Romanian Society of Pharmaceutical Sciences

Farmacia Journal 5/2024

Volume 72 | Number 5 | Year 2024

Download this issue’s covers, and announcements.

  1. CARDIAC SURVEILLANCE IN ONCOLOGY: A REVIEW OF CIRCULATING BIOMARKERS AND DIAGNOSIS METHODS IN CHEMOTHERAPY-INDUCED CARDIOTOXICITY

    1 “Babeș-Bolyai” University, Faculty of Biology and Geology, Doctoral School of Integrative Biology, 44 Republicii Street, Cluj-Napoca, Romania
    2 “Babeș-Bolyai” University, Faculty of Biology and Geology, Department of Molecular Biology and Biotechnology, 44 Republicii Street, Cluj-Napoca, Romania
    3 “Babeș-Bolyai” University, Faculty of Biology and Geology, Centre for Systems Biology, Biodiversity and Bioresources (3B), 44 Republicii Street, Cluj-Napoca, Romania

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  2. ADVANCES OF CO-PROCESSED EXCIPIENTS: APPLICABILITY AND FUNCTIONAL CHARACTERISTIC IMPROVEMENTS

    Laboratory of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Indonesia, Depok, West
    Java, 16424, Indonesia

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  3. DEVELOPMENT AND CHARACTERIZATION OF MEFENAMIC ACID EUTECTOGELS FOR CONTROLLED DRUG DELIVERY

    1 Department of Physical and Colloidal Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
    2 Innovative Therapeutic Structures Research and Development Centre (InnoTher), “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania

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  4. EUGENOL – A NATURAL ALTERNATIVE IN DENTISTRY: AN IN VITRO AND IN OVO BIOSAFETY ASSESSMENT

    1 Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041 Timișoara, Romania
    2 Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041 Timișoara, Romania
    3 Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041 Timișoara, Romania

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  5. MECHANISM OF CELASTRUS ORBICULATUS EXTRACT INHIBITING THE INVASION AND METASTASIS OF GASTRIC CANCER CELLS THROUGH RAC1/LIMK1/COFILIN 1 PATHWAY

    1 Department of Academic Theory Research, Mudanjiang Medical University, Mudanjiang, 157011, Heilongjiang, China
    2 Department of Pathology, Mudanjiang Tumour Hospital, Mudanjiang, 157011, Heilongjiang, China
    3 Department of Gastroenterology, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang, 157011, Heilongjiang, China
    4 Department of General Surgery, Affiliated Hongqi Hospital of Mudanjiang Medical University, Mudanjiang, 157011, Heilongjiang, China

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  6. CONTROLLED RELEASE AND ANTIBACTERIAL EFFICACY OF TETRACYCLINE AND METRONIDAZOLE LOADED PCL NANOWIRES ON ZIRCONIUM SUBSTRATE

    1 Department of General Chemistry, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology POLITEHNICA Bucharest, 313 Splaiul Independenței, 060042, Bucharest, Romania
    2 Department of Physical and Colloidal Chemistry, “Carol Davila” University of Medicine and Pharmacy, 020956, Bucharest, Romania
    3 Buftea Obstetrics and Gynaecology Hospital, 070000, Ilfov, Romania
    4 Department of Pharmaceutical Physics and Informatics, “Carol Davila” University of Medicine and Pharmacy, 020956, Bucharest, Romania
    5 Academy of Romanian Scientists, 3 Ilfov Street, 050044, Bucharest, Romania

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  7. THE STATE OF THE MYOCARDIAL NITROOXIDERGIC SYSTEM DURING MODELLING OF DOXORUBICIN-INDUCED CHRONIC HEART FAILURE AND THE ADMINISTRATION OF ΒETA-BLOCKERS OF VARIOUS GENERATIONS

    Zaporizhzhia State Medical and Pharmaceutical University, Zaporizhzhia, Ukraine

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  8. PHYTOCHEMICAL ANALYSIS OF THE BIOACTIVE PROPERTIES OF GREEN COFFEE BEANS OF ARABICA AND ROBUSTA VARIETIES

