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SIMPLE AND EFFICIENT GREEN METHODS INVOLVING MICROWAVES AND MECHANOCHEMISTRY FOR SYNTHESIS OF A SCHIFF LIGAND, 3, 3′-([1,1′-BIPHENYL]-4,4′- DIYLBIS(AZANYLYLIDENE))BIS(INDOLIN-2-ONE) WITH ANTIMICROBIAL ACTIVITY

GEORGE BRĂTULESCU

University of Craiova, Faculty of Sciences, Department of Chemistry, 13 A. I. Cuza Street, 200585, Craiova, Romania

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An azomethine organic ligand was obtained. The synthesis of 3'-([1,1'-biphenyl]-4,4'-diylbis(azanylylidene))bis(indolin-2-one) was accomplished by conventional and green protocols. Three methods have been implemented to obtain the compound. The ligand structure was established by NMR spectra, IR spectrum, UV-vis spectrum and elemental analysis. The comparative study of the experimental protocols was performed. The compound has antibacterial and antifungal activity.