Romanian Society of Pharmaceutical Sciences
 

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THE DEVELOPMENT OF COMPOSITION AND CHARACTERIZATION OF BIODEGRADABLE HEMOSTATIC AND ABSORBABLE SPONGES FOR MEDICAL APPLICATION

BOHDANA PAVLIUK 1*, MARIANA CHUBKA 2, TARAS HROSHOVYI 1

1.Department of Pharmacy Management, Economics and Technology, “I. Horbachevsky” Ternopil National Medical University, Ternopil, Ukraine
2.Department of Pharmacy, Educational Scientific Institute of Postgraduate Education, “I. Horbachevsky” Ternopil National Medical University, Ternopil, Ukraine

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The aim of this work was to develop and characterize a soft structured absorption sponge intended to stop bleeding. The medical sponge was prepared based on xenoderm water extract and adding chlorhexidine digluconate (1%). The influence of excipients and their amounts on the quality of sponges (stability, degradation rate, morphological structure, percentage of water absorption, biological evaluation and haemostatic effect) were studied. The experimental results clearly confirmed that the medical sponges developed in this study could be suitable for haemostasis and can be used in medical practice.