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TEXTURE ANALYSIS AND COMPARATIVE SCREENING OF THE SENSORY PROPERTIES OF NEW SKINCARE PRODUCTS

MAGDALENA BÎRSAN 1,2, ALIN-VIOREL FOCȘA 2, ȘADIYE-IOANA SCRIPCARIU 3, PAULA ANTONOAEA 4*, CEZARA PINTEA 4, ROBERT ALEXANDRU VLAD 4, MIHAELA MONICA SCUTARIU 5, ADRIANA CIURBA 4

1 Medicine and Pharmacy Doctoral School, “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 38 Gheorghe Marinescu Street, 540142, Târgu Mureș, Romania
2 “Grigore T. Popa” University of Medicine and Pharmacy from Iași, Faculty of Pharmacy, Department of Drug Industry and Pharmaceutical Biotechnology, 16 Universității Street, 700115, Iași, Romania
3 “Grigore T. Popa” University of Medicine and Pharmacy from Iași, Faculty of Medicine, Mother and Child Health Department, 16 Universităţii Street, 700115, Iași, Romania
4 “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, 38 Gheorghe Marinescu Street, 540142, Târgu Mureș, Romania
5 “Grigore T. Popa” University of Medicine and Pharmacy from Iași, Faculty of Dental Medicine, 16 Universităţii Street, 700115, Iași, Romania

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Personalized cosmetic products have emerged as a preferred choice for consumers, primarily due to their demonstrated efficacy over time. This study aimed to develop and comparatively evaluate two new skincare products utilizing both classical and automated manufacturing methods. The primary focus was on assessing the textural characteristics of these formulations through reverse extrusion measurements, conducted using the TA.XT Plus equipment (Stable Micro Systems, Godalming, UK). The results indicated that both products exhibited superior firmness, consistency and adhesiveness when produced via the automated method. A statistically significant correlation was found within the internal groups between the traditional and automated preparation methods (p < 0.01). Furthermore, both formulations underwent rigorous testing for perception and safety in a cohort of healthy female subjects aged 45 to 65 years. After a 28-day application period, the subjects reported a 100% satisfaction rate with both anti-wrinkle formulas.