Romanian Society of Pharmaceutical Sciences

Farmacia Journal 3/2024

Volume 72 | Number 3 | Year 2024

Download this issue’s covers, and announcements.

  1. SUNSCREEN TOPICAL PRODUCTS – FROM CONVENTIONAL TO NOVEL FORMULATIONS

    1“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, 6 Traian Vuia Street, 020945, Bucharest, Romania
    2 “Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Management and Marketing, 6 Traian Vuia Street, 020945, Bucharest, Romania
    3 “Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, Department of Family Medicine, 8 Eroii Sanitari Boulevard, 050474, Bucharest, Romania

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  2. INVESTIGATING THE PHYSICOCHEMICAL, NON-CLINICAL, AND CLINICAL CRITERIA FOR ASSESSING COMPARABILITY IN RANIBIZUMAB BIOSIMILARS: A COMPREHENSIVE REVIEW

    Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan

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  3. ASSESSMENT OF RELATIVE BIOAVAILABILITY OF TWO INDAPAMIDE TABLET FORMULATIONS AFTER ADMINISTRATION OF SINGLE DOSES TO FASTED CAUCASIAN SUBJECTS IN 2-WAY CROSSOVER STUDY

    1Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
    2 Regulatory Affairs Department, Antibiotice SA, Iași, Romania
    3 Centre for Drug Evaluation, Antibiotice SA, Iași, Romania
    4 Department of Pharmaceutical Botany, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

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  4. EFFECTS OF H4415 ON PAIN SENSITIVITY IN RAT

    1Grigore T. Popa" University of Medicine and Pharmacy, Iași, Romania
    2 Center of Biomedical Research, Romanian Academy, Iași branch, Romania
    3 Advanced Center for Research and Development in Experimental Medicine, Prof. Ostin C. Mungiu", CEMEX, "Grigore T. Popa" University of Medicine and Pharmacy, Iași, Romania

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  5. IN VITRO BIOCOMPATIBILITY AND IN OVO IRRITANT POTENTIAL SCREENING OF TWO CLEAR ALIGNERS WITH ORTHODONTIC APPLICATIONS

    1Department of Pedodontics, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy Timisoara, 9 Revoluției 1989 Boulevard, 300041, Timișoara, Romania
    2 Pediatric Dentistry Research Centre, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy Timisoara, 9 Revoluției Boulevard, 300041, Timișoara, Romania
    3 “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115, Iași, Romania
    4 Department of Preventive, Community Dentistry and Oral Health, Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy Timisoara, 14A Tudor Vladimirescu Avenue, 300173, Timișoara, Romania
    5 ⁠Translational and Experimental Clinical Research Centre in Oral Health, “Victor Babeș” University of Medicine and Pharmacy Timisoara, 14A Tudor Vladimirescu Avenue, 300173, Timișoara, Romania
    6 Department of Orthodontics, Faculty of Dental Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universității Street, 700115, Iași, Romania
    7 Department of Orthodontics, Faculty of Dental Medicine, “Victor Babeş” University of Medicine and Pharmacy Timisoara, 9 No., Revolutiei Bv., 300041 Timişoara, Romania
    8 Orthodontic Research Centre (ORTHO-CENTER), “Victor Babeș” University of Medicine and Pharmacy Timișoara, Timișoara, Romania
    9 Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
    10 Research Centre for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
    11 Department of Dental Aesthetics, Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, 9 Revoluției Boulevard, 300041, Timișoara, Romania

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  6. THE ANTI-AGEING POTENTIAL OF LITSEA OPPOSITIFOLIA STEM EXTRACT: EVIDENCE FROM IN VITRO AND EX VIVO STUDY ON SKIN CELL LINES

    1Faculty of Pharmacy, University Of Indonesia, Depok 16424, Indonesia
    2 Indonesia International Institute For Life Sciences, East Jakarta 13210, Indonesia

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  7. INVESTIGATION OF ANTIMICROBIAL ACTIVITY AND RHEOLOGICAL PROPERTIES OF CHITOSAN-AND ALGINATE-BASED HYDROGELS ENRICHED WITH VOLATILE OILS FOR BIOMEDICAL APPLICATIONS

    1Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila”, 020956, Bucharest, Romania
    2 Institute of Physical Chemistry – Ilie Murgulescu, Romanian Academy, 060021, Bucharest, Romania
    3 Department of Microbiology, Faculty of Biology, University of Bucharest, 1-3 Portocalilor Street, 060101, Bucharest, Romania

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  8. INFLUENCE OF DUAL-RESPONSIVE OXALIPLATIN (L-OHP)-/ NARINGIN (NAR) DRUG DELIVERY SYSTEM ON THE GROWTH OF COLORECTAL TUMORS AND THE IMMUNE MICROENVIRONMENT

    Department of Gastroenterology, Jingzhou Central Hospital, Yangtze University, Jingzhou, 434020, Hubei, China

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  9. BENEFITS OF SEA BUCKTHORN FRUIT OIL AS ADJUVANT THERAPY IN RHEUMATOID ARTHRITIS

