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THE STUDY OF PHARMACOPOEIAS USED IN THE ROMANIAN AREA IN XVIII-XXTH CENTURIES: EVOLUTION OF PROPORTIONS FOR DRUG SUBSTANCES AND PHARMACEUTICAL PREPARATIONS

EMILIA STANCU, ANA CARATA, ADRIANA-ELENA TĂEREL^*, VALENTINA SOROCEANU

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The main function of Pharmacopoeias is to officially regulate the quality of medicines. Indirectly, Pharmacopoeias allow also the reestablishment of the pharmacological picture for the period they were in force, medicinal substances and pharmaceutical preparations used in therapy being included as individual monographs. Depending on the progress and needs in therapeutic practice, successive editions of the Pharmacopoeia recorded changes. Relating to the introduction of new monographs or removing those outdated and change in percentage of representation for various categories of medicinal substances (herbal, animal and mineral or obtained by chemical synthesis). According to the Pharmacopoeias used on the current Romanian territory from 1780 to present, there were decreases for herbal (63.96%), animal (7.64%) derived drugs and pharmaceutical forms (33.02%) and a growth for mineral remedies / synthetic drug substances (71.60%).