    1 “Titu Maiorescu” University of Bucharest, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 16 Gh. Șincai Boulevard, District 4, Bucharest, Romania
    2 “Ovidius” University of Constanța, Department of Chemistry and Chemical Engineering, 124 Mamaia Boulevard, Constanța, Romania
    3 National Institute of Research for Electrochemistry and Condensed Matter, Laboratory of Electrochemistry and Condensed Matter, 202 Splaiul Independentei Street, 060021, Bucharest, Romania
    4 ”Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Clinical Laboratory and Food Hygiene Department, 3-6 Traian Vuia Street, 020956, Bucharest, Romania

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  9. LEMON OIL NANO EMULSION NEW FORMULATION FOR TOPICAL APPLICATION AND IN VITRO EVALUATION FOR BIOLOGICAL ACTIVITY

    1 Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia
    2 Department of Pharmaceutics, HIMT College of Pharmacy, Greater Noida, Uttar Pradesh, India
    3 Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Saudi Arabia
    4 Pharmacy Practice Research Unit, College of Pharmacy, Jazan University, Jazan, Saudi Arabia
    5 Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia
    6 Department of Pharmacology and Toxicology, College of Pharmacy, Jazan University, Saudi Arabia

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  10. A QUALITY-BY-DESIGN APPROACH FOR OPTIMISATION OF DOCETAXEL TRANSFEROSOMAL FORMULATIONS

    1 Department of Physical and Colloidal Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 020956, Bucharest, Romania
    2 Innovative Therapeutic Structures Research and Development Centre (InnoTher), “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
    3 National Institute for Research & Development in Chemistry and Petrochemistry – ICECHIM Bucharest, 202 Spl. Independenței, 060021, Bucharest, Romania
    4 Faculty of Chemical Engineering and Biotechnology, “Politehnica” National University of Science and Technology Bucharest, 1-7 Gh. Polizu Street, 011061, Bucharest, Romania

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  11. OLANZAPINE AND FLUOROQUINOLONES ANTIBIOTICS: A NON CLINICAL STUDY OF DRUG-DRUG INTERACTIONS DUE TO CYP1A2 INHIBITION

    1 Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
    2 Department of Pharmaceutical Botany, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

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  12. CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OIL OF HELICHRYSUM ITALICUM FROM MEDITERRANEAN COAST

    1 University of Montenegro, Faculty of Medicine, Krusevac bb, 81 000 Podgorica, Montenegro
    2 Center for Eco-Toxicological Research Podgorica, Bulevar Šarla De Gola 2, 81000 Podgorica, Montenegro
    3 Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia

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  13. NON-DESTRUCTIVE ANALYSIS OF BARIUM SULPHATE TABLETS BY NEAR-INFRARED SPECTROSCOPY

    1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayuthaya Road, Rajathevi, Bangkok 10400, Thailand
    2 Department of Diagnostic Radiology, Siriraj hospital, Mahidol University, Bangkok, Thailand 3Department of Manufacturing Pharmacy, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayuthaya Road, Rajathevi, Bangkok 10400, Thailand

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  14. COMPARATIVE MORPHO-ANATOMICAL STUDIES FOR TWO ASIMINA TRILOBA VARIETIES, PRIMA 1216 AND ITHACA

    1 ”Dăbuleni” Research-Development Station for Plant Cultivation on Sandy Soil, 217 Petre Banita Street, 207170, Dolj, Romania
    2 Department of Pharmaceutical Botany and Cell Biology “Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, 020945, Bucharest, Romania
    3 National Institute for Research and Development in Microtechnologies, Erou Iancu Nicolae Street, 077190, Voluntari, Ilfov, Romania
    4 Department of Pharmaceutical Technology and Biopharmacy “Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, 020945, Bucharest, Romania
    5 Department of Botany and Microbiology, Faculty of Biology, University of Bucharest, 1-3 Aleea Portocalelor Street, 060101, Bucharest, Romania
    6 Botanical Garden “D. Brândza”, University of Bucharest, 32 Cotroceni Street, 060114, Bucharest, Romania
    7 Department of Pharmacognosy and Phytotherapy, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2 Petru Rareş Street, 200349, Craiova, Dolj, Romania
    8 Department of Pharmacognosy, Phytochemistry and Phytotherapy, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020945, Bucharest, Romania
    9 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020945, Bucharest, Romania
    10 Department of Clinical Laboratory and Food Safety, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020945, Bucharest, Romania
    11 Department of Pharmaceutical Botany, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2 Petru Rareş Street, 200349, Craiova, Dolj, Romania

