Romanian Society of Pharmaceutical Sciences
 

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ADVANCES IN RESEARCH OF NEW 2-((4-ETHYLPHENOXY)METHYL)- N-(ARYLCARBAMOTHIOYL)BENZAMIDES

CARMEN LIMBAN1, ALEXANDRU VASILE MISSIR1, DIANA CAMELIA NUŢĂ1*, MIRON TEODOR CĂPROIU2, LAURENȚIU MORUSCIAG1, CORNEL CHIRIŢĂ1, AILIN CUPII1, HOREA GURGU1

1.University of Medicine and Pharmacy “Carol Davila” Bucharest, Faculty of Pharmacy, Bucharest, Romania, 6 Traian Vuia St., Bucharest, 020956, Romania
2 .The Organic Chemistry Center of Romanian Academy “C. D. Neniţescu”, 202B Splaiul Independenţei, Bucharest, Romania

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The therapeutic importance of benzamides and the encouraging results obtained on N-(arylcarbamothioyl)benzamides led us to continue the synthesis in this class of compounds. Thus, new compounds were synthesized by reacting 2-(4- ethylphenoxymethyl)benzoyl isothiocyanate (6) with various amines and their structures were established by IR, 1H-NMR, 13C-NMR spectroscopy and C, H, N, S elemental analysis.