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ULTRASOUND CARDIOGRAPHY EVALUATION OF THE THERAPEUTIC EFFECTS OF GAMMA GLOBULIN IN COMBINATION WITH A GLUCOCORTICOID IN SEVERE MYOCARDITIS IN ADULTS

YING HUANG, MAOJUAN WANG *

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In this study, the clinical efficacy of gamma globulin in combination with glucocorticoid therapy in severe viral myocarditis in adults was analysed using ultrasound cardiography. A total of 120 hospitalised severe viral myocarditis patients were included. They were divided into an observation group (60 cases treated with intravenous injections of gamma globulin and glucocorticoid based on routine therapy) and a control group (60 cases treated with glucocorticoid based on routine therapy). The mortality, cure and relapse rates of both groups were analysed. Ultrasound cardiography was used to evaluate the changes in cardiac function in combination with myocardial enzyme evaluation before and after treatment. Healing rates in the observation group were significantly higher than in the control group. After therapy, cardiac troponin T (cTnT), creatine kinase MB (CK-MB), brain natriuretic peptide (BNP), casein kinase (CK) and lactate dehydrogenase (LDH) levels were significantly higher in the observation group than in the control group (p < 0.05). The overall response rate in the observation group (98.33%) was significantly higher than in the control group (88.33%) (p < 0.05). Ultrasonocardiography had a very high value in the diagnosis of myocarditis. Gammaglobulin combined with glucocorticoid therapy was effective in the treatment of severe myocarditis.