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  15. HAIR AND SERUM TRACE ELEMENT AND MINERAL LEVELS IN PATIENTS WITH AGE-RELATED CATARACT

    1 Laboratory of Ecobiomonitoring and Quality Control, Yaroslavl State University, Yaroslavl 150003, Russian Federation
    2 Center for Bioelementology and Human Ecology, IM Sechenov First Moscow State Medical University (Sechenov University), Moscow 119146, Russian Federation
    3 Laboratory of Toxicology, Medical School, University of Crete, Heraklion 700 13, Greece
    4I nstitute of Bioelementology, Orenburg State University, Orenburg 460000, Russian Federation
    5 Orenburg Central District Hospital, Orenburg 460000, Russian Federation
    6 Department of Preventive Medicine and Public Health Laboratory Science, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China

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  16. IN VITRO ASSESSMENT OF 17ß-ETHINYLESTRADIOL AND LEVONORGESTREL ON BREAST CANCER MCF-7 AND MDA-MB 231 CELL LINES

    1 Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041 Timișoara, Romania
    2 Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041 Timișoara, Romania
    3 Research Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041 Timișoara, Romania
    4 Faculty of Pharmacy, “Vasile Goldiș” Western University of Arad, Revolutiei Bvd. 94, 310130 Arad, Romania

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  17. ENHANCED CYTOTOXICITY OF IRINOTECAN ADSORBED ON MESOSTRUCTURED ALUMINOSILICATE MATRICES

    1 Biophysics and Cellular Biotechnology Dept., “Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania
    2 Excellence Centre for Research in Biophysics and Cellular Biotechnology, “Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania
    3 Faculty of Chemical Engineering and Biotechnologies, National University for Science and Technology Politehnica of Bucharest, 011061, Bucharest, Romania
    4 “Ilie Murgulescu” Institute of Physical Chemistry, Romanian Academy, 060021, Bucharest, Romania
    5 National Institute for Chemical - Pharmaceutical Research and Development - ICCF, 031299, Bucharest, Romania
    6 Microbiology III Dept., “Carol Davila” University of Medicine and Pharmacy, 050098, Bucharest, Romania

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  18. THERAPEUTIC OUTCOME OF SODIUM HYALURONATE EYE DROPS COMBINED WITH RECOMBINANT EPIDERMAL GROWTH FACTOR DERIVATIVE EYE DROPS ON POSTOPERATIVE XEROPHTHALMIA

    Department of Ophthalmology, General Hospital of Hunan Medical University, Huaihua, 418000, Hunan, China

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  19. VINORELBINE-LOADED pH-SENSITIVE LIPOSOMES: DEVELOPMENT, CHARACTERIZATION AND IN VITRO EVALUATION

    1 Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012, Cluj-Napoca, Romania
    2 Research Centre for Functional Genomics, Biomedicine and Translational Medicine, University of Medicine and Pharmacy “Iuliu Hațieganu”, 23 Gheorghe Marinescu Street, 400337, Cluj-Napoca, Romania

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  20. IDENTIFICATION OF PHARMACOLOGICALLY RELEVANT MUTATIONS IN ENDOMETRIAL CANCER BY WHOLE-EXOME SEQUENCING OF FFPE TUMOUR SAMPLES

