmacy, Faculty of Medicine, 11 Tăbăcarilor, Cluj-Napoca 400139, Romania
4.Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș, Cluj-Napoca 400012, Romania -
ELECTROPHORESIS AND RAMAN SPECTROSCOPY CHARACTERIZATION OF INTEGRITY AND SECONDARY STRUCTURE OF p-SCN-Bn-DTPA- AND p-SCN-Bn-1B4M-DTPACONJUGATED TRASTUZUMAB
MARIJA STERJOVA 1,2*, PREDRAG DŽODIĆ 2, PETRE MAKRESKI 3, JELENA ŽIVKOVIĆ 4, EMILIJA JANEVIK-IVANOVSKA 1
1.“Goce Delčev” University, Faculty of Medical Sciences, 10-А “Krste Misirkov” Street, 2000 Štip, Republic of Macedonia
2.University of Niš, Faculty of Medicine, Department of Pharmacy, 81dr Zoran Đindić Street, 18000 Niš, Serbia
3.Institute of Chemistry, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University, 1000 Skopje, Republic of Macedonia
4.University of Niš, Faculty of Medicine, Department of Chemistry, , 81dr Zoran Đindić Street, 18000 Niš, Serbia -
WATER STRUCTURING EFFECT OF METHANOL AND ETHANOL ON ION PAIRING OF SOME GUANIDIUM CONTAINIG PHARMACEUTICAL SUBSTANCES. ANALYTICAL APPLICATIONS
MARINELA FLOREA1, IOANA CLEMENTINA CONSTANTINESCU1*, ANGELA NEDELCU1, CLAUDIA-MARIA GUȚU2, MAHER ABDULRAZZAQ LUQMAN AL-HAKEEM3, LĂCRĂMIOARA POPA3
”Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
1.Department of Analytical Chemistry
2.Department of Toxicology
3.Department of Physical and Colloidal Chemistry -
THE HISTO-ANATOMICAL INVESTIGATION AND THE POLYPHENOLIC PROFILE OF ANTIOXIDANT COMPLEX ACTIVE INGREDIENTS FROM THREE VIOLA SPECIES
TÜNDE JURCA 1, ANNAMARIA PALLAG 1*, ELEONORA MARIAN 1, MARIANA EUGENIA MUREȘAN 1, ROXANA LIANA STAN 2, LAURA GRAȚIELA VICAȘ 1
1University of Oradea, Medicine and Pharmacy Faculty, Department of Pharmacy,29 Nicolae Jiga Str., 410028, Oradea, Romania
2Department of Pharmaceutical Biochemistry and Clinical Laboratory, Faculty of Pharmacy, University of Medicine and Pharmacy „Iuliu-Hațieganu” Cluj-Napoca, 400012, Romania -
PHENOLIC SUBSTANCE CONTENTS AND BIOLOGICAL ACTIVITIES OF VERBASCUM INSULARE BOISS. & HELDR. EXTRACTS
YUSUF ALAN 1*, NIMET YILMAZ 2
1.Faculty of Education, Department of Primary Education, Muş Alparslan University, 49250, Muş, Turkey
2.Institute of Science, Department of Biology, Muş Alparslan University, 49250, Muş, Turkey -
NEW EXPERIMENTAL DATA ON THE CENTRAL EFFECTS OF AN OLD ANALGESIC – PARACETAMOL
FLORIN BOGDAN EPUREANU 1#, HORIA PĂUNESCU 1*, ISABEL GHIȚĂ 1#, MIHNEA COSTESCU 1#, LAURENȚIU COMAN 2, ION FULGA 1, OANA ANDREIA COMAN 1
1.Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2.Department of Physiology, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania -
ASSESSMENT OF THE POTENTIAL ANTITUMOR EFFECTS OF GLINUS OPPOSITIFOLIUS (L.) AUG. DC. EXTRACTS
ALEXANDRU VASINCU 1, DANIELA-CARMEN ABABEI 1, ANCA MIRON 1*, MONICA NEAMŢU 1, IOANA-MIRELA VASINCU 1, CHRISTIANA CHARALAMBOUS 2, CHRISTIANA M. NEOPHYTOU 3, ANDREAS I. CONSTANTINOU 3
1.“Grigore T. Popa” University of Medicine and Pharmacy Iasi, Faculty of Pharmacy, 16 Universităţii Street, 700115, Iași, Romania
2.University of Nicosia, Medical School, 93 Agiou Nikolaou Street, Engomi 2408 Nicosia, Cyprus
3.University of Cyprus, Department of Biological Sciences, 75 Kallipoleos Street, 1678 Nicosia, Cyprus -
ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF BIOSYNTHESIZED SILVER NANOPARTICLES FROM ULMUS WALLICHIANA PLANCH. LEAF EXTRACT
ANSAR MEHMOOD 1*, SHAISTA SHABIR 1, SAJJAD HUSSAIN 1, KHAWAJA SHAFIQUE AHMAD 1, ABDUL HAMID 2
1.Department of Botany, University of the Poonch Rawalakot, 12350, Azad Kashmir, Pakistan
2.Department of Horticulture, University of the Poonch Rawalakot, 12350, Azad Kashmir, Pakistan -
PREPARATION AND IN VITRO EVALUATION OF FELODIPINELOADED POLY(ε-CAPROLACTONE) MICROSPHERES: QUALITY BY DESIGN APPROACH
MARCELA ACHIM 1, LUCIA RUXANDRA TEFAS 1*, RAREȘ IOVANOV 1, ANDREEA LOREDANA VONICA-GLIGOR 1,2, LUCIAN BARBU-TUDORAN 3, IOAN TOMUȚĂ 1
