Romanian Society of Pharmaceutical Sciences

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STATISTICAL STUDY ON THE BACTERIAL SENSIBILITY TESTED IN A SANITARY MICROBIOLOGY LABORATORY

CARMEN ŞERBAN1, NICULINA MITREA1, VIOREL ORDEANU2*

1University of Medicine and Pharmacy “Carol Davila” Bucharest, Romania
2Military Medical Research Center, Bucharest, Romania

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Hospital sanitary microbiology laboratories perform the sanitary inspection, especially in high-risk wards, control hospital flora contamination, which is often multiresistant, perform the periodic monitoring of staff at risk and the examination of persons outside the institution. Data on chemotherapy, germs and tested samples from a sanitary microbiology laboratory revealed specific issues. The database we acquired includes 35 antibiotics, 13 bacterial strains and 13 types of samples, totaling 43,892 bacterial sensibility tests. In statistical terms, only four antibiotics were effective (over 50%), but they are rarely used in therapy. For all the other antibiotics, resistant and intermediate results have prevailed. Pathogenic flora isolated, identified and tested in the hospital is generally multiresistant and creates the risk of nosocomial infections. The result of in vitro testing of bacterial sensibility to antibiotics is not always consistent with the in vivo results of antibiotherapy, the correlation is mainly statistical, but offers one effective indicator for prescribing antibacterial therapy.