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SYNTHESIS OF NEW 2-PHENYLAMINO-5-[(α-ACYLAMINO)-p-X-STIRYL]-1,3,4-THIADIAZOLE COMPOUNDS

TUNDE HORVATH^1*, GEORGETA ŞERBAN¹, STELA CUC²

1.University of Oradea, Faculty of Medicine and Pharmacy, Pharmaceutical Chemistry Department, 29 Nicolae Jiga, 410028 Oradea, România
2.University of Waterloo, Department of Earth Sciences, Environmental Isotope Laboratory, Waterloo, Ontario, Canada

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Cyclization of 4-phenyl-1-[α-acylamino-β-(p-X-phenyl)]acriloyl thiosemicarbazides 2a-h with concentrated sulfuric acid conduCted to 2-phenylamino-5-[(α-acylamino)-p-X-stiryl]-1,3,4-thiadiazole 3a-h. The newly synthesized compounds structures were elucidated by elemental analysis and spectral data.

« Back to Farmacia Journal 2/2014

SYNTHESIS OF NEW 2-PHENYLAMINO-5-[(α-ACYLAMINO)-p-X-STIRYL]-1,3,4-THIADIAZOLE COMPOUNDS

TUNDE HORVATH1*, GEORGETA ŞERBAN1, STELA CUC2

TUNDE HORVATH^1*, GEORGETA ŞERBAN¹, STELA CUC²