Romanian Society of Pharmaceutical Sciences

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PHARMACEUTICAL ASSESMENT OF ROMANIAN CROPS OF ANTHRISCUS SYLVESTRIS (APIACEAE)

BRUNO ŞTEFAN VELESCU 1#, VALENTINA ANUŢA 2#*, GEORGE MIHAI NIȚULESCU 3#, OCTAVIAN TUDOREL OLARU 4#, ALINA ORȚAN 5#, DANIELA IONESCU 6#, MIHAELA VIOLETA GHICA 2#, CRISTINA MANUELA DRĂGOI 7#, CRISTINA ELENA DINU PÎRVU 2#

1.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmacology and Clinical Pharmacy, 6 Traian Vuia Str., 020956, Bucharest, Romania
2.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Physical and Colloidal Chemistry, 6 Traian Vuia Str., 020956, Bucharest, Romania
3.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 6 Traian Vuia Str., 020956, Bucharest, Romania
4.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Botany, 6 Traian Vuia Str., 020956, Bucharest, Romania
5.University of Agronomic Sciences and Veterinary Medicine, Faculty of Land Reclamation and Environmental Engineering, Bucharest, Romania
6.S.C. Hofigal Export-Import S.A., Bucharest, Romania Intr. Serelor Street no.2, district 4, 042124
7.“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Biochemistry, 6 Traian Vuia Str., 020956, Bucharest, Romania
*corresponding author: vali_anuta@yahoo.com
# All authors have equal contribution.

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Anthriscus sylvestris is a traditional remedy for various diseases due to the lignans contained by the root. The aerial parts of the plant are also used in the traditional medicine, but the pharmacological studies are limited. The objective of the study was to evaluate the anti-inflammatory activity of A. sylvestris aerial parts in order to capitalize the plants highly adaptability and ability to grow rapidly in almost any type of soil. The obtained results proved that the obtained and characterized A. sylvestris aerial parts extract exerted anti-inflammatory effects in rat induced inflammation models.