Farmacia Journal 4/2025
Volume 73 | Number 4 | Year 2025
Download this issue’s covers, and announcements
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MiRNAs: EMERGING DIAGNOSTIC AND THERAPEUTIC TARGETS FOR HEPATITIS C VIRUS-ASSOCIATED DISEASES
AMIN ULLAH 1,3, IRSHAD UR REHMAN 2, MARGARETE ODENTHAL 3, TARIQ NADEEM 4, QURBAN ALI 5*, MOHD AMIR 6, AJAZ AHMAD 7, AMAN ULLAH 8
1Department of Allied Health Science, Iqra National University Peshawar, 25000 Peshawar, Pakistan
2Centre for Biotechnology and Microbiology, University of Peshawar, 25000 Peshawar, Pakistan
3Institute of Pathology, University Hospital of Cologne, 50926 Cologne, Germany
4Centre of Excellence in Molecular Biology, University of the Punjab Lahore, Lahore, Pakistan
5Department of Plant Breeding & Genetics, Faculty of Agriculture Sciences, University of the Punjab, P.O. Box 54590, Lahore, Pakistan
6Department of Natural Products, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, 1982, Saudi Arabia
7Department of Clinical Pharmacy, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia
8Rehman college of allied health sciences, Rehman medical institute (RMI) Peshawar, 25000 Peshawar, Pakistan -
META-ANALYSIS OF CANNABIDIOL TREATMENT FOR SEIZURES ASSOCIATED WITH LENNOX-GASTAUT SYNDROME
JIE XU 1, YANBIN ZHANG 1, BAOXIAO WANG 1, CHENGHUI QIN 2*
1 Department of Neurology, First People’s Hospital of Linping District, Hangzhou, 311100, Zhejiang, China
2 Department of Neurology, Affiliated Hospital of Shaoxing University, Shaoxing，312000, Zhejiang, China -
MEASURING MEDICATION ADHERENCE IN ASTHMA PATIENTS IN DEVELOPING COUNTRIES: INSIGHTS FROM NORTH MACEDONIA
DIJANA MICEVA 1*, ZORICA NAUMOVSKA 2, DARINKA GJORGIEVA ACKOVA 1, KATARINA SMILKOV 1, BILJANA LAZAROVA 1,3, OLIVERA KRSTIC NAKOVSKA 4, SMILJKO JOVANOVSKI 4, DIMITAR KARKINSKI 4, BISTRA ANGELOVSKA 1, ELENA DRAKALSKA SERSEMOVA 1
1 Faculty of Medical Sciences, Goce Delcev University, Stip, Krste Misirkov Str., No. 10-A, P.O. Box 201, 2000 Stip, North Macedonia
2 Faculty of Pharmacy, Ss. Cyril and Methodius University in Skopje, Mother Teresa 47, 1000 Skopje, R.N. Macedonia,
3 Clinical hospital, Ljuben Ivanov bb, 2000 Stip, N. Macedonia
4 University Clinic of Pulmonology and Allergology, Majka Tereza 17, 1000 Skopje, Republic of North Macedonia -
META-ANALYSIS OF EFFECTIVENESS OF COMBINED SHUGAN JIEYU CAPSULES AND SELECTIVE SEROTONIN REUPTAKE INHIBITORS VERSUS MONOTHERAPY WITH SELECTIVE SEROTONIN REUPTAKE INHIBITORS IN PATIENTS WITH DEPRESSION
MINGXIU YU 1,2, WEI JI 2, YUANYUAN ZHANG 2, ZHIWEN SI 2, XIAOWEN YU 3, ZHENYUAN JIANG 3, ZHONGLIN WANG 3*
1 The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China
2 Deparment of Ultrasound, Affiliated Hospital of Shandong University of Chinese Medicine, Jinan, 250014, China
3 Department of Neurology, Affiliated Hospital of Shandong University of Chinese Medicine, Jinan, 250014, China -
ROLE OF PHYSICAL EXERCISE IN FRAILTY PREVENTION AMONG OLDER INDIVIDUALS WITH METABOLIC SYNDROME
COSTINA-DANIELA GÎȚĂ ¹#, JUSTIN AURELIAN ²#, MIRELA NEDELESCU ³, OANA KARAMPELAS ⁴*, ANA-GABRIELA PRADA ¹, SANDRA-MONICA GÎDEI ¹, OVIDIU ANDREI CIOCAN ¹, BLEBEA NICOLETA-MIRELA ⁵, VIVIANA ELIAN 6
1 “Carol Davila” University of Medicine and Pharmacy, Clinic of Geriatrics, Hospital of Chronic Diseases “Sf. Luca”, Bucharest, Romania
