Romanian Society of Pharmaceutical Sciences
 

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ASSESSMENT OF ANTIOXIDANT CAPACITY OF SOME EXTRACTS FOR FURTHER USE IN THERAPY

LAURA VICAȘ1, ALIN TEUȘDEA2, SIMONA VICAȘ2*, ELEONORA MARIAN1, JURCA TUNDE1, MARIANA MUREȘAN1, FELICIA GLIGOR3

1.University of Oradea, Medicine and Pharmacy Faculty, Oradea, Romania
2 .University of Oradea, Faculty of Environmental Protection, Oradea, Romania
3 .University Lucian Blaga Sibiu, The Faculty of Medicine, Sibiu, Romania

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Salviae and Plantago species are plants known as having antioxidant effects. The aim of the study was to compare in vitro the antioxidant capacity of these medicinal plants from two different areas of Romania (Bihor and Arad counties) in order to use it in the future in the field of pharmacology and medicine. An UV-Vis spectra fingerprint (250-800 nm) of ethanol extracts from Salviae and Plantago species was recorded in order to establish the maximum absorption, specifically bioactive compounds. The bioactive compounds from those two extracts, polyphenols types were determined by the Folin-Ciocalteu method, and the total flavonoids have been determined through a spectrophotometric method. Antioxidant capacity of the extracts was evaluated by the following methods: DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2'-Azinobis [3-ethylbenzothiazoline-6-sulfonic acid]-diammonium salt) and FRAP (the Ferric reducing antioxidant power). The results shown, that Salviae species are rich in polyphenols, while Plantago is rich in flavonoids being a good reason for their association.