    1Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy, 16, Universitatii Str., 700115, Iasi, Romania
    2 Clinical Rehabilitation Hospital, 14, Pantelimon Halipa Str., 700661, Iasi, Romania
    3 Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16, Universitatii Str., 700115, Iasi, Romania
    4 Advanced Research and Development Centre for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy, 9-13, Mihail Kogalniceanu Str., 700259, Iasi, Romania
    5 Medical Investigations Praxis SRL, 35, Moara de Vant Str., 700376, Iasi, Romania
    6 Laboratory of Physical Chemistry of Polymers, Petru Poni Institute of Macromolecular Chemistry, 41A, Grigore Ghica Voda Al., 700487, Iasi, Romania

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  10. RFA-INDUCED ALTERATIONS IN THE EXPRESSION OF PD-1 AND CTLA-4 IN THE TUMOUR MICROENVIRONMENT pCCA: RESULTS FROM AN EXPLORATORY STUDY

    1Faculty of Biology, University of Bucharest, Bucharest, Romania
    2 Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    3 Department of Surgery 3, “Prof. Dr. Al. Trestioreanu” Institute of Oncology, Bucharest, Romania
    4 Research Institute of the University of Bucharest, University of Bucharest, Bucharest, Romania
    5 The University of York, York, United Kingdom
    6 Doctoral School of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    7 Central University Hospital Saint-Etienne, Saint-Etienne, France
    8 Gastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania
    9 Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    10 Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

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  11. THE CORRELATION BETWEEN NUTRITIONAL STATUS AND MUSCLE STRENGTH, AND DYNAMOMETRY IN PATIENTS WITH LIVER CIRRHOSIS IN IRAQ

    1Faculty of Health Sciences, American University of Madaba, Madaba, Jordan
    2 Faculty of Pharmacy, Bilad Alrafidain University College, Diyala, Iraq
    3 Department of Pharmacy, AL Mustafa University College, Baghdad, Iraq
    4 Pharmacological and Diagnostic Research Centre, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan
    5 Dr Hany Akeel institute, Iraqi Medical Research Centre, Baghdad, 10001, Iraq
    6 Department of Pharmacy, Damascus University, Syria

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  12. OUTCOME OF CO-ADMINISTRATION OF SEA BUCKTHORN FRUIT IN HIGH FAT DIET WISTAR RATS

    1Romano-American University, Bucharest, Romania
    2 “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    3 University of Agronomic Sciences and Veterinary Medicine, Bucharest, Romania

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  13. THERAPEUTIC STRATEGIES AND USE OF LOPINAVIR/RITONAVIR IN PATIENTS WITH HIGHLY RESISTANT HUMAN IMMUNODEFICIENCY VIRUS

    1Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, China
    2 MOE Key Laboratory of Tumour Molecular Biology, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University First Affiliated Hospital, Guangzhou, Guangdong, China
    3 Department of Infection and Immunology, The First Hospital of Changsha City, Changsha, 410000, Hunan, China

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  14. A QUALITY BY DESIGN APPROACH TO OPTIMISE THE TRANSFECTION EFFICIENCY OF POLY(AMIDOAMINE)-BASED NANOPARTICLES WITH mRNA

    1Doctoral School in Integrative Biology, Faculty of Biology and Geology, “Babeș-Bolyai” University, 400015 Cluj-Napoca, Romania
    2 Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy “Iuliu Hațieganu”, 400010, Cluj-Napoca, Romania
    3 Department of Molecular Biology and Biotechnology, Centre of Systems Biology, Biodiversity and Bioresources, Faculty of Biology and Geology, “Babeș-Bolyai” University, 400015 Cluj-Napoca, Romania

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  15. PHYTOCHEMICAL PROFILING BY LC-HRMS AND ANTIOXIDANT ACTIVITY OF BLUMEA BALSAMIFERA LEAVES EXTRACT BASED ON DIFFERENCES IN THE GROWING LOCATION AND EXTRACTING SOLVENT

    1Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Jalan Tanjung Kampus IPB Dramaga, Bogor 16880, Indonesia
    2 Tropical Biopharmaca Research Centre, Institute of Research and Community Services, IPB University, Jalan Taman Kencana No. 3 Kampus IPB Taman Kencana, Bogor 16128, Indonesia
    3 Department of Chemistry, Faculty of Mathematics and Natural Sciences, Pakuan University, Bogor 16143, Indonesia
    4 Advance Research Laboratory, IPB University, Jalan Palem Kampus IPB Dramaga, Bogor 16680, Indonesia
    5 Division of Pharmacology, Department of Anatomy, Physiology and Pharmacology, School of Veterinary Medicine and Biomedical Sciences, IPB University, Kampus IPB Dramaga, Bogor, Indonesia

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  16. GENISTEIN AND QUERCETIN TRIGGER CYTOTOXICITY, APOPTOSIS, AND OXIDATIVE STRESS IN SK-MEL-28 CUTANEOUS MELANOMA CELLS

