Romanian Society of Pharmaceutical Sciences
 

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PAIN THERAPY ASSOCIATED WITH ORTHODONTIC TREATMENT

RALUCA ALEXANDRA GRIGORE1, ANA-MARIA MIHAI1, DRAGOȘ FLORIAN CIOLAN2*, VIORICA ȚĂRMURE3, ECATERINA IONESCU1

1.University of Medicine and Pharmacy „Carol Davila” Bucharest, Faculty of Dentistry, Department of Orthodontics and Dento-facial Orthopedics 4-6, Eforie street, 50037, Bucharest, Romania.
2 .University of Medicine and Pharmacy „Carol Davila” Bucharest, Faculty of Pharmacy, Department of Pharmaceutical Chemistry 6, Traian Vuia street, 020956, Bucharest, Romania.
3 .University of Medicine and Pharmacy Cluj, “Iuliu Hatieganu”, Faculty of Dentistry, Department of Orthodontics 33, Moţilor street, Cluj Romania

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Orthodontics is based on tooth movement through bone resulting from the application of mechanical forces. The bone remodeling takes place through an inflammatory process associated with pain or discomfort. Many practitioners recommend to their patients to use analgesics such as non-steroidal antiinflammatory drugs (NSAIDs) to control the discomfort associated with the inflammatory process, unaware that studies have shown that most of NSAIDs inhibit orthodontic tooth movement. This review tries to find the best therapeutically approach in terms of pain relief and rate of orthodontic movement based on today knowledge.