Romanian Society of Pharmaceutical Sciences

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PHYTOCHEMICAL INVESTIGATION AND ANTIOXIDANT POTENTIAL OF ONONIS ARVENSIS L

TÜNDE DÉNES 1, NÓRA PAPP 1*, ERZSÉBET FOGARASI 2, SAROLTA-EDINA MARTON 3, ERZSÉBET VARGA 3

1Department of Pharmacognosy, University of Pécs, Pécs, Hungary
2Department of Toxicology and Biopharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology from Târgu Mureș, Târgu Mureş, Romania
3Department of Pharmacognosy and Phytotherapy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology from Târgu Mureș, Târgu Mureş, Romania

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Phytochemicals, such as polyphenols, are strong antioxidants and have an important role in the human health system. The present study investigates the content of total phenolics, flavonoids, tannins and the antioxidant activity of Ononis arvensis using the in vitro ABTS•+ antioxidant assay for the first time. Extracts were prepared with three different types of solvents: water, 50% ethanol, methanol. Among the studied parts, the 50% ethanol extract of the flower showed the highest polyphenolic content (96.33 ± 7.7 mg GAE/100 g dw), while the 50% ethanol extract of the flower (81.58 ± 3.1 mg QE/100 g dw) and the aerial part (21.15 ± 1.3 mg QE/100 g dw) showed the highest total flavonoid content. The total tannin concentration of the aerial part had a low value (0.15 ± 0.04%). The antioxidant effect was detected in all extracts obtained from flowers; however, ethanol and methanol were more effective.