Romanian Society of Pharmaceutical Sciences

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THERAPEUTIC POTENTIAL OF HYSSOPUS OFFICINALIS L. IN SKIN PROBLEMS – A REVIEW

TIJANA MIĆOVIĆ 1,2*, JELENA S. KATANIĆ STANKOVIĆ 3

1 Institute for Medicines and Medical Devices of Montenegro, Bulevar Ivana Crnojevića 64a, 81000 Podgorica, Montenegro
2 University of Montenegro, Faculty of Medicine, Kruševac bb, 81000 Podgorica, Montenegro
3 Institute for Information Technologies Kragujevac, Department of Science, University of Kragujevac, Jovana Cvijića bb, 34000 Kragujevac, Serbia

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The aim of this review is to evaluate the potential of Hyssopus officinalis L., commonly known as hyssop, in addressing specific dermatological concerns based on existing research evidence. The review presents an analysis of the composition of essential oils and extracts derived from Hyssopus officinalis L. It encompasses a comprehensive examination of the pharmacological activities associated with hyssop herb essential oils/extracts, particularly in the context of dermatological concerns. Existing studies suggest promising potential for hyssop essential oil/extracts in addressing various skin conditions, including microbial skin infections, inflammatory diseases and oxidative stress-related skin damage. There are also data on potential cytotoxic, antigenotoxic and antimelanogenic effects. Furthermore, this review highlights the predominant compounds present in hyssop essential oil and extracts, elucidating their role as potential carriers of pharmacological activity. In the conclusion, the key findings of the review are summarized, emphasizing the promising attributes of Hyssopus officinalis L. for skin health. However, it also underscores the importance of addressing existing gaps in research and conducting clinical trials and additional studies to ensure the efficacy and safety of hyssop herb in dermatological applications.