2 “Carol Davila” University of Medicine and Pharmacy, Department of Nursing, Bucharest, Romania
3 “Carol Davila” University of Medicine and Pharmacy, Department of Hygiene and Medical Ecology, Bucharest, Romania
4 “Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Bucharest, Romania
5 “Ovidius” University Constanța, Faculty of Pharmacy, Department of Pharmacotherapy, Constanța, Romania
6 “Carol Davila” University of Medicine and Pharmacy, Department of Diabetes, Nutrition and Metabolic Diseases, Bucharest, Romania -
CLINICAL PHARMACIST LED THERAPEUTIC DRUG MONITORING FOR VANCOMYCIN IN A ROMANIAN HOSPITAL
LIGIA-ANCUȚA HUI 1,2, CONSTANTIN BODOLEA 2,3, ANA-MARIA VLASE 4, ELISABETA IOANA HIRIȘCĂU 2,5, ANDREI-MIHAI BĂLAN 2,3, LAURIAN VLASE 1*, ADINA POPA 6
1 Pharmaceutical Technology and Biopharmacy Department, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012, Cluj-Napoca, Romania
2 ICU Department, University Clinical Municipal Hospital, 400139 Cluj-Napoca, Romania
3 ICU II Department, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400006, Cluj-Napoca, Romania
4 Pharmaceutical Botany Department, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012, Cluj-Napoca, Romania
5 Nursing Department, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400089, Cluj-Napoca, Romania
6 Clinical Pharmacy Department, Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012, Cluj-Napoca, Romania -
EVALUATION OF IN VITRO RELEASE PERFORMANCE OF SOFT GELATINE CAPSULES CONTAINING IBUPROFEN USING COMPENDIAL APPARATUS
CRISTINA ANAMARIA BUCIUMAN 1, LAURA GRAȚIELA VICAȘ 2, OCTAVIA GLIGOR 2*, DALIA SIMONA MIRON 3, FLAVIAN ȘTEFAN RĂDULESCU 3
1 “Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania
2 University of Oradea, Faculty of Medicine and Pharmacy, 10, 1 December Square, 410073, Oradea, Romania
3 Centre for Drug Sciences, Biopharmaceutics Laboratory, Faculty of Pharmacy, “Carol Davila’’ University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania -
EVALUATING THE RELATIONSHIP BETWEEN THE NUMBER OF DRUG INTERACTIONS AND TACROLIMUS EXPOSURE IN THE FIRST YEAR POST-KIDNEY TRANSPLANTATION: A COMPARATIVE STUDY OF INTERACTION DATABASES
NIKOLA STEFANOVIĆ 1*, MAŠA JOVIĆ 2, KATARINA DANKOVIĆ 2, IVANA DAMNJANOVIĆ 1, BRANISLAV APOSTOLOVIĆ 3, BRANKA MITIĆ 3,4, RADMILA VELIČKOVIĆ-RADOVANOVIĆ 3,5
1University of Nis, Faculty of Medicine, Department of Pharmacy, Dr Zorana Djindjica 81 Blvd., 18000 Nis, Serbia
2University of Nis, Faculty of Medicine, Dr Zorana Djindjica 81 Blvd., 18000 Nis, Serbia
3University Clinical Center Nis, Clinic of Nephrology, Dr Zorana Djindjica 48 Blvd., 18000 Nis, Serbia
4University of Nis, Faculty of Medicine, Department of Internal Medicine, Dr Zorana Djindjica 81 Blvd., 18000 Nis, Serbia
5University of Nis, Faculty of Medicine, Department of Pharmacology with toxicology, Dr Zorana Djindjica 81 Blvd., 18000 Nis, Serbia -
ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF CALCIUM SILICATE-BASED ENDODONTIC MATERIALS: A DISC DIFFUSION STUDY
ROXANA TALPOȘ-NICULESCU 1#, LUMINIȚA MARIA NICA 1#, LAURA CRISTINA RUSU 2, ADINA MARIANA MATICA 3, ȘERBAN TALPOȘ-NICULESCU 4*, MĂLINA POPA 5#, ION VALERIU CARABA 6,7, MARIOARA NICOLETA CARABA 7,8
