Romanian Society of Pharmaceutical Sciences

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POTENTIAL DRUG-DRUG INTERACTIONS AND STRATEGIES FOR THEIR DETECTION AND PREVENTION

MUHAMMAD KASHIF RIAZ 1,2*

1.University College of Pharmacy, University of the Punjab, Lahore, Pakistan
2.Pharmaceutics Section, Teaching and Research Division, School of Chinese Medicine, Hong Kong Baptist University, 7 Baptist University Road, Kowloon Tong, Hong Kong

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Drugs are often used in combination to achieve a desired therapeutic goal. The concomitant use of drugs may lead to drugdrug interactions (DDIs), which may cause undesired effects in patients. Healthcare professionals should be provided with necessary information about potential drug-drug interaction (pDDIs). The article reviews recent work done on pDDIs, especially in patients with different age groups and co-existing disease conditions. The article also focuses on strategies for the detection of pDDIs and provides information about utilization of these strategies for their prevention.