Romanian Society of Pharmaceutical Sciences

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THE ANTIMICROBIAL ACTIVITY OF THYMUS VULGARIS AND ORIGANUM SYRIACUM ESSENTIAL OILS ON STAPHYLOCOCCUS AUREUS, STREPTOCOCCUS PNEUMONIAE AND CANDIDA ALBICANS

ZEINAB LAKIS1, DENISA MIHELE1, ISABELA NICORESCU2, VIRGINIA VULTURESCU3, DENISA IOANA UDEANU1*

1University of Medicine and Pharmacy “Carol Davila”, Faculty of Pharmacy, Clinical Laboratory and Food Safety Department, Bucharest
2Institute for Hygiene and Veterinary Public Health, Bucharest
3National Institute of Chemical- Pharmaceutical Research and Development – ICCF, Bucharest

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The study evaluated the antimicrobial activity of Thymus vulgaris essential oil (29.74% thymol) and Origanum syriacum essential oil (66.64% carvacrol) on standard and human wild type strains of Staphylococcus aureus, Streptococcus pneumoniae and Candida albicans prelevated from the oral cavity. Some possible adverse effects were determined by hematological and blood biochemical routine tests performed on experience animals after the oral treatment with essential oils. The study is part of the preliminary research which aims to obtain new pharmaceutical products with antiseptic activity on oral cavity.