1 Discipline of Restorative Dentistry and Endodontics, Research Center TADERP, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
2 Discipline of Oral Pathology, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
3 Department of Biology, Faculty of Chemistry-Biology-Geography, West University of Timișoara, 300315 Timișoara, Romania
4 Discipline of Oral and Maxillo-Facial Surgery, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300062 Timișoara, Romania
5 Discipline of Pedodontics, Pediatric Dentistry Research Center, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
6 Faculty of Bioengineering of Animal Resources, Banat University of Agricultural Sciences and Veterinary Medicine “King Mihai I of Romania” from Timișoara, Calea Aradului 119, RO 300645, Timișoara, Romania
7 ANAPATMOL Research Center, “Victor Babeș” University of Medicine and Pharmacy of Timișoara, 300041 Timișoara, Romania;
8 Cellular and Molecular Biology Department, “Victor Babeș” University of Medicine and Pharmacy of Timișoara, E. Murgu 2, Timișoara, 300041, Romania -
ANTIMICROBIAL SUSCEPTIBILITY OF BLACK-PIGMENTED PREVOTELLA STRAINS ISOLATED FROM THE OROPHARYNX IN DENTAL STUDENTS
GABRIELA BĂNCESCU #, ANDREEA CRISTIANA DIDILESCU #, LIDIA SFETCU *, CĂTĂLIN GAGIU †, VIOLETA DANIELA CĂRUNTU
Faculty of Dentistry, University of Medicine and Pharmacy ҅ ҅Carol Davila”, Bucharest, Romania
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DEVELOPMENT OF A METFORMIN MATRIX TABLET: A COMPARATIVE STUDY WITH MARKETED SUSTAINED RELEASE FORMULATION
MUTHANNA ABDULKARIM 1*, DOAA R ADAM 1, YUSRA AL ZAHRANI 1, NOURA BINSAEED 1, AIMAN Y. ALWADI 1, OMAR Z. AMEER 1, GAMAL M. MAHROUS 2
11Department of Pharmaceutical Sciences, College of Pharmacy, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia
2Department of Pharmaceutics, College of Pharmacy, King Saud University, PO Box 2457, Riyadh 11451, Saudi Arabia -
APPLICATION OF LC-MS FOR THE IDENTIFICATION AND QUANTIFICATION OF NITROSAMINE IMPURITIES IN ORAL METFORMIN-BASED PHARMACEUTICAL FORMULATIONS
ALINA BALINT 1*, LÉNARD FARCZÁDI 2, ANCA GABRIELA CÂRJE 1, VALENTIN ION 1, SILVIA IMRE 1, DANIELA LUCIA MUNTEAN 1
1 Department of Analytical Chemistry and Drug Analysis, Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540142, Romania
2 Center for Advanced Medical and Pharmaceutical Research, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540142, Romania -
THERAPEUTIC EFFICACY OF AMOXICILLIN COMBINED WITH METRONIDAZOLE IN TREATMENT OF PERIODONTITIS WITH TYPE II DIABETES AND TH1/TH2/TH17 STATUS
XUEWEI JIANG *
Department of Stomatology, Tongren Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200336, China
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POROUS GRAPHITIC CARBON COLUMN IN QUANTITATION OF CAFFEINE IN PRETERM INFANTS’ SERUM SAMPLES
ADELA-VALERIA NEAMȚU 1, COSTEL-VALENTIN MANDA 2*, OCTAVIAN CROITORU 2, MONICA DENISA ELENA POPESCU 2, DANIELA MARIA CALUCICĂ 2, JOHNY NEAMȚU 2, ANDREI BIȚĂ 2, LILIANA STANCA 1, MIRELA-ANIȘOARA SIMINEL 1, SIMONA-DANIELA NEAMȚU 2
1 Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Petru Rareș Street, 200638, Craiova, Romania
2 Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Petru Rareș Street, 200638, Craiova, Romania -