1.“Iuliu Hațieganu” University of Medicine and Pharmacy Cluj-Napoca, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, 41 V. Babeş Street, 400012 Cluj-Napoca, Romania
2.“Lucian Blaga” University, 2A L. Blaga Street, 550169 Sibiu, Romania
3.“Babeș-Bolyai” University, Faculty of Biology & Geology, Electron Microscopy Center, 5-7 Clinicilor Street, 400006 Cluj-Napoca, Romania -
IN VITRO EFFECTS OF SOME SYNTHESIZED AMINOACETANILIDE N’-SUBSTITUTED ON HUMAN LEUKOCYTES SEPARATED FROM PERIPHERAL BLOOD
ANA CORINA IONIȚĂ 1, MANUELA GHICA 2, ELENA MOROȘAN 1*, FLORICA NICOLESCU 3, MAGDALENA MITITELU 1
1.University of Medicine and Pharmacy “Carol Davila”, Faculty of Pharmacy, Department of Clinical Laboratory and Food Safety, 6 Traian Vuia Street, 020956, Bucharest, Romania
2.University of Medicine and Pharmacy “Carol Davila”, Faculty of Pharmacy, Department of Biostatistics, 6 Traian Vuia Street, 020956, Bucharest, Romania
3.University of Medicine and Pharmacy “Carol Davila”, Faculty of Pharmacy, Department of Toxicology, 6 Traian Vuia Street, 020956, Bucharest, Romania -
THERAPEUTIC EFFECTS OF ALOPERINE ON THE PULMONARY ARTERIAL HYPERTENSION
SHUANG LI 1, FUBO ZHOU 2, JIANJIANG DONG 3, QI DONG 1, HAIRONG LUAN 1, LI LI 1, YANKUN HAO 1*
1.Department of Medical Function, Mudanjiang Medical University, Mudanjiang 157011, People’s Republic of China
2.Department of Pharmacology, Mudanjiang Medical University, Mudanjiang 157011, People’s Republic of China
3.Department of Histology and Embryology, Mudanjiang Medical University, Mudanjiang 157011, People’s Republic of China -
CONTRIBUTIONS ON FORMULATION AND PRELIMINARY EVALUATION OF OCULAR COLLOIDAL SYSTEMS OF CHITOSAN AND POLOXAMER 407 WITH BUPIVACAINE HYDROCHLORIDE
TEODORA IRIMIA, GABRIELA CORNELIA MUŞAT *, RĂZVAN MIHAI PRISADA, MIHAELA VIOLETA GHICA, CRISTINA ELENA DINU-PÎRVU, VALENTINA ANUŢA, BRUNO ŞTEFAN VELESCU, LĂCRĂMIOARA POPA
“Carol Davila” University of Medicine and Pharmacy Bucharest, 37, Dionisie Lupu Street, 020021, Bucharest, Romania
-
DESIGN AND OPTIMIZATION OF FAST DISPERSIBLE FORMULATIONS OF MULTI STRENGTH MELOXICAM TABLETS USING RESPONSE SURFACE METHODOLOGY
HUMA ALI 1*, FARYA ZAFAR 2, SOHAIL KHAN 3, RIFFAT YASMEEN 4, RABIA BUSHRA 4, SABA AIJAZ BALOCH 3
1.Institute of Pharmaceutical Sciences, Jinnah Sindh Medical University, Karachi, Pakistan
2.Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan
3.Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan
4.DCOP, Faculty of Pharmacy, Dow University of Health Sciences, Karachi, Pakistan -
ANTIOXIDANT EFFECTS ON VASCULAR ENDOTHELIAL CELLS INDUCED BY ACTIVE COMPONENTS OF PUNICA GRANATUM AND AMARANTHUS SP. EXTRACTS
CRISTINA DIȚESCU 1, NARCISA BĂBEANU 1, LAURA OLARIU 2,3, BRÎNDUȘA DUMITRIU 2*, RALUCA PAPACOCEA 4, OVIDIU POPA 1, BRUNO ȘTEFAN VELESCU 4
1.University of Agronomical Sciences and Veterinary Medicine of Bucharest, 59 Mărăști Boulevard, 011464, Bucharest, Romania
2.S.C. Biotehnos S.A., 3-5 Gorunului Street, 075100, Otopeni, Ilfov, Romania
3.Academy of Romanian Scientists, 54 Splaiul Independenței Street, 050094, Bucharest, Romania
4.“Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021, Bucharest, Romania -
QbD BASED CONTROL STRATEGY OF LORATADINE NANOSUSPENSIONS AND DRY NANOPARTICLES STABILIZED BY SOLUPLUS®
AREEN ALSHWEIAT, RITA AMBRUS *, GÁBOR KATONA, ILDIKÓ CSÓKA
Faculty of Pharmacy, Interdisciplinary Excellence Centre, Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Szeged, Hungary
-
ETHICAL ASPECTS OF FOOD SUPPLEMENTS IN EU AND ROMANIA
EMILIA STANCU 1, ADRIANA-ELENA TĂEREL 1*, VALENTINA SOROCEANU 1, CRISTINA RAIS 1, MANUELA GHICA 2
“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
1.Department of Pharmaceutical Management and Marketing
2.Department of Biostatistics -
EVALUATION OF REIMBURSEMENT POLICY ABOUT ANTI-TNF AGENTS IN TURKEY
EMRAH BILGENER *
Nursing Department, Faculty of Health Sciences, Hitit University, Çorum, Turkey