Romanian Society of Pharmaceutical Sciences

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RISK FACTORS FOR POSTOPERATIVE INCISIONAL INFECTION AND ANTI-INFECTIVE EFFECTS OF JEFUYIN DECOCTION IN PATIENTS WITH COLORECTAL CANCER

JINZHI TAN 1, GUIXUE LIU 1, YOU ZHAO 1, ZHI HE 1, WANQING XIAO 1, BENLONG ZHAN 1, YUEYAN ZHOU 2, MINGLIANG ZHOU 3*

1Department of Breast&Anorectal Surgery, Liuyang Traditional Chinese Medicine Hospital, Changsha, 410300, Hunan, China
2Department of Research and Education, Liuyang Traditional Chinese Medicine Hospital, Changsha, 410300, Hunan, China
3Department of General Surgery, The People’s Hospital of Liuyang, Changsha, 410300, Hunan, China

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To investigate the risk factors for postoperative incision infection in colorectal cancer surgery patients, a study was conducted in which 240 patients were included. Study participants were randomly divided into two groups. According to doctor's advice, patients in the control group received routine treatment and care, while patients in the experimental group received traditional Chinese medicine fumigation with Jefuyin decoction. Incision infection rates in patients in the two groups were compared. In addition, enrolled patients were divided into infection group and non-infection group according to the occurrence of postoperative incision infection. Risk factors attributed to infection included diabetes, a history of abdominal surgery, preoperative radiotherapy and chemotherapy, and the presence of a stoma, while subcutaneous drainage was a protective factor. Study results show that patients treated with Jefuyin Decoction had a shorter recovery time, showing that its clinical use is promising for preventing incision infections.