RHEOLOGICAL BEHAVIOR AND TEXTURE ANALYSIS OF OLEOGEL SUSPENSION CONTAINING CHONDROITIN SULFATE AND FUCOIDAN
JOZEF ZIMA 1#, EVA NOVÁKOVÁ 1,2#, MIROSLAVA ŠPAGLOVÁ 1, MIROSLAVA ŠUPOLÍKOVÁ 1,2*
1 Comenius University Bratislava, Faculty of Pharmacy, Department of Galenic Pharmacy, Odbojárov 10, 832 32 Bratislava, Slovak Republic
2 Comenius University Bratislava, Faculty of Natural Sciences, Department of Microbiology and Virology, Ilkovičova 6, Mlynská dolina, 842 15, Bratislava, Slovak Republic -
COMPLEMENTING NGS TISSUE BIOPSY WITH PLASMA DERIVED cFNA ANALYSIS AS A LIQUID BIOPSY FOR REAL-TIME THERAPY MODULATION IN COLORECTAL CANCER PATIENTS
MARIUS ZAMFIR 1,2#, ALEXANDRA PUȘCAȘU 3,4, ARIANA HUDIȚĂ 3*, BIANCA GĂLĂȚEANU 3, LAURA BUBURUZAN 5, ANCA MARIA IROFEI 5, CONSTANTIN BUSUIOC 6, MARA MARDARE 1,2,7, ALEXANDRU FILIPPI 8, GEORGE-TRAIAN-ALEXANDRU BURCEA-DRAGMIROIU 9, MIHAI TĂNASE 10, FLORIN GRAMA 11, NICULAE IORDACHE 7#, OCTAV GINGHINĂ 2,7, BOGDAN-COSMIN TĂNASE 12
1Doctoral School of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania
2Department of Surgery 3, “Prof. Dr. A. Trestioreanu” Institute of Oncology Bucharest, 022328, Bucharest, Romania
3Department of Biochemistry and Molecular Biology, University of Bucharest, 050095, Bucharest, Romania
4“Sfântul Ioan cel Nou” County Emergency Clinical Hospital, 720224, Suceava, Romania
5Department of Molecular Biology, Oncoteam Diagnostic SA, 010719, Bucharest, Romania
6Department of Pathology, “Prof Dr Matei Balș” National Institute of Infectious Diseases, 021105, Bucharest, Romania
7Faculty of Dentistry, “Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania
8Departament of Biochemistry and Biophysics, “Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania
9Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 050474, Bucharest, Romania
10Department of Surgery 1, “Carol Davila” Central Military Emergency University Hospital, 010825, Bucharest, Romania
11Department of General Surgery, Colțea Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy, 030171, Bucharest, Romania
12Department of Thoracic Surgery, “Prof. Dr. A. Trestioreanu” Institute of Oncology Bucharest, 022328, Bucharest, Romania -
DERMATOCOSMETIC EMULSIONS BASED ON ACMELLA OLERACEA EXTRACT: BIOCOMPATIBILITY AND TOLERABILITY STUDIES
CLAUDIA MAXIM 1#, DELIA TURCOV 2*, ANDREEA LUCA 2, MARIA BUTNARU 2, OANA TEODORA APREUTESEI 3#, RUXANDRA MIHAELA CRETU 3, ANCA ZBRANCA-TOPORAS 2, DANIELA ȘUTEU 1#
1 Faculty of Chemical Engineering and Environmental Protection ,,Cristofor Simionescu”, Technical University ,,Gheorghe Asachi” from Iași, 73A Prof. Dr. D.Mangeron Blvd., 700050, Iași, Romania
2 Faculty of Medical Bioengineering, University of Medicine and Pharmacy “Grigore T. Popa”, 700115 Iași, Romania
3 INCDSB ”Stejarul” Biological Research Center, Piatra Neamț, Romania -
GC-MS SPECTROSCOPIC APPROACH AND BIOACTIVITY POTENTIAL OF MARINE EXTRACTS FROM BLACK SEA CUCUMBER AND CROWN-OF-THORNS STARFISH INDIGENOUS TO ENGGANO ISLAND
ROZIRWAN 1*, ANNISA PUTRI SABILA 1, WIKE AYU EKA PUTRI 1, FAUZIYAH 1, MELKI 1, ISKHAQ ISKANDAR 2, ELA NOVIANTI 3, APON ZAENAL MUSTOPA 3, FATIMAH 3, NADILA NUR KHOTIMAH 4, REDHO YOGA NUGROHO 1
1Department of Marine Science, Faculty of Mathematics and Natural Sciences, Universitas Sriwijaya, Indralaya 30862, South Sumatra, Indonesia
