Romanian Society of Pharmaceutical Sciences
 

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STUDY REGARDING THE ANTIOXIDANT AND ANTIDIABETIC ACTIVITY OF SYRINGAE VULGARIS FLOS F. VIOLÁCEA TINCTURE IN EXPERIMENTAL DIABETES

ANCA BERBECARU-IOVAN1, ELENA CAMELIA STĂNCIULESCU1*, SORIN BERBECARU-IOVAN2, ANA MARINA ANDREI1, IULIANA CEAUȘU3, CĂTĂLINA GABRIELA PISOSCHI1

1.Faculty of Pharmacy, University of Medicine and Pharmacy, 2 Petru Rareş, 200349, Craiova, Romania
2.Faculty of Medicine, University of Medicine and Pharmacy, 2 Petru Rareş, 200349, Craiova, Romania
3.Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila”, Department of Obstetrics and Gynecology, Dr. I. Cantacuzino Hospital, 5-7 Ion Movila, Bucharest, Romania

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Recently, the interest in possible health benefits of medicinal plants as antioxidant and hypoglycaemic supplements has increased, due to their phytochemical compounds exhibiting potent antioxidant properties. The aim of this study was to assess the in vivo antioxidant activity and antidiabetic potential of a tincture of Syringae vulgaris flos f. violácea (SV), properties less investigated for this plant. We evaluated its influence on glycemia and blood antioxidant enzymes activities in streptozotocin-induced diabetic in rats, compared to an ethanolic extract of Myrtilli folium (MF), already accepted for its antidiabetic and antioxidant properties. Daily administration of ethanolic extracts of SV to diabetic rats reduced blood glucose levels compared to untreated diabetic animals. Blood activity for all antioxidant enzymes was improved in diabetic rats treated with SV extract and we didn’t reported differences between the two tinctures tested. The study provides a scientific validation for the use of Syringae vulgaris flos f. violácea tincture as an adjuvant in the early stages of diabetes in order to prevent its oxidative induced complications.