TRANEXAMIC ACID – MAKING MASSIVE BODY WEIGHT LOSS SKIN REDUCING SURGERY EASIER AND SAFER
CARMEN GIUGLEA 1,2#, ELENA-CRISTINA BURLACU 1*, LAVINIA ALICE BĂLĂCEANU 1,2#,
GEORGE TRAIAN ALEXANDRU BURCEA-DRAGOMIROIU 2#, IULIA MIHAELA GAVRILĂ 1,2, ANDREI MARIN 1,2, SILVIU-ADRIAN MARINESCU 2,3
1“Sf. Ioan” Clinical Emergency Hospital, Bucharest, Romania
2“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania 3“Bagdasar-Arseni” Clinical Emergency Hospital, Bucharest, Romania
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Plastic and aesthetic procedures in patients with massive body weight loss require a careful management regarding the correct strategy implemented prior, during and following surgery. Post-operative haemorrhage and haematoma formation are some of the most undesirable complications that often need reinterventions. Tranexamic acid (TXA) is a synthetic antifibrinolytic pharmaceutic drug that suppress of the lysine binding sites of plasminogen to plasmin by precluding plasminogen from fastening to the fibrin molecule. Its role is to decrease perioperative blood loss. The authors assessed their experience with 70 consecutive patients that underwent lower body lift surgery from July 2018 to July 2021. They were divided into 2 groups, 35 of them received perioperative TXA and another 35 served as control (no TXA). We assessed the complication rates, blood loss and transfusion risk in the 2 groups to demonstrate the efficiency of TXA as a support in the surgical protocol. This study shows that the use of TXA in patients with massive body weight loss skin reducing surgery has a significant role in perioperative blood loss and its complications.