    1Faculty of Medicine, "Vasile Goldiș" Western University of Arad, 94 Revolutiei Blvd., 310130, Arad, Romania
    2 Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square 2, 300041, Timișoara, Romania
    3 Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square 2, 300041, Timișoara, Romania
    4 Research Centre for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square 2, 300041, Timișoara, Romania
    5 CBS Medcom Hospital, 12th Popa Sapca Street, 300047 Timisoara, Romania

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  17. FLAVONOID-RICH EXTRACT OF VARTHEMIA IPHIONOIDES INCREASED LOW-DENSITY LIPOPROTEIN RECEPTOR AND DECREASED HYDROXYMETHYLGLUTARYL COA REDUCTASE EXPRESSION IN HEPG2 CELLS

    1Department of Medical Lab. Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman, Jordan
    2 Pharmacognosy Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
    3 Pharmacognosy Department, Faculty of Pharmacy, Sinai University – Kantara Branch, Ismailia, Egypt
    4 Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
    5 Biochemistry Department, Faculty of Pharmacy, Sinai University – Kantara Branch, Ismailia, Egypt

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  18. HLA HAPLOTYPES AND THE RISK OF SEVERE GLYCAEMIC ONSET IN NEWLY DIAGNOSED TYPE 1 DIABETIC PATIENTS FROM ROMANIA: A SINGLE-CENTRE PILOT COHORT STUDY

    1“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    2 Department of Endocrinology, Diabetes, Nutrition and Metabolic diseases, Elias Hospital, 011461, Bucharest, Romania
    3 HLA Laboratory, “C.T. Nicolau” National Institute of Blood Transfusion, 011154, Bucharest, Romania
    4 The Immunology Laboratory, Elias Hospital, 011461, Bucharest, Romania

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  19. ACUTE AND SUBACUTE TOXICITY STUDY OF LAPORTEA DECUMANA LEAF EXTRACT IN RATS

    1Graduate Program, Magister of Pharmacy Program, Faculty of Pharmacy, Hasanuddin University, Makassar, 90245, Indonesia
    2 Laboratory of Clinical Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, 90245, Indonesia
    3 Laboratory of Phytochemistry, Faculty of Pharmacy, Hasanuddin University, Makassar, 90245, Indonesia
    4 Department of Physiology, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia
    5 Drug Discovery and Development Research Center of Hasanuddin University, Makassar, 90245, Indonesia

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  20. DIABETIC FOOT CARE RECOMMENDATIONS – PATIENT BEHAVIOURAL TRENDS

    1Department of Pharmacodynamics and Clinical Pharmacy,”Grigore T. Popa” University of Medicine and Pharmacy of Iași
    2 Center for Biomedical Research, Romanian Academy, Iași Branch
    3 Department of Computer Science,”Alexandru Ioan Cuza” University of Iași

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  21. ASSOCIATION OF NFE2L2 GENE POLYMORPHISM (rs35652124) WITH DEVELOPMENT OF RETINOPATHY IN IRAQI TYPE 2 DIABETIC PATIENTS, IN RELATION TO VASCULAR ENDOTHELIAL GROWTH FACTOR AND ENDOCAN SERUM LEVELS

    1Clinical Laboratory Sciences Department, College of Pharmacy, University of Baghdad, Iraq

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  22. QUALITY OF LIFE OF ROMANIAN PATIENTS WITH SENSITIVE AND DRUG-RESISTANT TUBERCULOSIS DURING AND AFTER TREATMENT

    1“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
    2 “Marius Nasta” Institute of Pneumology, Bucharest, Romania

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  23. POTENTIALLY INAPPROPRIATE PRESCRIBING IN ELDERLY PATIENTS ACROSS HEALTHCARE SETTINGS: APPLICATION OF STOPP/START VERSION 2 CRITERIA

    1University of Belgrade - Faculty of Pharmacy, Department of Pharmacokinetics and Clinical Pharmacy, Vojvode Stepe 450, 11221, Belgrade, Republic of Serbia
    2 University of Niš - Faculty of Medicine, Department of Pharmacy, Dr Zorana Đinđića 81 Blvd., 18000, Niš, Republic of Serbia
    3 University of Niš - Faculty of Medicine, Department of Pharmacology with Toxicology, Dr Zorana Đinđića 81 Blvd., 18000, Niš, Republic of Serbia
    4 University Clinical Center Niš, Clinic of Nephrology, Dr Zorana Đinđića 48 Blvd., 18000, Niš, Republic of Serbia

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  24. QUANTIFYING THE QUALITY OF SERVICES IN COMMUNITY PHARMACIES IN ROMANIA – DESIGNING AND APPLYING A QUESTIONNAIRE AMONG PHARMACEUTICAL STAFF

    “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania

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  25. EXPLORING THE CONSCIENCE CLAUSE FOR PHARMACISTS IN THE EU COUNTRIES

    Department of Pharmaceutical Legislation and Management, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, 12 Ion Creangă Street, 400010, Cluj-Napoca, Romania

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