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THE SYNTHESIS OF SOME NEW ACYLOXIMINES COMPOUNDS WITH POTENTIAL PHARMACOLOGICAL ACTIVITY

DANA MIHAELA CIOROIANU¹, DIANA CAMELIA NUȚĂ^1*, LAURENȚIU MORUȘCIAG¹, MIRON TEODOR CĂPROIU², ILEANA CORNELIA CHIRIȚĂ¹, CARMEN LIMBAN¹

1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, „Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
² The Organic Chemistry Center of Romanian Academy “C.D. Nenițescu”, Splaiul Independenței 202B, Bucharest, Romania

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In our search of bioactive molecules we synthesized some new substances with heterocyclic structure which might become new compounds with pharmacological properties similar with the tricyclic antidepressants. These new substances are O-acyloximine derivatives with 10,11-dihydro-5H-dibenzo[a,d]cycloheptadienic structure. The structures of these new compounds were confirmed by elemental analysis, infrared and Nuclear magnetic resonance (NMR) spectra.

« Back to Farmacia Journal 2/2013

THE SYNTHESIS OF SOME NEW ACYLOXIMINES COMPOUNDS WITH POTENTIAL PHARMACOLOGICAL ACTIVITY

DANA MIHAELA CIOROIANU1, DIANA CAMELIA NUȚĂ1*, LAURENȚIU MORUȘCIAG1, MIRON TEODOR CĂPROIU2, ILEANA CORNELIA CHIRIȚĂ1, CARMEN LIMBAN1

DANA MIHAELA CIOROIANU¹, DIANA CAMELIA NUȚĂ^1*, LAURENȚIU MORUȘCIAG¹, MIRON TEODOR CĂPROIU², ILEANA CORNELIA CHIRIȚĂ¹, CARMEN LIMBAN¹