Romanian Society of Pharmaceutical Sciences
 

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RESEARCHES REGARDING OBTAINING SELECTIVE EXTRACTS WITH HYPOGLYCEMIANT PROPERTIES FROM VEGETAL INDIGENOUS PRODUCTS (CICHORII HERBA AND FRAXINI FOLIUM) NOTE III. PHENOLIC COMPOUNDS ANALYSIS FROM FRAXINI FOLIUM

TITINA ALINA IORDACHE1, LAURIAN VLASE2*, VIORICA ISTUDOR1, CERASELA ELENA GÎRD1

1.University of Medicine and Pharmacy ,,Carol Davila“, Faculty of Pharmacy, Department of Pharmacognosy, Phytochemistry, Phytotherapy 6 Traian Vuia, 020956, Bucharest
2.University of Medicine and Pharmacy "Iuliu Hatieganu", Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmaceutics 13, Emil Isac, Cluj-Napoca, Cluj 400023

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The aim of this study was to establish the polyphenolic derivatives content (phenolcarboxylic acids, flavones and tannin) from Fraxini folium (Ash leaves) harvested at different stages of development compared to those from S.C. Phytotherapy Bucharest S.A, Romania, and to verify their presence by high performance liquid chromatography coupled with mass spectrometry and UV (HPLC/MS/UV). Leaves harvested in June had the highest content in polyphenolic derivatives. By HPLC/MS and HPLC/UV were identified luteolin, caftaric and gentisic acids not mentioned in the consulted literature.