Romanian Society of Pharmaceutical Sciences
 

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THE RELATIONSHIP BETWEEN BURNING MOUTH SYNDROME AND TREATMENT FOR THYROID DISEASES

ELENA CLAUDIA COCULESCU 1, ECATERINA IONESCU 1, BOGDAN-IOAN COCULESCU 2*,
ANGELICA BENCZE 1, ANCA DRAGOMIRESCU 1, CRISTINA MARIANA STOCHECI 3,
CRISTIAN VLĂDAN 4

1Department of Dental Medicine III, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy,
Bucharest, Romania 2Department of Medical Protection, “Cantacuzino” National Medico-Military Institute for Research and Development,
Bucharest, Romania 3Department of Health Care, Faculty of Sciences, University of Pitești, Pitești, Romania
4 Department of Dental Medicine II, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

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The study aims to evaluate a possible association between the characteristics of pain symptoms and thyroid disorders with specific thyroid replacement medication. Our results indicate a statistically significant association between the presence of thyroid disorders and a change in pain intensity over time. Thus, in 42.86% of all patients with associated thyroid disorders, pain intensity increased over time. We also found a correlation between the increase in the frequency of dysgeusia and the increase in the intensity of the pain symptoms. The administration of drugs for thyroid disorders was significantly associated with the presence of dysgeusia. Also, analysing whether there is a significant correlation between the medication administered for thyroid disorders and the evolution of pain intensity over time, it was observed that in 51.72% of patients with thyroid medication, the pain intensity increased from the onset of the disease versus 20.51% of patients without thyroid medication in whom the intensity of the symptom increased. In conclusion, endocrine disorders and specific medications may be responsible for changes in the taste system. The increase in the frequency of dysgeusia is correlated with the increase in pain intensity in patients with thyroid disorders.