    1 Department of Obstetrics and Gynaecology, “Carol Davila” University of Medicine and Pharmacy, 38-52 Gh. Polizu Street, 011062, Bucharest, Romania
    2 Department of Obstetrics and Gynaecology, “Alessandrescu-Rusescu” National Institute of Mother and Child Health, 38-52 Gh. Polizu Street, 011062, Bucharest, Romania
    3 Department of Pathology, “Carol Davila” University of Medicine and Pharmacy, 38-52 Gh. Polizu Street, 011062, Bucharest, Romania
    4 Department of Pathology, “Alessandrescu-Rusescu” National Institute of Mother and Child Health, 38-52 Gh. Polizu Street, 011062, Bucharest, Romania
    5 Department of Oncological Surgery, “Carol Davila” University of Medicine and Pharmacy, 252 Fundeni Road, 022328, Bucharest, Romania
    6 Department of Oncological Surgery, “Alexandru Trestioreanu” Oncology Institute, 252 Fundeni Road, 022328, Bucharest, Romania
    7 Department of Obstetrics and Gynaecology, “Filantropia” Obstetrics and Gynaecology Clinical Hospital, 11-13 Ion Mihalache Boulevard., 011132, Bucharest, Romania

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  21. GC-MS BASED CHARACTERIZATION, ANTIMICROBIAL ACTIVITY OF GARLIC CO2 SUBCRITICAL EXTRACT (ALLIUM SATIVUM)

    1 Higher School of Medicine, “al-Farabi Kazakh National University”, Almaty, Kazakhstan
    2 JSC Scientific Centre for Anti-infectious Drugs, Almaty, Kazakhstan
    3 School of Pharmacy, “Asfendiyarov Kazakh” National Medical University, Almaty, Kazakhstan
    4 “Astana” Medical University, MUA, Nur-Sultan, Kazakhstan
    5 University of Health Sciences, Department of Medicinal and Aromatic Plants, 34668, Üsküdar, Istanbul, Türkiye
    6 School of Agriculture, Food and Ecosystem Sciences, Faculty of Science, Food Science and Nutrition, The University of Melbourne, Melbourne, Australia
    7 JSC Scientific Centre for Anti-infectious Drugs, Head of Quality Department, Almaty, Kazakhstan

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  22. IMPROVING DIAGNOSTIC ACCURACY IN DIMPYLATE POISONING: A COMPARATIVE STUDY OF CHOLINESTERASE ASSAYS

    1 “Cantacuzino” National Institute for Medical-Military Research and Development, Bucharest, Romania
    2 Doctoral Schools in the Faculty of Chemical Engineering and Biotechnologies, “Politehnica” University of Bucharest, Bucharest, Romania
    3 “Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Bucharest, Romania

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  23. THE EFFECT OF SACUBITRIL/VALSARTAN COMBINED WITH METOPROLOL SUCCINATE SUSTAINED-RELEASE TABLET ON CARDIAC FUNCTION IN PATIENTS WITH CORONARY HEART DISEASE AND HEART FAILURE

    1 Cardiac function Room, The Second Affiliated Hospital of Dalian Medical University, Dalian, 116023, China
    2 Department of Pharmacy, Tropical Agricultural Technology College, Hainan Vocational University, Haikou, 570216, China
    3 Department of Cardiothoracic Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou, 570102, China
    4 Department of Cardiology, Sanya Central Hospital (Hainan Third People’s Hospital), Sanya, 572029, China

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  24. ANTI-INFLAMMATORY EFFECTS OF LOCALLY VERSUS SYSTEMIC INJECTED MORPHINE ON CHEMICALLY INDUCED INFLAMMATION: AN EXPERIMENTAL ANIMAL STUDY

    1 Discipline of Pharmacology and Pharmacotherapy, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
    2 “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania

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  25. INVESTIGATING THE ANTIOXIDANT ACTIVITY, TOTAL PHENOLICS AND PHYTOCHEMICAL PROFILE IN AVICENNIA ALBA AND EXCOECARIA AGALLOCHA ROOT EXTRACTS AS A DEFENCE MECHANISM AGAINST POLLUTANTS

    1 Department of Marine Science, Faculty of Mathematics and Natural Sciences, Universitas Sriwijaya, Indralaya 30862, South Sumatra, Indonesia
    2 Environmental Management Study Program, Graduate Program, Universitas Sriwijaya, Palembang 30139, Indonesia

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