Romanian Society of Pharmaceutical Sciences

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NEW SYNTHESIS IN THE ACYL-OXIMINE DERIVATIVES SERIA

DANA MIHAELA CIOROIANU1, DIANA CAMELIA NUȚĂ1*, MIRON TEODOR CĂPROIU2, ALEXANDRU VASILE MISSIR1, CARMEN LIMBAN1, ILEANA CORNELIA CHIRIȚĂ1, LAURENȚIU MORUȘCIAG1

1.University of Medicine and Pharmacy „Carol Davila” Bucharest, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Bucharest, Romania, 6 Traian Vuia St., Bucharest, 020956, Romania
2.The Organic Chemistry Center of Romanian Academy “C. D. Neniţescu”, Splaiul Independenţei 202B, Bucharest, Romania

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This paper is a continuation of our research concerning the obtaining and characterization of other new acyl-oximine derivatives with tricyclic structure, which may become new compounds with pharmacological properties like tricyclic antidepressants. These substances are O-acyl-oximine derivatives with 5H-dibenzo[a,d]cyclo-heptatriene structure, whose structures were confirmed by elemental analysis, IR and NMR- spectrometry.