Romanian Society of Pharmaceutical Sciences

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QUANTITATIVE ANALYSIS OF PHENOLIC COMPOUNDS FROM SALVIA OFFICINALIS L. LEAVES

CERASELA ELENA GÎRD, IOANA NENCU, TEODORA COSTEA, LIGIA ELENA DUŢU*, MARIA LIDIA POPESCU, NICOLETA CIUPITU

University of Medicine and Pharmacy ”Carol Davila”, Faculty of Pharmacy, Pharmacognosy, Phytochemistry, Phytotherapy Department, 6 Traian Vuia Street, 020956, Bucharest, Romania

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The aim of this work was to investigate changes in total phenolic, flavonoids and phenolcarboxylic acids (chlorogenic, caffeic, rosmarinic) contents of indigenous sage (Salvia officinalis L.) leaves collected monthly (from May to September) and their correlation with climate conditions. Our results showed that variation in total phenolics amount can be explained by changes in environmental factors (such as temperature and humidity). The highest content of rosmarinic acid was detected in May (1.0560 g%), July (1.4270 g%) and September (1.3325 g%). Total polyphenols, phenolcarboxylic acids and flavonoids contents showed the same trend, a constant increase being recorded from May to July (3.2698±0.964 g%, 2.4041±0.0964 g%, 1.4415±0.040 g% for May and 6.3297±0.2042 g%, 5.4916±0.2273 g%, 2.0994±0.0944 g% respectively).