2Department of Physics, Faculty of Mathematics and Natural Science, Sriwijaya University, Indralaya, South Sumatra, 30862, Indonesia
3Research Centre for Genetic Engineering, National Research and Innovation Agency, Bogor, West Java 16911, Indonesia
4Doctoral Program of Environmental Science, Postgraduate Program, Universitas Sriwijaya, Jl. Padang Selasa Bukit Besar, Palembang 30139, Indonesia -
EVALUATION OF ANTITUMOUR, ANTIBACTERIAL AND ANTIOXIDANT EFFECTS OF HYDROALCOHOLIC EXTRACTS FROM LEMON BALM LEAVES AND STEMS
IOAN-ALEXANDRU CÎMPEANU 1#, DALIBORCA VLAD 2#, MIHAELA BOTA 3*, LAVINIA VLAIA 3,4, DELIA MUNTEAN 5,6, IASMINA-ALEXANDRA PREDESCU 7,8, DAN ILIESCU 9
1Doctoral School, Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
2Biochemistry and Pharmacology Department, Discipline of Pharmacology, Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
3Department II—Pharmaceutical Technology, Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
4Formulation and Technology of Drugs Research Centre, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
5Department of Microbiology, Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
6Multidisciplinary Research Centre on Antimicrobial Resistance, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania
7Research Centre for Pharmaco-Toxicological Evaluation, Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
8Discipline of Toxicology, Drug Industry, Management and Legislation, Faculty of Pharmacy, “Victor Babeş” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
9University Clinic of Surgical Semiology I and Thoracic Surgery, Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timișoara, Romania -
UNVEILING ACUTE AND 28-DAY ORAL TOXICITIES OF CHEMICALLY CHARACTERISED AQUEOUS EXTRACT OF RUBUS FRUTICOSUS L. IN MICE
YAHYA EL-MERNISSI 1,2*, NAOUAL EL MENYIY 2, AZIZ ZOUHRI 3, AMINA LABHAR 1, RAFIK EL-MERNISSI 3, RABIE KACHKOUL 4,5, M’HAMED AHARI 1, AMIN SALHI 1, MOHAMMED BOURHIA 6, AMIRA METOUEKEL 6, GAMAL A. SHAZLY 7, LHOUSSAIN HAJJI 3, HASSAN AMHAMDI 1
1Applied chemistry team, Faculty of Sciences and Techniques, Abdelmalek Essaadi University, 32 003 Al Hoceima, Morocco
2Laboratory of Pharmacology, National Agency of Medicinal and Aromatic Plants, Taounate 34025, Morocco
3Bioactives and Environmental Health Laboratory, Faculty of Sciences, Moulay Ismail University, Meknes B.P. 11201, Morocco
4Higher Institute of Nursing Professions and Health Techniques of Fez, Ministry of Health and Social Protection, EL Ghassani Hospital, Fez 30000, Morocco
5Laboratory of Biotechnology and Natural Resources Valorisation, Faculty of Sciences, Ibn Zohr University, 80060, Agadir, Morocco
6University of Technology of Compiègne, EA 4297 TIMR, 60205 Compiègne Cedex, France
7Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia -
COMPARATIVE SAFETY AND TOLERABILITY OF THE SHORT-COURSE BPaLM REGIMEN VERSUS CONVENTIONAL THERAPY FOR MDR-TB: A RETROSPECTIVE COHORT STUDY FROM A TERTIARY PULMONOLOGY HOSPITAL IN ROMANIA
ANTONELA DRAGOMIR 1,2,3, BEATRICE MAHLER 1,2,3, SILVIU VLĂSCEANU 5,3, ANCA FÂCĂ 3,6, EMILIA HOMEA 3, TEODORA MELINTE 3, DRAGOȘ BĂICEANU 4, TRAIAN PANCIU 4, ELMIRA IBRAIM 4, ALEXANDRU STOICHIȚĂ 1,2,3,4*
