Romanian Society of Pharmaceutical Sciences

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NEW APPROACHES REGARDING THE DYNAMICS OF THE DOPING PHARMACOLOGIC AGENTS IN SPORTS

GABRIEL PIŢIGOI1, CĂTĂLIN PĂUNESCU1*, NICULINA MITREA2, DANIELA BACONI3, MIHAELA PĂUNESCU4, CLAUDIA BURCEA1, ANDREEA LETIŢIA ARSENE2

1Department of Physical Education and Sport, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, Medical Heroes Avenue, No 8, Bucharest, 050474, Romania
2Department of Biochemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Traian Vuia street, no.6, Bucharest, Romania
3Department of Toxicology, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Traian Vuia street, no.6, Bucharest, Romania
4National University of Physical Education and Sports (NUPES), Constantin Noica street, no.140, 060057, Bucharest, Romania

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The use of doping pharmacological agents is one of the major negative aspects in sports, that has to be carefully monitored. The present study reveals several important aspects regarding drug abuse among the sportsmen. The study included 75 subjects that volunteered for this research. They were both male and female (63% males and 37% females) and associated with 12 different sports. The participants were included in the study based on their signed informed consent and their agreement to participate in the study anonymously. All participants were subjected to a survey, where they could fill personal (but anonymous) information regarding the potential use of doping substances. Since more than 60% of the athletes accepted that they used doping drugs, and a great number of them admitted they did not know or were not sure of the biological effects of these substances, sports officials are required to offer information to every player informing them about these substances, because adequate knowledge about these drugs and their adverse effects might help them to avoid using these substances. The major route of doping substances administration was the oral one, followed by dermic and intramuscular ones. Consequent to their administration, athletes noticed different modifications due to the side effects of abuse substances: psychological, androgenic, cardiovascular, dermatologic and muscular effects.