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SYNTHESIS OF NEW THIOUREAS DERIVED FROM 2- (3,4-DIMETHYL-PHENOXYMETHYL)- AND 2-(2,3-DIMETHYL-PHENOXYMETHYL)-BENZOIC ACID WITH POTENTIAL ANTIMICROBIAL ACTIVITY

DRAGOŞ-FLORIAN CIOLAN^1*, DUMITRU LUPULEASA²

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This paper presents the continuation of previous research regarding the synthesis of new thioureas derived from 2-(3,4-dimethyl-phenoxymethyl)-benzoic acid and also the new synthesis of thioureas derived from 2-(2,3-dimethyl-phenoxymethyl)-benzoic acid prepared by adding various primary aromatic amines to 2-(3,4-dimethyl-phenoxymethyl)- benzoyl-isothiocyanate respectively to the 2-(2,3-dimethyl-phenoxymethyl)-benzoylisothiocyanate. We confirmed the chemical structure and the purity of the original compounds by ¹H-NMR, ¹³C- NMR spectral data, IR spectra and using elemental analysis.