1 Pneumology II Department, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2 Pneumology Clinic, “Marius Nasta” Institute of Pneumology, Bucharest, Romania
3 Faculty of Medicine, “Marius Nasta” University of Medicine and Pharmacy, Bucharest, Romania
4 Research Department, “Marius Nasta” Institute of Pneumology, Bucharest, Romania
5 Thoracic Surgery Department, “Marius Nasta” Institute of Pneumology, Bucharest, Romania
6 Clinical Pharmacy Department, “Marius Nasta” Institute of Pneumology, Bucharest, Romania -
FORMULATION OF TABLETS CONTAINING NEWLY SYNTHESIZED pH-SENSITIVE POLYMER FOR ORAL USE OF 5-FLUOROURACIL AS A SAFE TREATMENT OF COLORECTAL CANCER
TEODORA POPOVA 1*, MARTA SLAVKOVA 1, BORISLAV TZANKOV 1, DENITSA STEFANOVA 2, VIRGINIA TZANKOVA 2, CHRISTINA VOYCHEVA 1
1 Department of Pharmaceutical Technology and biopharmacy, Faculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria
2 Department of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria -
PHYTOCHEMICAL PROFILING AND ANTIOXIDANT PROPERTIES OF AJANIA FASTIGIATA (C. WINKL.) POLJAKOV (ASTERACEAE)
ASEM MAMUROVA 1, GULZAT KAIRANOVA 1*, GAUKHAR AMERTAYEVA 1, NURSULU AKHTAYEVA 1, AHMET BEYATLI 2, LASHYN KIYEKBAYEVA 3, ZHANAR ISKAKOVA 4, KAIRAT ZHALDYBAEV 5, KLARA ZHUMALINA 5
1 Department of Biodiversity and Bioresources, al-Farabi Kazakh National University, Almaty, Kazakhstan
2 Department of Medicinal and Aromatic Plants, University of Health Science, Istanbul, Turkey
3 Pharmaceutical school, Asfendiyarov Kazakh National Medical University; Almaty, Kazakhstan
4 Research Institute of New Chemical Technologies ENU named after L.N. Gumilyov; Astana, Kazakhstan
5 Kazakh-Russian Medical University in Kazakhstan, Almaty, Kazakhstan -
THE IMPORTANCE OF THE MEDICAL TEAM IN THERAPEUTIC SUCCESS. THE UNDERUTILISED CLINICAL PHARMACIST
ANDREEA SĂLCUDEAN 1#, BIANCA-EUGENIA ŐSZ 2*, EDUARD-CRISTIAN ENACHE 1, GEORGE JÎTCĂ 2, RAMONA AMINA POPOVICI 3#, IUSTIN OLARIU 4#, ALEXANDRA GROȘAN 2, ANCA MEDA VĂSIEȘIU 5
1 Department of Ethics and Social Sciences, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540142, Romania
2 Department of Pharmacology and Clinical Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540142, Romania
3 Department of Management and Communication in Dental Medicine, Department I, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy of Timișoara, Romania
4 Department of Dentistry, Faculty of Dentistry, “Vasile Goldiș” Western University of Arad, 310025, Arad, Romania
5 Department of Infectious Diseases, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540142, Târgu Mureș, Romania -
COMPARATIVE ANALYSIS OF THE TIME TO MARKET ACCESS IN BULGARIA, POLAND AND ROMANIA FOR MEDICINES WITH MARKETING AUTHORISATION UNDER THE EMA’S EARLY ACCESS-SPECIFIC PROCEDURES
MARIA DIMITROVA 1, ADINA TURCU-ȘTIOLICĂ 2*, IVO TSEKOV 1, PAWEL KAWALEC 3, RAFAL NOWAK 3, GUENKA PETROVA 1
1 Medical University of Sofia, Faculty of Pharmacy, Department of Organization and Economy of Pharmacy, 2-Dunav Street, 1000, Sofia, Bulgaria
2 University of Medicine and Pharmacy of Craiova, Faculty of Pharmacy, 2-4 Petru Rareș Street, 200349, Craiova, Romania
3 Institute of Public Health, Jagiellonian University Medical College, Faculty of Health Sciences, Department of Nutrition and Drug Research, Krakow, Poland